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Combined siRNA and Small-Molecule Phenotypic Screening Identifies Targets Regulating Rhinovirus Replication in Primary Human Bronchial Epithelial Cells. |
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Antiviral Effects of Menthol on Coxsackievirus B. |
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Novel Ionophores Active against La Crosse Virus Identified through Rapid Antiviral Screening. |
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Temperature controlled high-throughput magnetic tweezers show striking difference in activation energies of replicating viral RNA-dependent RNA polymerases. |
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Protease Inhibitors: Candidate Drugs to Inhibit Severe Acute Respiratory Syndrome Coronavirus 2 Replication. |
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2020 |
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2020 |
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Potential role of zinc supplementation in prophylaxis and treatment of COVID-19. |
Med Hypotheses |
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Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review. |
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Emerging Human Coronavirus Infections (SARS, MERS, and COVID-19): Where They Are Leading Us. |
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Microglia HMC3 cells are highly susceptible to Rhinovirus infection. |
Virus Res |
2020 |
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Viral structural proteins as targets for antivirals. |
Curr Opin Virol |
2020 |
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A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2. |
Nat Commun |
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A synthetic STING agonist inhibits the replication of human parainfluenza virus 3 and rhinovirus 16 through distinct mechanisms. |
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2020 |
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2020 |
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SARS-CoV-2 infection, COVID-19 pathogenesis, and exposure to air pollution: What is the connection? |
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2021 |
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Stimulator of interferon genes (STING) is an essential proviral host factor for human rhinovirus species A and C. |
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Intercellular movement of plant RNA viruses: Targeting replication complexes to the plasmodesma for both accuracy and efficiency. |
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Wu X;Cheng X |
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Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C. |
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2020 |
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Convalescent Memory T Cell Immunity in Individuals with Mild or Asymptomatic SARS-CoV-2 Infection May Result from an Evolutionarily Adapted Immune Response to Coronavirus and the \'Common Cold\'. |
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2020 |
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Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies. |
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Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses. |
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Comparative in vitro analysis of inhibition of rhinovirus and influenza virus replication by mucoactive secretolytic agents and plant extracts. |
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2020 |
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Glucocorticoids impair type I IFN signalling and enhance rhinovirus replication. |
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2021 |
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Inhibition of coronavirus infection by a synthetic STING agonist in primary human airway system. |
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2021 |
Zhu Q;Zhang Y;Wang L;Yao X;Wu D;Cheng J;Pan X;Liu H;Yan Z;Gao L |
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Infection of porcine small intestinal enteroids with human and pig rotavirus A strains reveals contrasting roles for histo-blood group antigens and terminal sialic acids. |
PLoS Pathog |
2021 |
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Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus. |
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2021 |
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Iota-carrageenan neutralizes SARS-CoV-2 and inhibits viral replication in vitro. |
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2021 |
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Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic. |
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2021 |
To KK;Sridhar S;Chiu KH;Hung DL;Li X;Hung IF;Tam AR;Chung TW;Chan JF;Zhang AJ;Cheng VC;Yuen KY |
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Combined in silico and in vitro approaches identified the antipsychotic drug lurasidone and the antiviral drug elbasvir as SARS-CoV2 and HCoV-OC43 inhibitors. |
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2021 |
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Human Rhinovirus Infection Blocks Severe Acute Respiratory Syndrome Coronavirus 2 Replication Within the Respiratory Epithelium: Implications for COVID-19 Epidemiology. |
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2021 |
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The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways. |
PLoS Pathog |
2021 |
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Rhinovirus and Cell Death. |
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2021 |
Kerr SL;Mathew C;Ghildyal R |
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Reactive oxygen species as potential antiviral targets. |
Rev Med Virol |
2022 |
Sander WJ;Fourie C;Sabiu S;O'Neill FH;Pohl CH;O'Neill HG |
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Differential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells. |
J Gen Virol |
2021 |
Dissanayake TK;Yan B;Ng AC;Zhao H;Chan G;Yip CC;Sze KH;To KK |
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Naunyn Schmiedebergs Arch Pharmacol |
2021 |
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Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers. |
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2021 |
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Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics. |
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2021 |
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PGC-1alpha mediates a metabolic host defense response in human airway epithelium during rhinovirus infections. |
Nat Commun |
2021 |
Michi AN;Yipp BG;Dufour A;Lopes F;Proud D |
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Rhinovirus Reduces the Severity of Subsequent Respiratory Viral Infections by Interferon-Dependent and -Independent Mechanisms. |
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2021 |
Van Leuven JT;Gonzalez AJ;Ijezie EC;Wixom AQ;Clary JL;Naranjo MN;Ridenhour BJ;Miller CR;Miura TA |
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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2. |
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2021 |
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Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIbeta) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses. |
ChemMedChem |
2021 |
Grazia Martina M;Vicenti I;Bauer L;Crespan E;Rango E;Boccuto A;Olivieri N;Incerti M;Zwaagstra M;Allodi M;Bertoni S;Dreassi E;Zazzi M;van Kuppeveld FJM;Maga G;Radi M |
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The proton ATPase inhibitor bafilomycin A1 reduces the release of rhinovirus C and cytokines from primary cultures of human nasal epithelial cells. |
Virus Res |
2021 |
Yamaya M;Deng X;Kikuchi A;Sugawara M;Saito N;Kubo T;Momma H;Kawase T;Nakagome K;Shimotai Y;Nishimura H |
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Endemic and Indigenous Plants from Mascarene Islands with Antiviral Propensities. |
Curr Drug Targets |
2022 |
Fawzi MM;Sharmeen JB;Juliano H;Chaker EK |
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Inhibitory effect of traditional herbal (kampo) medicines on the replication of human parainfluenza virus type 2 in vitro. |
Drug Discov Ther |
2021 |
Uematsu J;Yamamoto H;Kihira S;Sakai-Sugino K;Ishiyama Y;Chindoh M;Baba A;Kazuta R;Hasegawa T;Fujimoto K;Funauchi A;Itoh A;Ookohchi A;Satoh S;Maeda Y;Kawano M;Tsurudome M;Nishio M;Hirai K;O'Brien M;Komada H |
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Comparative analysis of the molecular mechanism of resistance to vapendavir across a panel of picornavirus species. |
Antiviral Res |
2021 |
Lanko K;Sun L;Froeyen M;Leyssen P;Delang L;Mirabelli C;Neyts J |
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Viral polymerase binding and broad-spectrum antiviral activity of molnupiravir against human seasonal coronaviruses. |
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2021 |
Wang Y;Li P;Solanki K;Li Y;Ma Z;Peppelenbosch MP;Baig MS;Pan Q |
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Air Pollution Exposure Impairs Airway Epithelium IFN-beta Expression in Pre-School Children. |
Front Immunol |
2021 |
Bonato M;Gallo E;Turrin M;Bazzan E;Baraldi F;Saetta M;Gregori D;Papi A;Contoli M;Baraldo S |
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Apoptosis Enhances the Replication of Human Coronavirus OC43. |
Viruses |
2021 |
Maharjan S;Kang M;Kim J;Kim D;Park S;Kim M;Baek K;Lee Y;Kwon HJ |
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RNA helicases required for viral propagation in humans. |
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2021 |
Marecki JC;Belachew B;Gao J;Raney KD |
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Sequential infections with rhinovirus and influenza modulate the replicative capacity of SARS-CoV-2 in the upper respiratory tract. |
Emerg Microbes Infect |
2022 |
Essaidi-Laziosi M;Alvarez C;Puhach O;Sattonnet-Roche P;Torriani G;Tapparel C;Kaiser L;Eckerle I |
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The Expression of ephrinA1/ephA2 Receptor Increases in Chronic Rhinosinusitis and ephrinA1/ephA2 Signaling Affects Rhinovirus-Induced Innate Immunity in Human Sinonasal Epithelial Cells. |
Front Immunol |
2021 |
Lee SH;Kang SH;Han MS;Kwak JW;Kim HG;Lee TH;Lee DB;Kim TH |
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Rhinovirus C replication is associated with the endoplasmic reticulum and triggers cytopathic effects in an in vitro model of human airway epithelium. |
PLoS Pathog |
2022 |
Gagliardi TB;Goldstein ME;Song D;Gray KM;Jung JW;Ignacio MA;Stroka KM;Duncan GA;Scull MA |
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Genome-scale CRISPR screens identify host factors that promote human coronavirus infection. |
Genome Med |
2022 |
Grodzki M;Bluhm AP;Schaefer M;Tagmount A;Russo M;Sobh A;Rafiee R;Vulpe CD;Karst SM;Norris MH |
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TLR7 agonist loaded airway epithelial targeting nanoparticles stimulate innate immunity and suppress viral replication in human bronchial epithelial cells. |
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2022 |
Kan S;Grainge C;Nichol K;Reid A;Knight D;Sun Y;Bartlett N;Liang M |
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Viral illnesses and sports performance. |
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Enteroviral replication inhibition by N-Alkyl triazolopyrimidinone derivatives through a non-capsid binding mode. |
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2022 |
Kumar Biswas B;Soo Shin J;Malpani YR;Hwang D;Jung E;Bong Han S;Vishakantegowda AG;Jung YS |
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Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication. |
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Flavonols and dihydroflavonols inhibit the main protease activity of SARS-CoV-2 and the replication of human coronavirus 229E. |
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2022 |
Zhu Y;Scholle F;Kisthardt SC;Xie DY |
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Cell pyroptosis in picornavirus and its potential for treating viral infection. |
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2022 |
Wang Z;Yu H;Zhuang W;Chen J;Jiang Y;Guo Z;Huang X;Liu Q |
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Rhinoviruses usurp STING for replication. |
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Positive strand RNA viruses differ in the constraints they place on the folding of their negative strand. |
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2022 |
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Human lung vascular endothelium may limit viral replication and recover in time upon the infection with rhinovirus HRV16. |
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2022 |
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pUL36 Deubiquitinase Activity Augments Both the Initiation and the Progression of Lytic Herpes Simplex Virus Infection in IFN-Primed Cells. |
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2022 |
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RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5\'-untranslated region. |
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2023 |
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Fragile X-Related Protein FXR1 Controls Human Adenovirus Capsid mRNA Metabolism. |
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2023 |
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Anisomycin inhibits Coxsackievirus B replication by promoting the lysosomal degradation of eEF1A1. |
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37265497
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HBoV-1: virus structure, genomic features, life cycle, pathogenesis, epidemiology, diagnosis and clinical manifestations. |
Front Cell Infect Microbiol |
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37749807
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Human bocavirus respiratory infection: Tracing the path from viral replication and virus-cell interactions to diagnostic methods. |
Rev Med Virol |
2023 |
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Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions. |
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Early interaction between animal viruses and cells. |
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Use of zonal ultracentrifuge systems for biophysical studies of rhinoviruses. |
J Virol |
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4306834
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Growth characteristics of rhinoviruses in human gingival cells. |
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Rhinovirus replication in suspension cultures of HeLa cells. |
Proc Soc Exp Biol Med |
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Organ cultures in virology. |
Prog Med Virol |
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Effect of magnesium on replication of rhinovirus HGP. |
J Virol |
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Effect of Mycoplasma pneumoniae on rhinovirus ribonucleic acid synthesis in KB cells. |
Antimicrob Agents Chemother (Bethesda) |
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4321445
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Organ cultures of human fallopian tubes for the propagation of viruses. |
Arch Gesamte Virusforsch |
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The formation of interferon during acute respiratory virus infection of volunteers. |
Arch Gesamte Virusforsch |
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Nucleoside peptides. 2. Synthesis of certain 5-N-aminoacyl and 5-N-peptidyl derivatives of 5-aminouridine. |
J Med Chem |
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Electron microscopic study of rhinovirus replication in human fetal lung cells. |
Jpn J Microbiol |
1971 |
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The antiviral activity of a triazinoindole (SK&F 30097). |
Proc Soc Exp Biol Med |
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Antiviral agents. 5H-as-Triazino(5,6-b) indoles. |
J Med Chem |
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[The effect of pancreatin on rhinovirus multiplication and plaque formation]. |
Vopr Virusol |
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Studies with a rhinovirus of bovine origin. I. Growth in vitro of strain RS 3x. |
Arch Gesamte Virusforsch |
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Relation between naturally acquired immunity and infectivity of two rhinoviruses in volunteers. |
J Infect Dis |
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4335940
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Naturally occurring and artificially produced components of three rhinoviruses. |
Virology |
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Evaluation of gentamicin for use in virology and tissue culture. |
Appl Microbiol |
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RNA and protein synthesis in rhinovirus infected HeLa cells. |
Proc Soc Exp Biol Med |
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Inhibition of RNA virus replication in vitro by 3-deazacytidine and 3-deazauridine. |
Proc Soc Exp Biol Med |
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Azapurine nucleosides. 3. Synthesis of 7-( -D-ribofuranosyl)imidazo(4,5-d)-v-triazin-4-one(2-azainosine) and related derivatives. |
J Med Chem |
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Interaction of herpes simplex virus and rhinovirus in cell culture. Brief report. |
Arch Gesamte Virusforsch |
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Rhinoviruses. |
Annu Rev Microbiol |
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The antiviral effect of a triazinoindole (SK&F 40491) in rhinovirus infected gibbons. |
Proc Soc Exp Biol Med |
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The in vitro antiviral activity of a triazinoindole (SK&F 40491). |
Proc Soc Exp Biol Med |
1972 |
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Fish viruses: buffers and methods for plaquing eight agents under normal atmosphere. |
Appl Microbiol |
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Interferon induction by rhinoviruses and effect of interferon on rhinovirus yields in human cell lines. |
Proc Soc Exp Biol Med |
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Picornavirus receptors and picornavirus multiplication in human-mouse hybrid cell lines. |
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Growth of rhinovirus type 14. Brief report. |
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The influence of mycoplasmas on the cytopathic effect of varicella virus. |
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Replication of rhinovirus RNA. |
J Gen Virol |
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Preliminary observations pertaining to polyadenylation of rhinovirus RNA. |
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Studies on the lysosomes of L132 cells infected with either rhinovirus type 2 or poliovirus type 1. |
J Gen Virol |
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Zinc ions inhibit replication of rhinoviruses. |
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Inhibition of rhinovirus RNA synthesis in diploid cells by a substituted guanidine compound having a different mode of action from guanidine. |
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Sequential steps in attachment of human rhinovirus type 2 to HeLa cells. |
J Gen Virol |
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[Characteristics of the mechanism of transmission of the pathogen in respiratory infections (review of the literature)]. |
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[Stabilization of the infectious activity of rhinovirus in prolonged storage]. |
Vopr Virusol |
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[Ambulatory treatment of virus-related respiratory tract diseases. 2. Biology and diagnosis of viruses of the respiratory tract]. |
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[Proteolytic enzymes in virological studies]. |
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Antiviral activity of scillarenin, a plant bufadienolide. |
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The use of indirect fluorescent antibody technique in studies on the reproduction of rhinoviruses and for the detection of rhinoviral antigen in materials from patients with acute respiratory diseases and conjunctivitides. |
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The role of interferon in the response to infection. |
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Electron microscopy of equine respiratory viruses in organ cultures of equine fetal respiratory tract epithelium. |
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Synthesis of syn and anti isomers of 6-[[(hydroxyimino)phenyl]methyl]-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-2-am ine. Inhibitors of rhinovirus multiplication. |
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Identification and characterization of a bovine rhinovirus isolated from Iowa cattle with acute respiratory tract disease. |
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The structure and replication of rhinoviruses. |
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Antipicornavirus flavone Ro 09-0179. |
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Direct and specific inactivation of rhinovirus by chalcone Ro 09-0410. |
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Inhibition of an early stage of rhinovirus replication by dichloroflavan (BW683C). |
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Picornaviral structure and protein synthesis. |
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Activity of 2-(3,4-dichlorophenoxy)-5-nitrobenzonitrile (MDL-860) against picornaviruses in vitro. |
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J Virol |
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The 3\' untranslated region of picornavirus RNA: features required for efficient genome replication. |
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Rhinoviruses and cells: molecular aspects. |
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Rhinovirus infection of the normal human airway. |
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The foot-and-mouth disease virus leader proteinase gene is not required for viral replication. |
J Virol |
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SDZ 35-682, a new picornavirus capsid-binding agent with potent antiviral activity. |
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Localization of human rhinovirus replication in the upper respiratory tract by in situ hybridization. |
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Use of drug-resistance mutants to identify functional regions in picornavirus capsid proteins. |
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Efficient neutralization and disruption of rhinovirus by chimeric ICAM-1/immunoglobulin molecules. |
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The 5\'-untranslated regions of picornavirus RNAs contain independent functional domains essential for RNA replication and translation. |
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[Screening test of crude drug extract on anti-HIV activity]. |
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Sensitivity of NCI-H292 human lung mucoepidermoid cells for respiratory and other human viruses. |
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8383239
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WIN 52035-2 inhibits both attachment and eclipse of human rhinovirus 14. |
J Virol |
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Entry of poliovirus into cells does not require a low-pH step. |
J Virol |
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Chiral discrimination and antipicornavirus activity of 6-oxazolinylisoflavan. |
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Physical and chemical methods for enhancing rapid detection of viruses and other agents. |
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Rhinovirus enters but does not replicate inside monocytes and airway macrophages. |
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Co-operative interaction between the initiator E1 and the transcriptional activator E2 is required for replicator specific DNA replication of bovine papillomavirus in vivo and in vitro. |
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Studies on photoinactivation by various phthalocyanines of a free or replicating non-enveloped virus. |
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Synthesis and activity of piperazine-containing antirhinoviral agents and crystal structure of SDZ 880-061 bound to human rhinovirus 14. |
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[Effects of qiwei baizhu san in inhibiting replication of human rotavirus in vitro]. |
Zhongguo Zhong Xi Yi Jie He Za Zhi |
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Synthesis and antirhinovirus activity of 3-(diethylamino)-5-phenylisoxazole derivatives. |
Farmaco |
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Mouse cells expressing human intercellular adhesion molecule-1 are susceptible to infection by coxsackievirus A21. |
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The refined structure of human rhinovirus 16 at 2.15 A resolution: implications for the viral life cycle. |
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Protective responses in mice to vaccination with multiply administered cold-adapted influenza vaccine reassortants and wild-type viruses. |
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[Rhinovirus infection and expression of adhesion molecules in human tracheal epithelium]. |
Nihon Kyobu Shikkan Gakkai Zasshi |
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Replication-competent picornaviruses with complete genomic RNA 3\' noncoding region deletions. |
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Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1beta. |
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Nitric oxide inhibits rhinovirus-induced cytokine production and viral replication in a human respiratory epithelial cell line. |
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Major and minor receptor group human rhinoviruses penetrate from endosomes by different mechanisms. |
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Analysis of host range restriction determinants in the rabbit model: comparison of homologous and heterologous rotavirus infections. |
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The predominant elF4G-specific cleavage activity in poliovirus-infected HeLa cells is distinct from 2A protease. |
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Direct cleavage of elF4G by poliovirus 2A protease is inefficient in vitro. |
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Bovee ML;Lamphear BJ;Rhoads RE;Lloyd RE |
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Synthesis and evaluation of peptidyl Michael acceptors that inactivate human rhinovirus 3C protease and inhibit virus replication. |
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Binding of a cellular factor to the 3\' untranslated region of the RNA genomes of entero- and rhinoviruses plays a role in virus replication. |
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Rhinovirus replication in HeLa cells cultured under conditions of simulated microgravity. |
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Polymerase chain reaction-based detection of rhinovirus, respiratory syncytial virus, and coronavirus in otitis media with effusion. |
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The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication. |
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Anti-picornavirus activity of synthetic flavon-3-yl esters. |
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Approaches to antiviral chemotherapy for acute respiratory infections. |
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2-Amino-3-substituted-6-[(E)-1-phenyl-2-(N-methylcarbamoyl)vinyl]imid azo[1,2-a]pyridines as a novel class of inhibitors of human rhinovirus: stereospecific synthesis and antiviral activity. |
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Inhibition of 3C protease from human rhinovirus strain 1B by peptidyl bromomethylketonehydrazides. |
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