| Title | Different patterns of polyadenylation of rhinovirus: specified RNA during multiplication in human aneuploid and diploid cells. | ||
| Author | Macnaughton, M R; Dimmock, N J | ||
| Journal | J Gen Virol | Publication Year/Month | 1976-Feb |
| PMID | 181536 | PMCID | -N/A- |
The polyadenylation of rhinovirus-specified RNA in aneuploid HeLa cells and diploid human embryo lung (HEL) cells has been investigated. Polyadenylation occurs at a faster rate and more extensively to virus-specified RNA in infected HEL cells compared with HeLa cells. Poly(A) is added post-transcriptively in both cell types. Furthermore the addition of adenosine or poly(A) during virus multiplication increases the polyadenylation of virus single-stranded RNAs in both cell types, but to a greater extent in HeLa cells.