| Title | [Effects of qiwei baizhu san in inhibiting replication of human rotavirus in vitro]. | ||
| Author | He, S T; He, F Z; Wu, C R | ||
| Journal | Zhongguo Zhong Xi Yi Jie He Za Zhi | Publication Year/Month | 1995-Nov |
| PMID | 8732153 | PMCID | -N/A- |
| Affiliation | 1.Hunan Academy of TCM, Changsha. | ||
Qiwei Baizhu San was found to have an inhibitory effect on human rotavirus (HRV)at monolayer of MA104 Cells. A 50% reduction in plaque number, a 10(1.86)TCID50 decrease in viral replication index and around 60% inhibition in viral RNA synthesis were observed at concentration of 100 mg/ml. Furthermore, the cytotoxicity of the decoction was low, while its promoting effect on growth and proliferation of the culture cells was observed at the concentrations of 12.5-50 mg/ml. The decoction was also found to have effects in prolonging the survival time of HRV infected cells and promoting the regeneration of the infected cells.