PMID Title Journal Publication Year Author View in RVdb
10098667 Design, synthesis, and evaluation of azapeptides as substrates and inhibitors for human rhinovirus 3C protease. Bioorg Med Chem Lett 1999 Venkatraman S;Kong J;Nimkar S;Wang QM;Aube J;Hanzlik RP View More
10197964 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. J Med Chem 1999 Dragovich PS;Prins TJ;Zhou R;Fuhrman SA;Patick AK;Matthews DA;Ford CE;Meador JW 3rd;Ferre RA;Worland ST View More
10197965 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements. J Med Chem 1999 Dragovich PS;Prins TJ;Zhou R;Webber SE;Marakovits JT;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Ford CE;Burke BJ;Rejto PA;Hendrickson TF;Tuntland T;Brown EL;Meador JW 3rd;Ferre RA;Harr JE;Kosa MB;Worland ST View More
10224078 Identification and characterization of human rhinovirus-14 3C protease deamidation isoform. J Biol Chem 1999 Cox GA;Johnson RB;Cook JA;Wakulchik M;Johnson MG;Villarreal EC;Wang QM View More
10353638 Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides. Bioorg Med Chem 1999 Dragovich PS;Zhou R;Skalitzky DJ;Fuhrman SA;Patick AK;Ford CE;Meador JW 3rd;Worland ST View More
10396129 Protease inhibitors as potential antiviral agents for the treatment of picornaviral infections. Prog Drug Res 1999 Wang QM View More
10465543 Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids. Bioorg Med Chem Lett 1999 Dragovich PS;Webber SE;Prins TJ;Zhou R;Marakovits JT;Tikhe JG;Fuhrman SA;Patick AK;Matthews DA;Ford CE;Brown EL;Binford SL;Meador JW 3rd;Ferre RA;Worland ST View More
10500114 Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes. Proc Natl Acad Sci U S A 1999 Matthews DA;Dragovich PS;Webber SE;Fuhrman SA;Patick AK;Zalman LS;Hendrickson TF;Love RA;Prins TJ;Marakovits JT;Zhou R;Tikhe J;Ford CE;Meador JW;Ferre RA;Brown EL;Binford SL;Brothers MA;DeLisle DM;Worland ST View More
10507322 Rhinovirus 2A proteinase mediated stimulation of rhinovirus RNA translation is additive to the stimulation effected by cellular RNA binding proteins. Virus Res 1999 Hunt SL;Skern T;Liebig HD;Kuechler E;Jackson RJ View More
10507325 The structures of picornaviral proteinases. Virus Res 1999 Seipelt J;Guarne A;Bergmann E;James M;Sommergruber W;Fita I;Skern T View More
10508022 In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease. Antimicrob Agents Chemother 1999 Patick AK;Binford SL;Brothers MA;Jackson RL;Ford CE;Diem MD;Maldonado F;Dragovich PS;Zhou R;Prins TJ;Fuhrman SA;Meador JW;Zalman LS;Matthews DA;Worland ST View More
10523291 The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis. EMBO J 1999 Petersen JF;Cherney MM;Liebig HD;Skern T;Kuechler E;James MN View More
10590122 A cysteine-rich motif in poliovirus protein 2C(ATPase) is involved in RNA replication and binds zinc in vitro. J Virol 2000 Pfister T;Jones KW;Wimmer E View More
10636240 Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2000 Dragovich PS;Zhou R;Webber SE;Prins TJ;Kwok AK;Okano K;Fuhrman SA;Zalman LS;Maldonado FC;Brown EL;Meador JW 3rd;Patick AK;Ford CE;Brothers MA;Binford SL;Matthews DA;Ferre RA;Worland ST View More
10640559 The 2A proteins of three diverse picornaviruses are related to each other and to the H-rev107 family of proteins involved in the control of cell proliferation. J Gen Virol 2000 Hughes PJ;Stanway G View More
10770757 Inhibition of human rhinovirus-induced cytokine production by AG7088, a human rhinovirus 3C protease inhibitor. Antimicrob Agents Chemother 2000 Zalman LS;Brothers MA;Dragovich PS;Zhou R;Prins TJ;Worland ST;Patick AK View More
10794684 Substituted benzamide inhibitors of human rhinovirus 3C protease: structure-based design, synthesis, and biological evaluation. J Med Chem 2000 Reich SH;Johnson T;Wallace MB;Kephart SE;Fuhrman SA;Worland ST;Matthews DA;Hendrickson TF;Chan F;Meador J 3rd;Ferre RA;Brown EL;DeLisle DM;Patick AK;Binford SL;Ford CE View More
10867028 2A proteinase of human rhinovirus cleaves cytokeratin 8 in infected HeLa cells. J Biol Chem 2000 Seipelt J;Liebig HD;Sommergruber W;Gerner C;Kuechler E View More
10950388 Antiviral therapy for enteroviruses and rhinoviruses. Antivir Chem Chemother 2000 Rotbart HA View More
10999479 S-nitrosothiols as novel, reversible inhibitors of human rhinovirus 3C protease. Bioorg Med Chem Lett 2000 Xian M;Wang QM;Chen X;Wang K;Wang PG View More
11007981 Characterization of the active site thiol group of rhinovirus 2A proteinase. FEBS Lett 2000 Sarkany Z;Skern T;Polgar L View More
11034318 Extremely efficient cleavage of eIF4G by picornaviral proteinases L and 2A in vitro. FEBS Lett 2000 Glaser W;Skern T View More
11118371 Complete nucleotide sequence of the chiba virus genome and functional expression of the 3C-like protease in Escherichia coli. Virology 2000 Someya Y;Takeda N;Miyamura T View More
11161279 The C-terminal residues of poliovirus proteinase 2A(pro) are critical for viral RNA replication but not for cis- or trans-proteolytic cleavage. J Gen Virol 2001 Li X;Lu HH;Mueller S;Wimmer E View More
11162821 Activation of human rhinovirus-14 3C protease. Virology 2001 Wang QM;Johnson RB View More
11166856 The treatment of rhinovirus infections: progress and potential. Antiviral Res 2001 Turner RB View More
11274152 Disruption of the interaction of mammalian protein synthesis eukaryotic initiation factor 4B with the poly(A)-binding protein by caspase- and viral protease-mediated cleavages. J Biol Chem 2001 Bushell M;Wood W;Carpenter G;Pain VM;Morley SJ;Clemens MJ View More
11302940 Liquid chromatography-mass spectrometry and liquid chromatography-NMR characterization of in vitro metabolites of a potent and irreversible peptidomimetic inhibitor of rhinovirus 3C protease. Drug Metab Dispos 2001 Zhang KE;Hee B;Lee CA;Liang B;Potts BC View More
11367747 [Effect of activities of vagi and sympathetic nervous system on heart rate variability]. Sheng Li Xue Bao 1998 Li L;Zhu JW;Cao YX;Li P View More
11378491 Rapid multiserotype detection of human rhinoviruses on optically coated silicon surfaces. J Clin Virol 2001 Ostroff R;Ettinger A;La H;Rihanek M;Zalman L;Meador J 3rd;Patick AK;Worland S;Polisky B View More
11414203 MBP fusion protein with a viral protease cleavage site: one-step cleavage/purification of insoluble proteins. Biotechniques 2001 Alexandrov A;Dutta K;Pascal SM View More
11548209 Protease inhibitors as potential antiviral agents for the treatment of picornaviral infections. Prog Drug Res 2001 Wang QM View More
11591501 Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2001 Webber SE;Marakovits JT;Dragovich PS;Prins TJ;Zhou R;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Srinivasan B;Moran T;Ford CE;Brothers MA;Harr JE;Meador JW 3rd;Ferre RA;Worland ST View More
11713272 Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation. Mol Cell Biol 2001 Kruger M;Beger C;Welch PJ;Barber JR;Manns MP;Wong-Staal F View More
11720861 Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues. Bioorg Med Chem Lett 2001 Singh SB;Graham PL;Reamer RA;Cordingley MG View More
11858991 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. Part 7: structure-activity studies of bicyclic 2-pyridone-containing peptidomimetics. Bioorg Med Chem Lett 2002 Dragovich PS;Prins TJ;Zhou R;Johnson TO;Brown EL;Maldonado FC;Fuhrman SA;Zalman LS;Patick AK;Matthews DA;Hou X;Meador JW;Ferre RA;Worland ST View More
11865407 Rhinovirus infection increases 5-lipoxygenase and cyclooxygenase-2 in bronchial biopsy specimens from nonatopic subjects. J Infect Dis 2002 Seymour ML;Gilby N;Bardin PG;Fraenkel DJ;Sanderson G;Penrose JF;Holgate ST;Johnston SL;Sampson AP View More
11900346 Peptidyl diazomethyl ketones inhibit the human rhinovirus 3C protease: effect on virus yield by partial block of P3 polyprotein processing. Antivir Chem Chemother 2001 Murray MA;Janc JW;Venkatraman S;Babe LM View More
11911365 Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C. RNA 2002 Zell R;Sidigi K;Bucci E;Stelzner A;Gorlach M View More
11931615 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 6. Structure-activity studies of orally bioavailable, 2-pyridone-containing peptidomimetics. J Med Chem 2002 Dragovich PS;Prins TJ;Zhou R;Brown EL;Maldonado FC;Fuhrman SA;Zalman LS;Tuntland T;Lee CA;Patick AK;Matthews DA;Hendrickson TF;Kosa MB;Liu B;Batugo MR;Gleeson JP;Sakata SK;Chen L;Guzman MC;Meador JW 3rd;Ferre RA;Worland ST View More
11966457 Thiol-dependent enzymes and their inhibitors: a review. Curr Med Chem 2002 Leung-Toung R;Li W;Tam TF;Karimian K View More
11985469 Structure-based design of a parallel synthetic array directed toward the discovery of irreversible inhibitors of human rhinovirus 3C protease. J Med Chem 2002 Johnson TO;Hua Y;Luu HT;Brown EL;Chan F;Chu SS;Dragovich PS;Eastman BW;Ferre RA;Fuhrman SA;Hendrickson TF;Maldonado FC;Matthews DA;Meador JW 3rd;Patick AK;Reich SH;Skalitzky DJ;Worland ST;Yang M;Zalman LS View More
12133721 Recent advances in the synthesis, design and selection of cysteine protease inhibitors. Curr Opin Chem Biol 2002 Hernandez AA;Roush WR View More
12228254 Recognition of eukaryotic initiation factor 4G isoforms by picornaviral proteinases. J Biol Chem 2002 Foeger N;Glaser W;Skern T View More
12370021 Inhibition of cysteine protease activity by NO-donors. Curr Protein Pept Sci 2001 Ascenzi P;Salvati L;Bolognesi M;Colasanti M;Polticelli F;Venturini G View More
12525179 The unusual catalytic triad of poliovirus protease 3C. Biochemistry 2003 Sarkany Z;Polgar L View More
12653165 Increased aeroallergen-specific interleukin-4-producing T cells in asthmatic adults. Clin Exp Allergy 2002 Pala P;Message SD;Johnston SL;Openshaw PJ View More
12663811 The processing of eIF4GI by human rhinovirus type 2 2A(pro): relationship to self-cleavage and role of zinc. J Virol 2003 Glaser W;Triendl A;Skern T View More
12663812 Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different. J Virol 2003 Gradi A;Svitkin YV;Sommergruber W;Imataka H;Morino S;Skern T;Sonenberg N View More
12746549 Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. Science 2003 Anand K;Ziebuhr J;Wadhwani P;Mesters JR;Hilgenfeld R View More
12766405 Backbone 1H, 15N and 13C assignments for the human rhinovirus 3C protease (serotype 14). J Biomol NMR 2003 Bjorndahl TC;Monzavi H;Wishart DS View More
12791690 Human rhinovirus 2 2Apro recognition of eukaryotic initiation factor 4GI. Involvement of an exosite. J Biol Chem 2003 Foeger N;Schmid EM;Skern T View More
12921996 Encephalomyocarditis virus (EMCV) proteins 2A and 3BCD localize to nuclei and inhibit cellular mRNA transcription but not rRNA transcription. Virus Res 2003 Aminev AG;Amineva SP;Palmenberg AC View More
1310193 Characterization of the roles of conserved cysteine and histidine residues in poliovirus 2A protease. Virology 1992 Yu SF;Lloyd RE View More
1316450 Determinants of substrate recognition by poliovirus 2A proteinase. J Virol 1992 Hellen CU;Lee CK;Wimmer E View More
1325156 Using proteinase trapping to detect revertants of inactive rhinoviral 2A proteinase mutants. Biol Chem Hoppe Seyler 1992 Luderer M;Liebig HD;Sommergruber W;Blaas D;Kuechler E;Skern T View More
1331062 Cleavage specificity on synthetic peptide substrates of human rhinovirus 2 proteinase 2A. J Biol Chem 1992 Sommergruber W;Ahorn H;Zophel A;Maurer-Fogy I;Fessl F;Schnorrenberg G;Liebig HD;Blaas D;Kuechler E;Skern T View More
14505664 Synthesis and evaluation of tripeptidyl alpha-ketoamides as human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2003 Chen SH;Lamar J;Victor F;Snyder N;Johnson R;Heinz BA;Wakulchik M;Wang QM View More
14521419 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics. J Med Chem 2003 Dragovich PS;Prins TJ;Zhou R;Johnson TO;Hua Y;Luu HT;Sakata SK;Brown EL;Maldonado FC;Tuntland T;Lee CA;Fuhrman SA;Zalman LS;Patick AK;Matthews DA;Wu EY;Guo M;Borer BC;Nayyar NK;Moran T;Chen L;Rejto PA;Rose PW;Guzman MC;Dovalsantos EZ;Lee S;McGee K;Mohajeri M;Liese A;Tao J;Kosa MB;Liu B;Batugo MR;Gleeson JP;Wu ZP;Liu J;Meador JW 3rd;Ferre RA View More
14605258 Rhinovirus 16 3C protease induces interleukin-8 and granulocyte-macrophage colony-stimulating factor expression in human bronchial epithelial cells. Pediatr Res 2004 Funkhouser AW;Kang JA;Tan A;Li J;Zhou L;Abe MK;Solway J;Hershenson MB View More
15003865 NuMA and nuclear lamins are cleaved during viral infection--inhibition of caspase activity prevents cleavage and rescues HeLa cells from measles virus-induced but not from rhinovirus 1B-induced cell death. Virology 2004 Taimen P;Berghall H;Vainionpaa R;Kallajoki M View More
15080921 Exploring the binding mechanism of the main proteinase in SARS-associated coronavirus and its implication to anti-SARS drug design. Bioorg Med Chem 2004 Zhang XW;Yap YL View More
15168795 An optical thin film assay incorporating rhinovirus protease inhibitors as detector reagents. Antiviral Res 2004 Ettinger A;Ostroff R;Rhihanek M;Dragovich PS;Zalman LS;Patick AK;Prins TJ;Fuhrman SA;Brown EL;Worland ST;Polisky B View More
15320724 Inhibitors of 3C cysteine proteinases from Picornaviridae. Curr Top Med Chem 2004 Lall MS;Jain RP;Vederas JC View More
15448360 Rhinovirus 3C protease precursors 3CD and 3CD\' localize to the nuclei of infected cells. J Gen Virol 2004 Amineva SP;Aminev AG;Palmenberg AC;Gern JE View More
15673742 Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor. Antimicrob Agents Chemother 2005 Binford SL;Maldonado F;Brothers MA;Weady PT;Zalman LS;Meador JW 3rd;Matthews DA;Patick AK View More
15722530 Phylogenetic analysis of human rhinovirus capsid protein VP1 and 2A protease coding sequences confirms shared genus-like relationships with human enteroviruses. J Gen Virol 2005 Laine P;Savolainen C;Blomqvist S;Hovi T View More
15814817 A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA. Nucleic Acids Res 2005 Ihle Y;Ohlenschlager O;Hafner S;Duchardt E;Zacharias M;Seitz S;Zell R;Ramachandran R;Gorlach M View More
15917520 In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease. Antimicrob Agents Chemother 2005 Patick AK;Brothers MA;Maldonado F;Binford S;Maldonado O;Fuhrman S;Petersen A;Smith GJ 3rd;Zalman LS;Burns-Naas LA;Tran JQ View More
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16415022 Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease. J Virol 2006 Baxter NJ;Roetzer A;Liebig HD;Sedelnikova SE;Hounslow AM;Skern T;Waltho JP View More
16510461 Carbocisteine inhibits rhinovirus infection in human tracheal epithelial cells. Eur Respir J 2006 Yasuda H;Yamaya M;Sasaki T;Inoue D;Nakayama K;Yamada M;Asada M;Yoshida M;Suzuki T;Nishimura H;Sasaki H View More
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16759084 Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors. J Med Chem 2006 Zhou L;Liu Y;Zhang W;Wei P;Huang C;Pei J;Yuan Y;Lai L View More
16973565 An antiviral peptide inhibitor that is active against picornavirus 2A proteinases but not cellular caspases. J Virol 2006 Deszcz L;Cencic R;Sousa C;Kuechler E;Skern T View More
17007846 Defining residues involved in human rhinovirus 2A proteinase substrate recognition. FEBS Lett 2006 Sousa C;Schmid EM;Skern T View More
17267501 MDA-5 is cleaved in poliovirus-infected cells. J Virol 2007 Barral PM;Morrison JM;Drahos J;Gupta P;Sarkar D;Fisher PB;Racaniello VR View More
17305557 Human rhinovirus 3C protease as a potential target for the development of antiviral agents. Curr Protein Pept Sci 2007 Wanga QM;Chen SH View More
17374764 PDTC inhibits picornavirus polyprotein processing and RNA replication by transporting zinc ions into cells. J Gen Virol 2007 Lanke K;Krenn BM;Melchers WJG;Seipelt J;van Kuppeveld FJM View More
17395640 The leader region of Laminin B1 mRNA confers cap-independent translation. Nucleic Acids Res 2007 Petz M;Kozina D;Huber H;Siwiec T;Seipelt J;Sommergruber W;Mikulits W View More
17485072 Development of potent inhibitors of the coxsackievirus 3C protease. Biochem Biophys Res Commun 2007 Lee ES;Lee WG;Yun SH;Rho SH;Im I;Yang ST;Sellamuthu S;Lee YJ;Kwon SJ;Park OK;Jeon ES;Park WJ;Kim YC View More
17908951 In vitro resistance study of rupintrivir, a novel inhibitor of human rhinovirus 3C protease. Antimicrob Agents Chemother 2007 Binford SL;Weady PT;Maldonado F;Brothers MA;Matthews DA;Patick AK View More
17944485 NMR solution structures of the apo and peptide-inhibited human rhinovirus 3C protease (Serotype 14): structural and dynamic comparison. Biochemistry 2007 Bjorndahl TC;Andrew LC;Semenchenko V;Wishart DS View More
18248816 New anti-viral drugs for the treatment of the common cold. Bioorg Med Chem 2008 Maugeri C;Alisi MA;Apicella C;Cellai L;Dragone P;Fioravanzo E;Florio S;Furlotti G;Mangano G;Ombrato R;Luisi R;Pompei R;Rincicotti V;Russo V;Vitiello M;Cazzolla N View More
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18572216 Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases. Virology 2008 de Breyne S;Bonderoff JM;Chumakov KM;Lloyd RE;Hellen CU View More
18583140 Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents. Bioorg Med Chem 2008 Kuo CJ;Shie JJ;Fang JM;Yen GR;Hsu JT;Liu HG;Tseng SN;Chang SC;Lee CY;Shih SR;Liang PH View More
18647315 Rhinovirus infection and house dust mite exposure synergize in inducing bronchial epithelial cell interleukin-8 release. Clin Exp Allergy 2008 Bossios A;Gourgiotis D;Skevaki CL;Saxoni-Papageorgiou P;Lotvall J;Psarras S;Karpathios T;Constandopoulos AG;Johnston SL;Papadopoulos NG View More
19048198 Viral protease inhibitors. Handb Exp Pharmacol 2009 Anderson J;Schiffer C;Lee SK;Swanstrom R View More
19211759 Proteinase 2Apro is essential for enterovirus replication in type I interferon-treated cells. J Virol 2009 Morrison JM;Racaniello VR View More
19268541 A picornaviral loop-to-loop replication complex. J Struct Biol 2009 Claridge JK;Headey SJ;Chow JY;Schwalbe M;Edwards PJ;Jeffries CM;Venugopal H;Trewhella J;Pascal SM View More
19333433 Over-expression, rapid preparation and some properties of c-terminal BARc region in PICK1. Int J Mol Sci 2009 Xiao H;Shi Y;Yuan J;Huang Y;Wang J View More
19403669 Rhinovirus 3C protease can localize in the nucleus and alter active and passive nucleocytoplasmic transport. J Virol 2009 Ghildyal R;Jordan B;Li D;Dagher H;Bardin PG;Gern JE;Jans DA View More
19457455 Robust production of a peptide library using methodological synchronization. Protein Expr Purif 2009 Huber KL;Olson KD;Hardy JA View More
19464175 Structure-activity relationships of heteroaromatic esters as human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2009 Im I;Lee ES;Choi SJ;Lee JY;Kim YC View More
19628239 RIG-I is cleaved during picornavirus infection. Virology 2009 Barral PM;Sarkar D;Fisher PB;Racaniello VR View More
20021285 Picornaviral 3C protease inhibitors and the dual 3C protease/coronaviral 3C-like protease inhibitors. Expert Opin Ther Pat 2010 Wang HM;Liang PH View More
20066739 Rupintrivir is a promising candidate for treating severe cases of Enterovirus-71 infection. World J Gastroenterol 2010 Zhang XN;Song ZG;Jiang T;Shi BS;Hu YW;Yuan ZH View More
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20622012 Specific cleavage of the nuclear pore complex protein Nup62 by a viral protease. J Biol Chem 2010 Park N;Skern T;Gustin KE View More
20713300 Are rhinoviral proteinases responsible for mixed T(H)1 and T(H)2 immunity in chronic obstructive pulmonary disease? J Allergy Clin Immunol 2010 Upham JW;Pritchard A View More
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21543871 Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 Amacher JF;Cushing PR;Weiner JA;Madden DR View More
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21605680 Production and single-step purification of EGFP and a biotinylated version of the Human Rhinovirus 14 3C protease. Protein Expr Purif 2011 Youell J;Fordham D;Firman K View More
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21664926 Homology modeling, docking, molecular dynamics simulation, and structural analyses of coxsakievirus B3 2A protease: an enzyme involved in the pathogenesis of inflammatory myocarditis. Int J Biol Macromol 2011 Maghsoudi AH;Khodagholi F;Hadi-Alijanvand H;Esfandiarei M;Sabbaghian M;Zakeri Z;Shaerzadeh F;Abtahi S;Maghsoudi N View More
21795339 Enterovirus 71 and coxsackievirus A16 3C proteases: binding to rupintrivir and their substrates and anti-hand, foot, and mouth disease virus drug design. J Virol 2011 Lu G;Qi J;Chen Z;Xu X;Gao F;Lin D;Qian W;Liu H;Jiang H;Yan J;Gao GF View More
21813612 Crystal structures of enterovirus 71 3C protease complexed with rupintrivir reveal the roles of catalytically important residues. J Virol 2011 Wang J;Fan T;Yao X;Wu Z;Guo L;Lei X;Wang J;Wang M;Jin Q;Cui S View More
21835784 Structural basis for antiviral inhibition of the main protease, 3C, from human enterovirus 93. J Virol 2011 Costenaro L;Kaczmarska Z;Arnan C;Janowski R;Coutard B;Sola M;Gorbalenya AE;Norder H;Canard B;Coll M View More
21835805 Differential processing of nuclear pore complex proteins by rhinovirus 2A proteases from different species and serotypes. J Virol 2011 Watters K;Palmenberg AC View More
21936817 Recent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery. Biochem Soc Trans 2011 Ramajayam R;Tan KP;Liang PH View More
22072773 Ex vivo and in vivo inhibition of human rhinovirus replication by a new pseudosubstrate of viral 2A protease. J Virol 2012 Falah N;Violot S;Decimo D;Berri F;Foucault-Grunenwald ML;Ohlmann T;Schuffenecker I;Morfin F;Lina B;Riteau B;Cortay JC View More
22687728 [Expression and role of sugar chains on airway mucus during the exacerbation of airway inflammation]. Yakugaku Zasshi 2012 Ishibashi Y;Inouye Y;Taniguchi A View More
22763202 A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors. Bioorg Med Chem Lett 2012 Schunemann K;Connelly S;Kowalczyk R;Sperry J;Wilson IA;Fraser JD;Brimble MA View More
22865380 Blocking human enterovirus 71 replication by targeting viral 2A protease. J Antimicrob Chemother 2012 Falah N;Montserret R;Lelogeais V;Schuffenecker I;Lina B;Cortay JC;Violot S View More
23131833 Picornavirus modification of a host mRNA decay protein. mBio 2012 Rozovics JM;Chase AJ;Cathcart AL;Chou W;Gershon PD;Palusa S;Wilusz J;Semler BL View More
23164665 Nickel-regulated heart rate variability: the roles of oxidative stress and inflammation. Toxicol Appl Pharmacol 2013 Chuang HC;Hsueh TW;Chang CC;Hwang JS;Chuang KJ;Yan YH;Cheng TJ View More
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