Title | Non-covalent inhibitors of rhinovirus 3C protease. | ||
Author | Baxter, Andrew; Chambers, Mark; Edfeldt, Fredrik; Edman, Karl; Freeman, Adrian; Johansson, Cristian; King, Sarah; Morley, Andy; Petersen, Jens; Rawlins, Phil; Spadola, Loredana; Thong, Bob; Van de Poel, Herve; Williams, Nicola | ||
Journal | Bioorg Med Chem Lett | Publication Year/Month | 2011-Jan |
PMID | 21183345 | PMCID | -N/A- |
Affiliation | 1.AstraZeneca, R&D Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, UK. |
The first known non-covalent inhibitors of rhinovirus 3C protease (3CP) have been identified through fragment based screening and hit identification activities.