PMID Title Journal Publication Year Author View in RVdb
10098667 Design, synthesis, and evaluation of azapeptides as substrates and inhibitors for human rhinovirus 3C protease. Bioorg Med Chem Lett 1999 Venkatraman S;Kong J;Nimkar S;Wang QM;Aube J;Hanzlik RP View More
10197964 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. J Med Chem 1999 Dragovich PS;Prins TJ;Zhou R;Fuhrman SA;Patick AK;Matthews DA;Ford CE;Meador JW 3rd;Ferre RA;Worland ST View More
10197965 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements. J Med Chem 1999 Dragovich PS;Prins TJ;Zhou R;Webber SE;Marakovits JT;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Ford CE;Burke BJ;Rejto PA;Hendrickson TF;Tuntland T;Brown EL;Meador JW 3rd;Ferre RA;Harr JE;Kosa MB;Worland ST View More
10224078 Identification and characterization of human rhinovirus-14 3C protease deamidation isoform. J Biol Chem 1999 Cox GA;Johnson RB;Cook JA;Wakulchik M;Johnson MG;Villarreal EC;Wang QM View More
10353638 Solid-phase synthesis of irreversible human rhinovirus 3C protease inhibitors. Part 1: Optimization of tripeptides incorporating N-terminal amides. Bioorg Med Chem 1999 Dragovich PS;Zhou R;Skalitzky DJ;Fuhrman SA;Patick AK;Ford CE;Meador JW 3rd;Worland ST View More
10396129 Protease inhibitors as potential antiviral agents for the treatment of picornaviral infections. Prog Drug Res 1999 Wang QM View More
10465543 Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids. Bioorg Med Chem Lett 1999 Dragovich PS;Webber SE;Prins TJ;Zhou R;Marakovits JT;Tikhe JG;Fuhrman SA;Patick AK;Matthews DA;Ford CE;Brown EL;Binford SL;Meador JW 3rd;Ferre RA;Worland ST View More
10500114 Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes. Proc Natl Acad Sci U S A 1999 Matthews DA;Dragovich PS;Webber SE;Fuhrman SA;Patick AK;Zalman LS;Hendrickson TF;Love RA;Prins TJ;Marakovits JT;Zhou R;Tikhe J;Ford CE;Meador JW;Ferre RA;Brown EL;Binford SL;Brothers MA;DeLisle DM;Worland ST View More
10507325 The structures of picornaviral proteinases. Virus Res 1999 Seipelt J;Guarne A;Bergmann E;James M;Sommergruber W;Fita I;Skern T View More
10508022 In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease. Antimicrob Agents Chemother 1999 Patick AK;Binford SL;Brothers MA;Jackson RL;Ford CE;Diem MD;Maldonado F;Dragovich PS;Zhou R;Prins TJ;Fuhrman SA;Meador JW;Zalman LS;Matthews DA;Worland ST View More
10636240 Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2000 Dragovich PS;Zhou R;Webber SE;Prins TJ;Kwok AK;Okano K;Fuhrman SA;Zalman LS;Maldonado FC;Brown EL;Meador JW 3rd;Patick AK;Ford CE;Brothers MA;Binford SL;Matthews DA;Ferre RA;Worland ST View More
10702798 Initiation of Apaf-1 translation by internal ribosome entry. Oncogene 2000 Coldwell MJ;Mitchell SA;Stoneley M;MacFarlane M;Willis AE View More
10770757 Inhibition of human rhinovirus-induced cytokine production by AG7088, a human rhinovirus 3C protease inhibitor. Antimicrob Agents Chemother 2000 Zalman LS;Brothers MA;Dragovich PS;Zhou R;Prins TJ;Worland ST;Patick AK View More
10794684 Substituted benzamide inhibitors of human rhinovirus 3C protease: structure-based design, synthesis, and biological evaluation. J Med Chem 2000 Reich SH;Johnson T;Wallace MB;Kephart SE;Fuhrman SA;Worland ST;Matthews DA;Hendrickson TF;Chan F;Meador J 3rd;Ferre RA;Brown EL;DeLisle DM;Patick AK;Binford SL;Ford CE View More
10921773 A novel method of aligning molecules by local surface shape similarity. J Comput Aided Mol Des 2000 Cosgrove DA;Bayada DM;Johnson AP View More
10950388 Antiviral therapy for enteroviruses and rhinoviruses. Antivir Chem Chemother 2000 Rotbart HA View More
10999479 S-nitrosothiols as novel, reversible inhibitors of human rhinovirus 3C protease. Bioorg Med Chem Lett 2000 Xian M;Wang QM;Chen X;Wang K;Wang PG View More
11118371 Complete nucleotide sequence of the chiba virus genome and functional expression of the 3C-like protease in Escherichia coli. Virology 2000 Someya Y;Takeda N;Miyamura T View More
11162821 Activation of human rhinovirus-14 3C protease. Virology 2001 Wang QM;Johnson RB View More
11166856 The treatment of rhinovirus infections: progress and potential. Antiviral Res 2001 Turner RB View More
11249711 AG-7088 Pfizer. Curr Opin Investig Drugs 2000 Witherell G View More
11274152 Disruption of the interaction of mammalian protein synthesis eukaryotic initiation factor 4B with the poly(A)-binding protein by caspase- and viral protease-mediated cleavages. J Biol Chem 2001 Bushell M;Wood W;Carpenter G;Pain VM;Morley SJ;Clemens MJ View More
11302940 Liquid chromatography-mass spectrometry and liquid chromatography-NMR characterization of in vitro metabolites of a potent and irreversible peptidomimetic inhibitor of rhinovirus 3C protease. Drug Metab Dispos 2001 Zhang KE;Hee B;Lee CA;Liang B;Potts BC View More
11313462 Protein factor requirements of the Apaf-1 internal ribosome entry segment: roles of polypyrimidine tract binding protein and upstream of N-ras. Mol Cell Biol 2001 Mitchell SA;Brown EC;Coldwell MJ;Jackson RJ;Willis AE View More
11378491 Rapid multiserotype detection of human rhinoviruses on optically coated silicon surfaces. J Clin Virol 2001 Ostroff R;Ettinger A;La H;Rihanek M;Zalman L;Meador J 3rd;Patick AK;Worland S;Polisky B View More
11414203 MBP fusion protein with a viral protease cleavage site: one-step cleavage/purification of insoluble proteins. Biotechniques 2001 Alexandrov A;Dutta K;Pascal SM View More
11548209 Protease inhibitors as potential antiviral agents for the treatment of picornaviral infections. Prog Drug Res 2001 Wang QM View More
11591501 Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2001 Webber SE;Marakovits JT;Dragovich PS;Prins TJ;Zhou R;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Srinivasan B;Moran T;Ford CE;Brothers MA;Harr JE;Meador JW 3rd;Ferre RA;Worland ST View More
11681658 Characterization of nasal spray pumps and deposition pattern in a replica of the human nasal airway. J Aerosol Med 2001 Cheng YS;Holmes TD;Gao J;Guilmette RA;Li S;Surakitbanharn Y;Rowlings C View More
11687118 Heated, humidified air for the common cold. Cochrane Database Syst Rev 2001 Singh M View More
11713272 Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation. Mol Cell Biol 2001 Kruger M;Beger C;Welch PJ;Barber JR;Manns MP;Wong-Staal F View More
11720861 Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues. Bioorg Med Chem Lett 2001 Singh SB;Graham PL;Reamer RA;Cordingley MG View More
11725622 Otitis media in Greenland. Studies on historical, epidemiological, microbiological, and immunological aspects. Int J Circumpolar Health 2001 Homoe P View More
11844293 Effects of menstrual cycle on cardiac autonomic innervation as assessed by heart rate variability. Ann Noninvasive Electrocardiol 2002 Yildirir A;Kabakci G;Akgul E;Tokgozoglu L;Oto A View More
11858991 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. Part 7: structure-activity studies of bicyclic 2-pyridone-containing peptidomimetics. Bioorg Med Chem Lett 2002 Dragovich PS;Prins TJ;Zhou R;Johnson TO;Brown EL;Maldonado FC;Fuhrman SA;Zalman LS;Patick AK;Matthews DA;Hou X;Meador JW;Ferre RA;Worland ST View More
11900346 Peptidyl diazomethyl ketones inhibit the human rhinovirus 3C protease: effect on virus yield by partial block of P3 polyprotein processing. Antivir Chem Chemother 2001 Murray MA;Janc JW;Venkatraman S;Babe LM View More
11911365 Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C. RNA 2002 Zell R;Sidigi K;Bucci E;Stelzner A;Gorlach M View More
11931615 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 6. Structure-activity studies of orally bioavailable, 2-pyridone-containing peptidomimetics. J Med Chem 2002 Dragovich PS;Prins TJ;Zhou R;Brown EL;Maldonado FC;Fuhrman SA;Zalman LS;Tuntland T;Lee CA;Patick AK;Matthews DA;Hendrickson TF;Kosa MB;Liu B;Batugo MR;Gleeson JP;Sakata SK;Chen L;Guzman MC;Meador JW 3rd;Ferre RA;Worland ST View More
11985469 Structure-based design of a parallel synthetic array directed toward the discovery of irreversible inhibitors of human rhinovirus 3C protease. J Med Chem 2002 Johnson TO;Hua Y;Luu HT;Brown EL;Chan F;Chu SS;Dragovich PS;Eastman BW;Ferre RA;Fuhrman SA;Hendrickson TF;Maldonado FC;Matthews DA;Meador JW 3rd;Patick AK;Reich SH;Skalitzky DJ;Worland ST;Yang M;Zalman LS View More
12163876 Apparent rarity of cryptosporidiosis in human immunodeficiency virus (HIV)-related diarrhoea in Enugu, South-Eastern, Nigeria. Niger Postgrad Med J 2002 Nwokediuko SC;Bojuwoye BJ;Onyenekwe B View More
12525179 The unusual catalytic triad of poliovirus protease 3C. Biochemistry 2003 Sarkany Z;Polgar L View More
12719769 Heart rate variability and endogenous sex hormones during the menstrual cycle in young women. Exp Physiol 2003 Leicht AS;Hirning DA;Allen GD View More
12746549 Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. Science 2003 Anand K;Ziebuhr J;Wadhwani P;Mesters JR;Hilgenfeld R View More
12766405 Backbone 1H, 15N and 13C assignments for the human rhinovirus 3C protease (serotype 14). J Biomol NMR 2003 Bjorndahl TC;Monzavi H;Wishart DS View More
12921996 Encephalomyocarditis virus (EMCV) proteins 2A and 3BCD localize to nuclei and inhibit cellular mRNA transcription but not rRNA transcription. Virus Res 2003 Aminev AG;Amineva SP;Palmenberg AC View More
1331062 Cleavage specificity on synthetic peptide substrates of human rhinovirus 2 proteinase 2A. J Biol Chem 1992 Sommergruber W;Ahorn H;Zophel A;Maurer-Fogy I;Fessl F;Schnorrenberg G;Liebig HD;Blaas D;Kuechler E;Skern T View More
14505664 Synthesis and evaluation of tripeptidyl alpha-ketoamides as human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2003 Chen SH;Lamar J;Victor F;Snyder N;Johnson R;Heinz BA;Wakulchik M;Wang QM View More
14521419 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics. J Med Chem 2003 Dragovich PS;Prins TJ;Zhou R;Johnson TO;Hua Y;Luu HT;Sakata SK;Brown EL;Maldonado FC;Tuntland T;Lee CA;Fuhrman SA;Zalman LS;Patick AK;Matthews DA;Wu EY;Guo M;Borer BC;Nayyar NK;Moran T;Chen L;Rejto PA;Rose PW;Guzman MC;Dovalsantos EZ;Lee S;McGee K;Mohajeri M;Liese A;Tao J;Kosa MB;Liu B;Batugo MR;Gleeson JP;Wu ZP;Liu J;Meador JW 3rd;Ferre RA View More
14605258 Rhinovirus 16 3C protease induces interleukin-8 and granulocyte-macrophage colony-stimulating factor expression in human bronchial epithelial cells. Pediatr Res 2004 Funkhouser AW;Kang JA;Tan A;Li J;Zhou L;Abe MK;Solway J;Hershenson MB View More
15080921 Exploring the binding mechanism of the main proteinase in SARS-associated coronavirus and its implication to anti-SARS drug design. Bioorg Med Chem 2004 Zhang XW;Yap YL View More
15106160 Heated, humidified air for the common cold. Cochrane Database Syst Rev 2004 Singh M View More
15110922 Heart rate variability in premenstrual dysphoric disorder. Psychoneuroendocrinology 2004 Landen M;Wennerblom B;Tygesen H;Modigh K;Sorvik K;Ysander C;Ekman A;Nissbrandt H;Olsson M;Eriksson E View More
15168795 An optical thin film assay incorporating rhinovirus protease inhibitors as detector reagents. Antiviral Res 2004 Ettinger A;Ostroff R;Rhihanek M;Dragovich PS;Zalman LS;Patick AK;Prins TJ;Fuhrman SA;Brown EL;Worland ST;Polisky B View More
15170592 Selective human enterovirus and rhinovirus inhibitors: An overview of capsid-binding and protease-inhibiting molecules. Med Res Rev 2004 Shih SR;Chen SJ;Hakimelahi GH;Liu HJ;Tseng CT;Shia KS View More
15233931 Enhanced cardiac vagal efferent activity does not explain training-induced bradycardia. Auton Neurosci 2004 Scott AS;Eberhard A;Ofir D;Benchetrit G;Dinh TP;Calabrese P;Lesiuk V;Perrault H View More
15448360 Rhinovirus 3C protease precursors 3CD and 3CD\' localize to the nuclei of infected cells. J Gen Virol 2004 Amineva SP;Aminev AG;Palmenberg AC;Gern JE View More
15578974 Recent advances in rhinovirus therapeutics. Curr Drug Targets Infect Disord 2004 Charles CH;Yelmene M;Luo GX View More
15592828 Inhibitors of virus replication: recent developments and prospects. Appl Microbiol Biotechnol 2005 Magden J;Kaariainen L;Ahola T View More
15673742 Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor. Antimicrob Agents Chemother 2005 Binford SL;Maldonado F;Brothers MA;Weady PT;Zalman LS;Meador JW 3rd;Matthews DA;Patick AK View More
15814817 A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA. Nucleic Acids Res 2005 Ihle Y;Ohlenschlager O;Hafner S;Duchardt E;Zacharias M;Seitz S;Zell R;Ramachandran R;Gorlach M View More
15917520 In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease. Antimicrob Agents Chemother 2005 Patick AK;Brothers MA;Maldonado F;Binford S;Maldonado O;Fuhrman S;Petersen A;Smith GJ 3rd;Zalman LS;Burns-Naas LA;Tran JQ View More
15921461 Human rhinovirus 3C protease: generation of pharmacophore models for peptidic and nonpeptidic inhibitors and their application in virtual screening. J Chem Inf Model 2005 Steindl T;Laggner C;Langer T View More
15931543 Detection of secretory IgM in tears during rhino-conjunctivitis. Graefes Arch Clin Exp Ophthalmol 2005 Bours J;Reitz C;Strobel J;Breipohl W View More
15956547 Pyrrolidine dithiocarbamate reduces coxsackievirus B3 replication through inhibition of the ubiquitin-proteasome pathway. J Virol 2005 Si X;McManus BM;Zhang J;Yuan J;Cheung C;Esfandiarei M;Suarez A;Morgan A;Luo H View More
16279553 [Rhinovirus diseases: pathogenesis, diagnostics and treatment]. Zh Mikrobiol Epidemiol Immunobiol 2005 Faizuloev EB;Nikonova AA;Zverev VV View More
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16611122 Current status of anti-picornavirus therapies. Curr Pharm Des 2006 Barnard DL View More
16675037 Rhinovirus chemotherapy. Antiviral Res 2006 Patick AK View More
16759084 Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors. J Med Chem 2006 Zhou L;Liu Y;Zhang W;Wei P;Huang C;Pei J;Yuan Y;Lai L View More
16855975 Heated, humidified air for the common cold. Cochrane Database Syst Rev 2006 Singh M View More
17267501 MDA-5 is cleaved in poliovirus-infected cells. J Virol 2007 Barral PM;Morrison JM;Drahos J;Gupta P;Sarkar D;Fisher PB;Racaniello VR View More
17305557 Human rhinovirus 3C protease as a potential target for the development of antiviral agents. Curr Protein Pept Sci 2007 Wanga QM;Chen SH View More
17374764 PDTC inhibits picornavirus polyprotein processing and RNA replication by transporting zinc ions into cells. J Gen Virol 2007 Lanke K;Krenn BM;Melchers WJG;Seipelt J;van Kuppeveld FJM View More
17485072 Development of potent inhibitors of the coxsackievirus 3C protease. Biochem Biophys Res Commun 2007 Lee ES;Lee WG;Yun SH;Rho SH;Im I;Yang ST;Sellamuthu S;Lee YJ;Kwon SJ;Park OK;Jeon ES;Park WJ;Kim YC View More
17898077 Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs. Mol Biol Cell 2007 Cammas A;Pileur F;Bonnal S;Lewis SM;Leveque N;Holcik M;Vagner S View More
17908951 In vitro resistance study of rupintrivir, a novel inhibitor of human rhinovirus 3C protease. Antimicrob Agents Chemother 2007 Binford SL;Weady PT;Maldonado F;Brothers MA;Matthews DA;Patick AK View More
17944485 NMR solution structures of the apo and peptide-inhibited human rhinovirus 3C protease (Serotype 14): structural and dynamic comparison. Biochemistry 2007 Bjorndahl TC;Andrew LC;Semenchenko V;Wishart DS View More
18190777 A mammalian cell-based reverse two-hybrid system for functional analysis of 3C viral protease of human enterovirus 71. Anal Biochem 2008 Lee JC;Shih SR;Chang TY;Tseng HY;Shih YF;Yen KJ;Chen WC;Shie JJ;Fang JM;Liang PH;Chao YS;Hsu JT View More
18248816 New anti-viral drugs for the treatment of the common cold. Bioorg Med Chem 2008 Maugeri C;Alisi MA;Apicella C;Cellai L;Dragone P;Fioravanzo E;Florio S;Furlotti G;Mangano G;Ombrato R;Luisi R;Pompei R;Rincicotti V;Russo V;Vitiello M;Cazzolla N View More
18381747 Selective inhibitors of picornavirus replication. Med Res Rev 2008 De Palma AM;Vliegen I;De Clercq E;Neyts J View More
18572216 Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases. Virology 2008 de Breyne S;Bonderoff JM;Chumakov KM;Lloyd RE;Hellen CU View More
18582607 Reduced parasympathetic activity during sleep in the symptomatic phase of severe premenstrual syndrome. J Psychosom Res 2008 Baker FC;Colrain IM;Trinder J View More
18583140 Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents. Bioorg Med Chem 2008 Kuo CJ;Shie JJ;Fang JM;Yen GR;Hsu JT;Liu HG;Tseng SN;Chang SC;Lee CY;Shih SR;Liang PH View More
19048198 Viral protease inhibitors. Handb Exp Pharmacol 2009 Anderson J;Schiffer C;Lee SK;Swanstrom R View More
19102616 Increased interestingness of extraneous details in a multimedia science presentation leads to decreased learning. J Exp Psychol Appl 2008 Mayer RE;Griffith E;Jurkowitz IT;Rothman D View More
19268541 A picornaviral loop-to-loop replication complex. J Struct Biol 2009 Claridge JK;Headey SJ;Chow JY;Schwalbe M;Edwards PJ;Jeffries CM;Venugopal H;Trewhella J;Pascal SM View More
19333433 Over-expression, rapid preparation and some properties of c-terminal BARc region in PICK1. Int J Mol Sci 2009 Xiao H;Shi Y;Yuan J;Huang Y;Wang J View More
19403669 Rhinovirus 3C protease can localize in the nucleus and alter active and passive nucleocytoplasmic transport. J Virol 2009 Ghildyal R;Jordan B;Li D;Dagher H;Bardin PG;Gern JE;Jans DA View More
19457455 Robust production of a peptide library using methodological synchronization. Protein Expr Purif 2009 Huber KL;Olson KD;Hardy JA View More
19464175 Structure-activity relationships of heteroaromatic esters as human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2009 Im I;Lee ES;Choi SJ;Lee JY;Kim YC View More
19465541 Influence of the menstrual cycle on nonlinear properties of heart rate variability in young women. Am J Physiol Heart Circ Physiol 2009 Bai X;Li J;Zhou L;Li X View More
19628239 RIG-I is cleaved during picornavirus infection. Virology 2009 Barral PM;Sarkar D;Fisher PB;Racaniello VR View More
20012447 Effect of lecturing to 200 students on heart rate variability and alpha-amylase activity. Eur J Appl Physiol 2010 Filaire E;Portier H;Massart A;Ramat L;Teixeira A View More
20021285 Picornaviral 3C protease inhibitors and the dual 3C protease/coronaviral 3C-like protease inhibitors. Expert Opin Ther Pat 2010 Wang HM;Liang PH View More
20063033 Alteration of skin laser-Doppler flux response to local cooling in gestational hypertension. Clin Auton Res 2010 Cankar K;Potocnik N;Strucl M View More
20066739 Rupintrivir is a promising candidate for treating severe cases of Enterovirus-71 infection. World J Gastroenterol 2010 Zhang XN;Song ZG;Jiang T;Shi BS;Hu YW;Yuan ZH View More
21183345 Non-covalent inhibitors of rhinovirus 3C protease. Bioorg Med Chem Lett 2011 Baxter A;Chambers M;Edfeldt F;Edman K;Freeman A;Johansson C;King S;Morley A;Petersen J;Rawlins P;Spadola L;Thong B;Van de Poel H;Williams N View More
21476202 Effect of acupuncture on heart rate variability in primary dysmenorrheic women. Am J Chin Med 2011 Kim E;Cho JH;Jung WS;Lee S;Pak SC View More
21543871 Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 Amacher JF;Cushing PR;Weiner JA;Madden DR View More
21563130 Heated, humidified air for the common cold. Cochrane Database Syst Rev 2011 Singh M;Singh M View More
21605680 Production and single-step purification of EGFP and a biotinylated version of the Human Rhinovirus 14 3C protease. Protein Expr Purif 2011 Youell J;Fordham D;Firman K View More
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21658810 Room ventilation and the risk of airborne infection transmission in 3 health care settings within a large teaching hospital. Am J Infect Control 2011 Knibbs LD;Morawska L;Bell SC;Grzybowski P View More
21767303 Characterization of 2009 H1N1 pandemic influenza in a population of Dutch children with influenza-like signs and symptoms. Acta Paediatr 2012 Smit PM;Bongers KM;Kuiper RJ;von Rosenstiel IA;Smits PH;Brandjes DP View More
21795339 Enterovirus 71 and coxsackievirus A16 3C proteases: binding to rupintrivir and their substrates and anti-hand, foot, and mouth disease virus drug design. J Virol 2011 Lu G;Qi J;Chen Z;Xu X;Gao F;Lin D;Qian W;Liu H;Jiang H;Yan J;Gao GF View More
21813612 Crystal structures of enterovirus 71 3C protease complexed with rupintrivir reveal the roles of catalytically important residues. J Virol 2011 Wang J;Fan T;Yao X;Wu Z;Guo L;Lei X;Wang J;Wang M;Jin Q;Cui S View More
21835784 Structural basis for antiviral inhibition of the main protease, 3C, from human enterovirus 93. J Virol 2011 Costenaro L;Kaczmarska Z;Arnan C;Janowski R;Coutard B;Sola M;Gorbalenya AE;Norder H;Canard B;Coll M View More
21936817 Recent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery. Biochem Soc Trans 2011 Ramajayam R;Tan KP;Liang PH View More
22432004 Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis. PLoS One 2012 Smith SB;Dampier W;Tozeren A;Brown JR;Magid-Slav M View More
22474420 The effects of green tea consumption on cardiometabolic alterations induced by experimental diabetes. Exp Diabetes Res 2012 Fiorino P;Evangelista FS;Santos F;Motter Magri FM;Delorenzi JC;Ginoza M;Farah V View More
22561416 Effects of sauna alone versus postexercise sauna baths on short-term heart rate variability in patients with untreated hypertension. J Cardiopulm Rehabil Prev 2012 Gayda M;Bosquet L;Paillard F;Garzon M;Sosner P;Juneau M;Belanger M;Nigam A View More
22677581 A prospective study of heart rate variability in endocrine surgery: surgical training increases consultant\'s mental strain. J Surg Educ 2012 Prichard RS;O'Neill CJ;Oucharek JJ;Holmes CY;Delbridge LW;Sywak MS View More
22763202 A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors. Bioorg Med Chem Lett 2012 Schunemann K;Connelly S;Kowalczyk R;Sperry J;Wilson IA;Fraser JD;Brimble MA View More
22865380 Blocking human enterovirus 71 replication by targeting viral 2A protease. J Antimicrob Chemother 2012 Falah N;Montserret R;Lelogeais V;Schuffenecker I;Lina B;Cortay JC;Violot S View More
23131833 Picornavirus modification of a host mRNA decay protein. mBio 2012 Rozovics JM;Chase AJ;Cathcart AL;Chou W;Gershon PD;Palusa S;Wilusz J;Semler BL View More
23255796 Viral proteinase requirements for the nucleocytoplasmic relocalization of cellular splicing factor SRp20 during picornavirus infections. J Virol 2013 Fitzgerald KD;Chase AJ;Cathcart AL;Tran GP;Semler BL View More
23300834 Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification. PLoS One 2012 Gawthorne JA;Reddick LE;Akpunarlieva SN;Beckham KS;Christie JM;Alto NM;Gabrielsen M;Roe AJ View More
23388726 3C protease of enterovirus 68: structure-based design of Michael acceptor inhibitors and their broad-spectrum antiviral effects against picornaviruses. J Virol 2013 Tan J;George S;Kusov Y;Perbandt M;Anemuller S;Mesters JR;Norder H;Coutard B;Lacroix C;Leyssen P;Neyts J;Hilgenfeld R View More
23395976 Differential temperature dependence of tobacco etch virus and rhinovirus 3C proteases. Anal Biochem 2013 Raran-Kurussi S;Tozser J;Cherry S;Tropea JE;Waugh DS View More
23410102 A new method to customize protein expression vectors for fast, efficient and background free parallel cloning. BMC Biotechnol 2013 Scholz J;Besir H;Strasser C;Suppmann S View More
23412071 Epidemiology of respiratory viral infection using multiplex rt-PCR in Cheonan, Korea (2006-2010). J Microbiol Biotechnol 2013 Kim JK;Jeon JS;Kim JW;Rheem I View More
23549610 The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles\' heel": current effective inhibitor targeting a 3C-like protease. Protein Cell 2013 Ren Z;Yan L;Zhang N;Guo Y;Yang C;Lou Z;Rao Z View More
23633597 Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir. Acta Crystallogr D Biol Crystallogr 2013 Wu C;Cai Q;Chen C;Li N;Peng X;Cai Y;Yin K;Chen X;Wang X;Zhang R;Liu L;Chen S;Li J;Lin T View More
23717587 Laboratory surveillance of influenza-like illness in seven teaching hospitals, South Korea: 2011-2012 season. PLoS One 2013 Noh JY;Song JY;Cheong HJ;Choi WS;Lee J;Lee JS;Wie SH;Jeong HW;Kim YK;Choi SH;Han SB;So BH;Kim H;Kim WJ View More
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9200068 Nerve growth factor antibody stimulates reactivation of ocular herpes simplex virus type 1 in latently infected rabbits. J Neurovirol 1997 Hill JM;Garza HH Jr;Helmy MF;Cook SD;Osborne PA;Johnson EM Jr;Thompson HW;Green LC;O'Callaghan RJ;Gebhardt BM View More
9328292 Expression and purification of recombinant rhinovirus 14 3CD proteinase and its comparison to the 3C proteinase. Arch Biochem Biophys 1997 Davis GJ;Wang QM;Cox GA;Johnson RB;Wakulchik M;Dotson CA;Villarreal EC View More
9344409 A continuous colorimetric assay for rhinovirus-14 3C protease using peptide p-nitroanilides as substrates. Anal Biochem 1997 Wang QM;Johnson RB;Cox GA;Villarreal EC;Loncharich RJ View More
9472614 A structural model of picornavirus leader proteinases based on papain and bleomycin hydrolase. J Gen Virol 1998 Skern T;Fita I;Guarne A View More
9559808 Dual inhibition of human rhinovirus 2A and 3C proteases by homophthalimides. Antimicrob Agents Chemother 1998 Wang QM;Johnson RB;Jungheim LN;Cohen JD;Villarreal EC View More
9651162 Synthesis and evaluation of peptidyl Michael acceptors that inactivate human rhinovirus 3C protease and inhibit virus replication. J Med Chem 1998 Kong JS;Venkatraman S;Furness K;Nimkar S;Shepherd TA;Wang QM;Aube J;Hanzlik RP View More
9667969 Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements. J Med Chem 1998 Webber SE;Okano K;Little TL;Reich SH;Xin Y;Fuhrman SA;Matthews DA;Love RA;Hendrickson TF;Patick AK;Meador JW 3rd;Ferre RA;Brown EL;Ford CE;Binford SL;Worland ST View More
9667970 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies. J Med Chem 1998 Dragovich PS;Webber SE;Babine RE;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Reich SH;Prins TJ;Marakovits JT;Littlefield ES;Zhou R;Tikhe J;Ford CE;Wallace MB;Meador JW 3rd;Ferre RA;Brown EL;Binford SL;Harr JE;DeLisle DM;Worland ST View More
9667971 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 2. Peptide structure-activity studies. J Med Chem 1998 Dragovich PS;Webber SE;Babine RE;Fuhrman SA;Patick AK;Matthews DA;Reich SH;Marakovits JT;Prins TJ;Zhou R;Tikhe J;Littlefield ES;Bleckman TM;Wallace MB;Little TL;Ford CE;Meador JW 3rd;Ferre RA;Brown EL;Binford SL;DeLisle DM;Worland ST View More
9681985 Development of in vitro peptide substrates for human rhinovirus-14 2A protease. Arch Biochem Biophys 1998 Wang QM;Johnson RB;Sommergruber W;Shepherd TA View More
9767059 Protease inhibitors as antiviral agents. Clin Microbiol Rev 1998 Patick AK;Potts KE View More
9989947 Inhibition of 3C protease from human rhinovirus strain 1B by peptidyl bromomethylketonehydrazides. Arch Biochem Biophys 1999 Kati WM;Sham HL;McCall JO;Montgomery DA;Wang GT;Rosenbrook W;Miesbauer L;Buko A;Norbeck DW View More