PMID Title Journal Publication Year Author View in RVdb
10360742 Short synthesis and anti-rhinoviral activity of imidazo[1,2-a]pyridines: the effect of acyl groups at 3-position. Bioorg Med Chem Lett 1999 Hamdouchi C;Ezquerra J;Vega JA;Vaquero JJ;Alvarez-Builla J;Heinz BA View More
10508022 In vitro antiviral activity of AG7088, a potent inhibitor of human rhinovirus 3C protease. Antimicrob Agents Chemother 1999 Patick AK;Binford SL;Brothers MA;Jackson RL;Ford CE;Diem MD;Maldonado F;Dragovich PS;Zhou R;Prins TJ;Fuhrman SA;Meador JW;Zalman LS;Matthews DA;Worland ST View More
10722493 Antiviral properties of a series of 1,6-naphthyridine and 7, 8-dihydroisoquinoline derivatives exhibiting potent activity against human cytomegalovirus. Antimicrob Agents Chemother 2000 Bedard J;May S;L'Heureux L;Stamminger T;Copsey A;Drach J;Huffman J;Chan L;Jin H;Rando RF View More
10770757 Inhibition of human rhinovirus-induced cytokine production by AG7088, a human rhinovirus 3C protease inhibitor. Antimicrob Agents Chemother 2000 Zalman LS;Brothers MA;Dragovich PS;Zhou R;Prins TJ;Worland ST;Patick AK View More
11591501 Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2001 Webber SE;Marakovits JT;Dragovich PS;Prins TJ;Zhou R;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Srinivasan B;Moran T;Ford CE;Brothers MA;Harr JE;Meador JW 3rd;Ferre RA;Worland ST View More
12951207 A disc-based quantitative carrier test method to assess the virucidal activity of chemical germicides. J Virol Methods 2003 Sattar SA;Springthorpe VS;Adegbunrin O;Zafer AA;Busa M View More
1313108 CoMFA analysis of the interactions of antipicornavirus compounds in the binding pocket of human rhinovirus-14. J Med Chem 1992 Diana GD;Kowalczyk P;Treasurywala AM;Oglesby RC;Pevear DC;Dutko FJ View More
1317142 In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviral activity. Antimicrob Agents Chemother 1992 Andries K;Dewindt B;Snoeks J;Willebrords R;van Eemeren K;Stokbroekx R;Janssen PA View More
14594825 Null mutations in a Nudix gene, ygdP, implicate an alarmone response in a novel suppression of hybrid jamming. J Bacteriol 2003 Hand NJ;Silhavy TJ View More
16358917 [Microbiologic diagnosis of acute upper respiratory tract infections]. Pol Merkur Lekarski 2005 Lopaciuk U;Pinkas J View More
1656851 Binding affinities of structurally related human rhinovirus capsid-binding compounds are related to their activities against human rhinovirus type 14. Antimicrob Agents Chemother 1991 Fox MP;McKinlay MA;Diana GD;Dutko FJ View More
17197049 Differential sensitivity of viruses to the antiviral activity of Shiga toxin 1 A subunit. Virus Res 2007 Ferens WA;Halver M;Gustin KE;Ott T;Hovde CJ View More
172632 Synthesis of 5-amino-1-(5-deoxy-beta-D-ribofuranosyl)imidazole-4-carboxamide and related 5\'-deoxyimidazole ribonucleosides. J Med Chem 1975 Srivastava PC;Newman AR;Matthews TR;Robins RK View More
17497238 Antiviral activity of arbidol against influenza A virus, respiratory syncytial virus, rhinovirus, coxsackie virus and adenovirus in vitro and in vivo. Arch Virol 2007 Shi L;Xiong H;He J;Deng H;Li Q;Zhong Q;Hou W;Cheng L;Xiao H;Yang Z View More
17908951 In vitro resistance study of rupintrivir, a novel inhibitor of human rhinovirus 3C protease. Antimicrob Agents Chemother 2007 Binford SL;Weady PT;Maldonado F;Brothers MA;Matthews DA;Patick AK View More
18046960 Isothiazole derivatives as antiviral agents. Antivir Chem Chemother 2007 Garozzo A;Cutri CC;Pannecouque C;Castro A;Guerrera F;De Clercq E View More
184281 Synthesis and antiviral and antimicrobial activity of certain 1-beta-D-ribofuranosyl-4,5-disubstituted imidazoles. J Med Chem 1976 Srivastava PC;Streeter DG;Matthews TR;Allen LB;Sidwell RW View More
1847431 4\'-Hydroxy-3-methoxyflavones with potent antipicornavirus activity. J Med Chem 1991 De Meyer N;Haemers A;Mishra L;Pandey HK;Pieters LA;Vanden Berghe DA;Vlietinck AJ View More
188604 Antirival activity of N-phenyl-N\'-arylthiourea derivatives against some Rhinoviruses. Chemotherapy 1977 Galabov AS;Velichkova EH;Vassilev GN View More
19180966 [In vitro experimental study on the effect of resveratrol against several kinds of respiroviruses]. Zhong Yao Cai 2008 Guan WD;Yang ZF;Liu N;Qin S;Zhang FX;Zhu YT View More
19237651 Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307. Antimicrob Agents Chemother 2009 De Palma AM;Thibaut HJ;van der Linden L;Lanke K;Heggermont W;Ireland S;Andrews R;Arimilli M;Al-Tel TH;De Clercq E;van Kuppeveld F;Neyts J View More
203953 [Antimicrobially effective pyridazines]. Pharmazie 1977 Limanov VE View More
20412019 Anti-human rhinovirus activity of raoulic acid from Raoulia australis. J Med Food 2010 Choi HJ;Song JH;Lim CH;Baek SH;Kwon DH View More
20937137 An RNA replication-center assay for high content image-based quantifications of human rhinovirus and coxsackievirus infections. Virol J 2010 Jurgeit A;Moese S;Roulin P;Dorsch A;Lotzerich M;Lee WM;Greber UF View More
212977 A new antirhinovirus compound, ICI 73602: structure, properties, and spectrum of activity. Ann N Y Acad Sci 1977 Swallow DL;Bucknall RA;Stanier WE;Hutchinson A;Gaskin H View More
21300110 Development of a high-throughput human rhinovirus infectivity cell-based assay for identifying antiviral compounds. J Virol Methods 2011 Phillips T;Jenkinson L;McCrae C;Thong B;Unitt J View More
21466823 Towards the design of combination therapy for the treatment of enterovirus infections. Antiviral Res 2011 Thibaut HJ;Leyssen P;Puerstinger G;Muigg A;Neyts J;De Palma AM View More
2158559 A model for compounds active against human rhinovirus-14 based on X-ray crystallography data. J Med Chem 1990 Diana GD;Treasurywala AM;Bailey TR;Oglesby RC;Pevear DC;Dutko FJ View More
2158561 Antirhinovirus activity of 6-anilino-9-benzyl-2-chloro-9H-purines. J Med Chem 1990 Kelley JL;Linn JA;Selway JW View More
2163455 Synthesis, antitumor activity, and antiviral activity of 3-substituted 3-deazacytidines and 3-substituted 3-deazauridines. J Med Chem 1990 McNamara DJ;Cook PD;Allen LB;Kehoe MJ;Holland CS;Teepe AG View More
2168152 Pathogenicity for humans of human rhinovirus type 2 mutants resistant to or dependent on chalcone Ro 09-0410. Antimicrob Agents Chemother 1990 Yasin SR;al-Nakib W;Tyrrell DA View More
22202806 Synthesis of 1,4-disubstituted mono and bis-triazolocarbo-acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine by Cu(I)-catalyzed click azide-alkyne cycloaddition. Molecules 2011 Krim J;Taourirte M;Engels JW View More
22486038 Chemical and antiviral study on alkaloids from Papaver pseudocanescens M. Pop. Z Naturforsch C J Biosci 2012 Istatkova R;Nikolaeva-Glomb L;Galabov A;Yadamsuren GO;Samdan J;Dangaa S;Philipov S View More
23388726 3C protease of enterovirus 68: structure-based design of Michael acceptor inhibitors and their broad-spectrum antiviral effects against picornaviruses. J Virol 2013 Tan J;George S;Kusov Y;Perbandt M;Anemuller S;Mesters JR;Norder H;Coutard B;Lacroix C;Leyssen P;Neyts J;Hilgenfeld R View More
23726345 Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus. Bioorg Med Chem Lett 2013 Decor A;Grand-Maitre C;Hucke O;O'Meara J;Kuhn C;Constantineau-Forget L;Brochu C;Malenfant E;Bertrand-Laperle M;Bordeleau J;Ghiro E;Pesant M;Fazal G;Gorys V;Little M;Boucher C;Bordeleau S;Turcotte P;Guo T;Garneau M;Spickler C;Gauthier A View More
23821280 A fluorescence-based high-throughput antiviral compound screening assay against respiratory syncytial virus. Methods Mol Biol 2013 Kwanten L;De Clerck B;Roymans D View More
2417545 In vitro and in vivo antipicornavirus activity of some phenoxypyridinecarbonitriles. Antimicrob Agents Chemother 1985 Kenny MT;Dulworth JK;Torney HL View More
24602790 Synthesis, biological activity and structure-activity relationship of 4,5-dimethoxybenzene derivatives inhibitor of rhinovirus 14 infection. Eur J Med Chem 2014 Roche M;Lacroix C;Khoumeri O;Franco D;Neyts J;Terme T;Leyssen P;Vanelle P View More
24885569 Antiviral activity and possible mode of action of ellagic acid identified in Lagerstroemia speciosa leaves toward human rhinoviruses. BMC Complement Altern Med 2014 Park SW;Kwon MJ;Yoo JY;Choi HJ;Ahn YJ View More
24899029 Detection of hepatitis B virus genotypic resistance mutations by coamplification at lower denaturation temperature-PCR coupled with sanger sequencing. J Clin Microbiol 2014 Liu C;Lin J;Chen H;Shang H;Jiang L;Chen J;Ye Y;Yang B;Ou Q View More
25078390 Antiviral activity of baicalin against influenza A (H1N1/H3N2) virus in cell culture and in mice and its inhibition of neuraminidase. Arch Virol 2014 Ding Y;Dou J;Teng Z;Yu J;Wang T;Lu N;Wang H;Zhou C View More
2547069 Synthesis and antirhinovirus activity of 6-(dimethylamino)-2-(trifluoromethyl)-9-(substituted benzyl)-9H-purines. J Med Chem 1989 Kelley JL;Linn JA;Selway JW View More
2558631 Drug resistant rhinoviruses from the nose of experimentally treated volunteers. Arch Virol 1989 Dearden C;al-Nakib W;Andries K;Woestenborghs R;Tyrrell DA View More
26071135 Exploration of the anti-enterovirus activity of a series of pleconaril/pirodavir-like compounds. Antivir Chem Chemother 2015 Bernard A;Lacroix C;Cabiddu MG;Neyts J;Leyssen P;Pompei R View More
26149998 In Vitro Efficacy of Antiviral Compounds against Enterovirus D68. Antimicrob Agents Chemother 2015 Rhoden E;Zhang M;Nix WA;Oberste MS View More
26169596 In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses. Virol J 2015 Lacroix C;Laconi S;Angius F;Coluccia A;Silvestri R;Pompei R;Neyts J;Leyssen P View More
26372075 Synthesis and antiviral activity of maleopimaric and quinopimaric acids\' derivatives. Bioorg Med Chem 2015 Tretyakova EV;Smirnova IE;Salimova EV;Odinokov VN View More
26391975 Molecular mechanism of a specific capsid binder resistance caused by mutations outside the binding pocket. Antiviral Res 2015 Braun H;Kirchmair J;Williamson MJ;Makarov VA;Riabova OB;Glen RC;Sauerbrei A;Schmidtke M View More
27090557 Purine analogs as phosphatidylinositol 4-kinase IIIbeta inhibitors. Bioorg Med Chem Lett 2016 Sala M;Kogler M;Plackova P;Mejdrova I;Hrebabecky H;Prochazkova E;Strunin D;Lee G;Birkus G;Weber J;Mertlikova-Kaiserova H;Nencka R View More
27265257 Design and structure-activity relationships of novel inhibitors of human rhinovirus 3C protease. Bioorg Med Chem Lett 2016 Kawatkar SP;Gagnon M;Hoesch V;Tiong-Yip C;Johnson K;Ek M;Nilsson E;Lister T;Olsson L;Patel J;Yu Q View More
27412593 Poliovirus Polymerase Leu420 Facilitates RNA Recombination and Ribavirin Resistance. J Virol 2016 Kempf BJ;Peersen OB;Barton DJ View More
27542891 Antiviral activity of aspirin against RNA viruses of the respiratory tract-an in vitro study. Influenza Other Respir Viruses 2017 Glatthaar-Saalmuller B;Mair KH;Saalmuller A View More
27905101 A review on antiviral activity of the Himalayan medicinal plants traditionally used to treat bronchitis and related symptoms. J Pharm Pharmacol 2017 Amber R;Adnan M;Tariq A;Mussarat S View More
28118832 In vitro screening for antiviral activity of Turkish plants revealing methanolic extract of Rindera lanata var. lanata active against human rotavirus. BMC Complement Altern Med 2017 Civra A;Francese R;Sinato D;Donalisio M;Cagno V;Rubiolo P;Ceylan R;Uysal A;Zengin G;Lembo D View More
28242170 3-Phenylalkyl-2H-chromenes and -chromans as novel rhinovirus infection inhibitors. Bioorg Med Chem 2017 Conti C;Proietti Monaco L;Desideri N View More
2835768 Structural analysis of a series of antiviral agents complexed with human rhinovirus 14. Proc Natl Acad Sci U S A 1988 Badger J;Minor I;Kremer MJ;Oliveira MA;Smith TJ;Griffith JP;Guerin DM;Krishnaswamy S;Luo M;Rossmann MG;et al. View More
2845889 In vitro activity of R 61837, a new antirhinovirus compound. Arch Virol 1988 Andries K;Dewindt B;De Brabander M;Stokbroekx R;Janssen PA View More
28581749 A Novel Series of Highly Potent Small Molecule Inhibitors of Rhinovirus Replication. J Med Chem 2017 Kim J;Jung YK;Kim C;Shin JS;Scheers E;Lee JY;Han SB;Lee CK;Neyts J;Ha JD;Jung YS View More
28914420 Labdane-type diterpenoids from Vitex limonifolia and their antivirus activities. J Nat Med 2018 Ban NK;Thoa NTK;Linh TM;Trang DT;Van Kiem P;Nhiem NX;Tai BH;Van Minh C;Song JH;Ko HJ;Kim SH View More
29433930 Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2018 Namoto K;Sirockin F;Sellner H;Wiesmann C;Villard F;Moreau RJ;Valeur E;Paulding SC;Schleeger S;Schipp K;Loup J;Andrews L;Swale R;Robinson M;Farady CJ View More
29562753 Nucleosides for the treatment of respiratory RNA virus infections. Antivir Chem Chemother 2018 Jordan PC;Stevens SK;Deval J View More
29866517 Identification of quinone analogues as potential inhibitors of picornavirus 3C protease in vitro. Bioorg Med Chem Lett 2018 Jung E;Lee JY;Kim HJ;Ryu CK;Lee KI;Kim M;Lee CK;Go YY View More
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3027340 Structure-activity studies of 5-[[4-(4,5-dihydro-2-oxazolyl) phenoxy]alkyl]-3-methylisoxazoles: inhibitors of picornavirus uncoating. J Med Chem 1987 Diana GD;Oglesby RC;Akullian V;Carabateas PM;Cutcliffe D;Mallamo JP;Otto MJ;McKinlay MA;Maliski EG;Michalec SJ View More
31203807 Thiazole Compounds as Antiviral Agents: An Update. Med Chem 2020 Singh IP;Gupta S;Kumar S View More
31226653 Back to the future: Advances in development of broad-spectrum capsid-binding inhibitors of enteroviruses. Eur J Med Chem 2019 Egorova A;Ekins S;Schmidtke M;Makarov V View More
31881489 Novel pleconaril derivatives: Influence of substituents in the isoxazole and phenyl rings on the antiviral activity against enteroviruses. Eur J Med Chem 2020 Egorova A;Kazakova E;Jahn B;Ekins S;Makarov V;Schmidtke M View More
32358920 Epidemiology of bacteria and viruses in the respiratory tract of humans and domestic pigs. APMIS 2020 Bunke J;Receveur K;Oeser AC;Gutsmann I;Schubert S;Podschun R;Zell R;Fickenscher H;Krumbholz A View More
32716466 A light- and heat-driven glycal diazidation approach to nitrogenous carbohydrate derivatives with antiviral activity. Org Biomol Chem 2020 He H;Cao R;Cao R;Liu XY;Li W;Yu D;Li Y;Liu M;Wu Y;Wu P;Yang JS;Yan Y;Yang J;Zheng ZB;Zhong W;Qin Y View More
32845461 Caspofungin Effects on Electrocardiogram of Mice: An Evaluation of Cardiac Safety. Cardiovasc Toxicol 2021 De Paula DCC;Leite EA;Araujo CM;Branquinho RT;Guimaraes HN;Grabe-Guimaraes A View More
33357221 Comparative in vitro analysis of inhibition of rhinovirus and influenza virus replication by mucoactive secretolytic agents and plant extracts. BMC Complement Med Ther 2020 Walther C;Doring K;Schmidtke M View More
33546185 Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus. Viruses 2021 Al-Beltagi S;Preda CA;Goulding LV;James J;Pu J;Skinner P;Jiang Z;Wang BL;Yang J;Banyard AC;Mellits KH;Gershkovich P;Hayes CJ;Nguyen-Van-Tam J;Brown IH;Liu J;Chang KC View More
33872498 Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2. J Med Chem 2022 Dai W;Jochmans D;Xie H;Yang H;Li J;Su H;Chang D;Wang J;Peng J;Zhu L;Nian Y;Hilgenfeld R;Jiang H;Chen K;Zhang L;Xu Y;Neyts J;Liu H View More
34285133 Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2. Science 2021 Drayman N;DeMarco JK;Jones KA;Azizi SA;Froggatt HM;Tan K;Maltseva NI;Chen S;Nicolaescu V;Dvorkin S;Furlong K;Kathayat RS;Firpo MR;Mastrodomenico V;Bruce EA;Schmidt MM;Jedrzejczak R;Munoz-Alia MA;Schuster B;Nair V;Han KY;O'Brien A;Tomatsidou A;Meyer B;Vignuzzi M;Missiakas D;Botten JW;Brooke CB;Lee H;Baker SC;Mounce BC;Heaton NS;Severson WE;Palmer KE;Dickinson BC;Joachimiak A;Randall G;Tay S View More
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