| Title | [In vitro experimental study on the effect of resveratrol against several kinds of respiroviruses]. | ||
| Author | Guan, Wen-Da; Yang, Zi-Feng; Liu, Ni; Qin, Sheng; Zhang, Feng-Xue; Zhu, Yu-Tong | ||
| Journal | Zhong Yao Cai | Publication Year/Month | 2008-Sep |
| PMID | 19180966 | PMCID | -N/A- |
| Affiliation | 1.Molecular Immunology and Antibody Engineering Center, Jinan University, Guangzhou 510632, China. | ||
OBJECTIVE: To observe the cytopathogenic inhibitory effect of resveratrol on vary respiroviruses and explore the mechanism of resveratrol against viruses. METHODS: MDCK, A549, HEp-2 cell and MRC-5 were infected with Influenza virus type A FM1 strain, rhinovirus type R14, RS virus, AD virus type 7 separately, and the antiviral activity of resveratrol were observed. RESULTS: Resveratrol significantly inhibited cytopathogenic effect of AD virus type 7 at the concentration 120 microg/ml. No significant cytopathogenic effect of Resveratrol inhibiting Influenza virus type A FM1 strain, Rhinovirus type R14, RS virus on separate cells was observed. CONCLUSION: It is concluded that resveratrol is effective on inhibiting AD virus type 7 in vitro, however, its mechanism is needed for further study.