| Title | Spectrum of activity of soluble intercellular adhesion molecule-1 against rhinovirus reference strains and field isolates. | ||
| Author | Ohlin, A; Hoover-Litty, H; Sanderson, G; Paessens, A; Johnston, S L; Holgate, S T; Huguenel, E; Greve, J M | ||
| Journal | Antimicrob Agents Chemother | Publication Year/Month | 1994-Jun |
| PMID | 7916557 | PMCID | PMC188221 |
| Affiliation | 1.Institute for Inflammation and Experimental Medicine, Miles Biotechnology, West Haven, Connecticut 06516. | ||
The antiviral potency of soluble intercellular adhesion molecule-1 (ICAM-1; the major receptor for human rhinoviruses) was determined for a subset of American Type Culture Collection reference serotypes and field isolates of rhinovirus. The results indicate that soluble ICAM-1 exhibits a broad spectrum of activity against rhinoviruses and that field isolates have a sensitivity indistinguishable from that of laboratory strains.