PMID Title Journal Publication Year Author View in RVdb
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16906156 Role of deficient type III interferon-lambda production in asthma exacerbations. Nat Med 2006 Contoli M;Message SD;Laza-Stanca V;Edwards MR;Wark PA;Bartlett NW;Kebadze T;Mallia P;Stanciu LA;Parker HL;Slater L;Lewis-Antes A;Kon OM;Holgate ST;Davies DE;Kotenko SV;Papi A;Johnston SL View More
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17607011 Innate immunity in the pathogenesis of virus-induced asthma exacerbations. Proc Am Thorac Soc 2007 Johnston SL View More
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17959848 Upregulation of interferon-induced genes in infants with virus-associated acute bronchiolitis. Exp Biol Med (Maywood) 2007 Scagnolari C;Midulla F;Trombetti S;Pierangeli A;Tromba V;Grossi R;Di Marco P;Dianzani C;Girardi E;Antonelli G View More
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18564328 Type III IFN-lambda mRNA expression in sputum of adult and school-aged asthmatics. Clin Exp Allergy 2008 Bullens DM;Decraene A;Dilissen E;Meyts I;De Boeck K;Dupont LJ;Ceuppens JL View More
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19175599 Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells. Allergy 2009 Khaitov MR;Laza-Stanca V;Edwards MR;Walton RP;Rohde G;Contoli M;Papi A;Stanciu LA;Kotenko SV;Johnston SL View More
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19875225 The connection between early life wheezing and subsequent asthma: The viral march. Allergol Immunopathol (Madr) 2009 Martinez FD View More
20051716 Human rhinoviruses, allergy, and asthma: a clinical approach. Medicina (Kaunas) 2009 Emuzyte R;Firantiene R;Petraityte R;Sasnauskas K View More
20150207 Azithromycin induces anti-viral responses in bronchial epithelial cells. Eur Respir J 2010 Gielen V;Johnston SL;Edwards MR View More
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21637773 MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness. PLoS Pathog 2011 Wang Q;Miller DJ;Bowman ER;Nagarkar DR;Schneider D;Zhao Y;Linn MJ;Goldsmith AM;Bentley JK;Sajjan US;Hershenson MB View More
21825067 Pseudomonas aeruginosa suppresses interferon response to rhinovirus infection in cystic fibrosis but not in normal bronchial epithelial cells. Infect Immun 2011 Chattoraj SS;Ganesan S;Faris A;Comstock A;Lee WM;Sajjan US View More
21917654 Impaired type I and III interferon response to rhinovirus infection during pregnancy and asthma. Thorax 2012 Forbes RL;Gibson PG;Murphy VE;Wark PA View More
21984364 Asthma and pregnancy: do they give clues to abnormal antiviral activity? Thorax 2012 Busse WW;Gern JE View More
22054758 Interferons as therapeutic agents for infectious diseases. Infect Dis Clin North Am 2011 Bergman SJ;Ferguson MC;Santanello C View More
22058416 Regulation of IFN-lambda1 promoter activity (IFN-lambda1/IL-29) in human airway epithelial cells. J Immunol 2011 Siegel R;Eskdale J;Gallagher G View More
22135341 A mechanistic role for type III IFN-lambda1 in asthma exacerbations mediated by human rhinoviruses. Am J Respir Crit Care Med 2012 Miller EK;Hernandez JZ;Wimmenauer V;Shepherd BE;Hijano D;Libster R;Serra ME;Bhat N;Batalle JP;Mohamed Y;Reynaldi A;Rodriguez A;Otello M;Pisapia N;Bugna J;Bellabarba M;Kraft D;Coviello S;Ferolla FM;Chen A;London SJ;Siberry GK;Williams JV;Polack FP View More
22205631 Negative control of TLR3 signaling by TICAM1 down-regulation. Am J Respir Cell Mol Biol 2012 Tao S;Zhu L;Lee P;Lee WM;Knox K;Chen J;Di YP;Chen Y View More
22213737 Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells. Thorax 2012 Vareille M;Kieninger E;Alves MP;Kopf BS;Moller A;Geiser T;Johnston SL;Edwards MR;Regamey N View More
22355409 Lower respiratory tract infection induced by a genetically modified picornavirus in its natural murine host. PLoS One 2012 Rosenthal LA;Szakaly RJ;Amineva SP;Xing Y;Hill MR;Palmenberg AC;Gern JE;Sorkness RL View More
22383563 Interferon-lambda1 and viral wheeze in asthma: a Gothic duality? Am J Respir Crit Care Med 2012 Gern JE View More
22465313 Quercetin inhibits rhinovirus replication in vitro and in vivo. Antiviral Res 2012 Ganesan S;Faris AN;Comstock AT;Wang Q;Nanua S;Hershenson MB;Sajjan US View More
22766097 Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children. J Allergy Clin Immunol 2012 Durrani SR;Montville DJ;Pratt AS;Sahu S;DeVries MK;Rajamanickam V;Gangnon RE;Gill MA;Gern JE;Lemanske RF Jr;Jackson DJ View More
22808255 Cigarette smoke modulates expression of human rhinovirus-induced airway epithelial host defense genes. PLoS One 2012 Proud D;Hudy MH;Wiehler S;Zaheer RS;Amin MA;Pelikan JB;Tacon CE;Tonsaker TO;Walker BL;Kooi C;Traves SL;Leigh R View More
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22981791 Deficient antiviral immune responses in childhood: distinct roles of atopy and asthma. J Allergy Clin Immunol 2012 Baraldo S;Contoli M;Bazzan E;Turato G;Padovani A;Marku B;Calabrese F;Caramori G;Ballarin A;Snijders D;Barbato A;Saetta M;Papi A View More
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23212197 Impaired innate interferon induction in severe therapy resistant atopic asthmatic children. Mucosal Immunol 2013 Edwards MR;Regamey N;Vareille M;Kieninger E;Gupta A;Shoemark A;Saglani S;Sykes A;Macintyre J;Davies J;Bossley C;Bush A;Johnston SL View More
23658644 Rhinovirus and dsRNA induce RIG-I-like receptors and expression of interferon beta and lambda1 in human bronchial smooth muscle cells. PLoS One 2013 Calven J;Yudina Y;Uller L View More
23806456 Interaction between allergy and innate immunity: model for eosinophil regulation of epithelial cell interferon expression. Ann Allergy Asthma Immunol 2013 Mathur SK;Fichtinger PS;Kelly JT;Lee WM;Gern JE;Jarjour NN View More
23824215 TLR3, TLR4 and TLRs7-9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma. PLoS One 2013 Sykes A;Edwards MR;Macintyre J;Del Rosario A;Gielen V;Haas J;Kon OM;McHale M;Johnston SL View More
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24131248 TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection. Clin Exp Allergy 2014 Parsons KS;Hsu AC;Wark PA View More
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2447197 Role of interferon in leukocyte histamine release caused by common respiratory viruses. J Infect Dis 1988 Chonmaitree T;Lett-Brown MA;Tsong Y;Goldman AS;Baron S View More
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2461669 Experimental rhinovirus infection in human volunteers exposed to ozone. Am Rev Respir Dis 1988 Henderson FW;Dubovi EJ;Harder S;Seal E Jr;Graham D View More
24751942 Efficacy of IFN-lambda1 to protect human airway epithelial cells against human rhinovirus 1B infection. PLoS One 2014 Gulraiz F;Bellinghausen C;Dentener MA;Reynaert NL;Gaajetaan GR;Beuken EV;Rohde GG;Bruggeman CA;Stassen FR View More
24753610 Interferon induction of IFITM proteins promotes infection by human coronavirus OC43. Proc Natl Acad Sci U S A 2014 Zhao X;Guo F;Liu F;Cuconati A;Chang J;Block TM;Guo JT View More
24811725 Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy. Thorax 2014 Spann KM;Baturcam E;Schagen J;Jones C;Straub CP;Preston FM;Chen L;Phipps S;Sly PD;Fantino E View More
25216987 Interferon response and respiratory virus control are preserved in bronchial epithelial cells in asthma. J Allergy Clin Immunol 2014 Patel DA;You Y;Huang G;Byers DE;Kim HJ;Agapov E;Moore ML;Peebles RS Jr;Castro M;Sumino K;Shifren A;Brody SL;Holtzman MJ View More
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25359346 Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells. Eur Respir J 2015 Schogler A;Kopf BS;Edwards MR;Johnston SL;Casaulta C;Kieninger E;Jung A;Moeller A;Geiser T;Regamey N;Alves MP View More
25417801 Glucocorticosteroids enhance replication of respiratory viruses: effect of adjuvant interferon. Sci Rep 2014 Thomas BJ;Porritt RA;Hertzog PJ;Bardin PG;Tate MD View More
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25784275 Severity of virus-induced asthma symptoms is inversely related to resolution IFN-lambda expression. J Allergy Clin Immunol 2015 Schwantes EA;Denlinger LC;Evans MD;Gern JE;Jarjour NN;Mathur SK View More
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25847975 CCL7 and IRF-7 Mediate Hallmark Inflammatory and IFN Responses following Rhinovirus 1B Infection. J Immunol 2015 Girkin J;Hatchwell L;Foster P;Johnston SL;Bartlett N;Collison A;Mattes J View More
25879848 Trehalose-mediated autophagy impairs the anti-viral function of human primary airway epithelial cells. PLoS One 2015 Wu Q;Jiang D;Huang C;van Dyk LF;Li L;Chu HW View More
26108570 Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia. Thorax 2015 Hatchwell L;Collison A;Girkin J;Parsons K;Li J;Zhang J;Phipps S;Knight D;Bartlett NW;Johnston SL;Foster PS;Wark PA;Mattes J View More
26376925 Understanding the Association of Human Rhinovirus with Asthma. Clin Vaccine Immunol 2016 Stone CA Jr;Miller EK View More
26613982 Interferon response of the cystic fibrosis bronchial epithelium to major and minor group rhinovirus infection. J Cyst Fibros 2016 Schogler A;Stokes AB;Casaulta C;Regamey N;Edwards MR;Johnston SL;Jung A;Moeller A;Geiser T;Alves MP View More
26836624 Rhinovirus-induced asthma exacerbations and risk populations. Curr Opin Allergy Clin Immunol 2016 Coleman L;Laing IA;Bosco A View More
27003171 Gene Knockdown in Human Rhinovirus 1B Using 2\'-OMe-modified siRNAs Results in the Reactivation of the Interferon Response. Biomed Environ Sci 2016 Xie GC;Zhang Q;Pang LL;Li DD;Jin M;Li HY;Xu ZQ;Kong XY;Wang H;Lu S;Duan ZJ View More
27402752 Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature. Proc Natl Acad Sci U S A 2016 Foxman EF;Storer JA;Vanaja K;Levchenko A;Iwasaki A View More
27494903 Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium. J Antimicrob Chemother 2016 Porter JD;Watson J;Roberts LR;Gill SK;Groves H;Dhariwal J;Almond MH;Wong E;Walton RP;Jones LH;Tregoning J;Kilty I;Johnston SL;Edwards MR View More
27667736 Impaired virus replication and decreased innate immune responses to viral infections in nasal epithelial cells from patients with allergic rhinitis. Clin Exp Immunol 2017 Globinska A;Pawelczyk M;Piechota-Polanczyk A;Olszewska-Ziaber A;Moskwa S;Mikolajczyk A;Jablonska A;Zakrzewski PK;Brauncajs M;Jarzebska M;Taka S;Papadopoulos NG;Kowalski ML View More
27836955 IFN-alpha/IFN-lambda responses to respiratory viruses in paediatric asthma. Eur Respir J 2017 Bergauer A;Sopel N;Kross B;Vuorinen T;Xepapadaki P;Weiss ST;Blau A;Sharma H;Kraus C;Springel R;Rauh M;Mittler S;Graser A;Zimmermann T;Melichar VO;Kiefer A;Kowalski ML;Sobanska A;Jartti T;Lukkarinen H;Papadopoulos NG;Finotto S View More
27838350 Vitamin D increases the antiviral activity of bronchial epithelial cells in vitro. Antiviral Res 2017 Telcian AG;Zdrenghea MT;Edwards MR;Laza-Stanca V;Mallia P;Johnston SL;Stanciu LA View More
28069942 A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection. Proc Natl Acad Sci U S A 2017 Saxena K;Simon LM;Zeng XL;Blutt SE;Crawford SE;Sastri NP;Karandikar UC;Ajami NJ;Zachos NC;Kovbasnjuk O;Donowitz M;Conner ME;Shaw CA;Estes MK View More
28077283 Aetiology of febrile pharyngitis in children: Potential of myxovirus resistance protein A (MxA) as a biomarker of viral infection. J Infect 2017 Ivaska L;Niemela J;Lempainen J;Osterback R;Waris M;Vuorinen T;Hytonen J;Rantakokko-Jalava K;Peltola V View More
28356234 Efficacy of novel antibody-based drugs against rhinovirus infection: In vitro and in vivo results. Antiviral Res 2017 Petrova NV;Emelyanova AG;Gorbunov EA;Edwards MR;Walton RP;Bartlett NW;Aniscenko J;Gogsadze L;Bakhsoliani E;Khaitov MR;Johnston SL;Tarasov SA;Epstein OI View More
28356379 Rhinovirus species/genotypes and interferon-lambda: subtypes, receptor and polymorphisms - missing pieces of the puzzle of childhood asthma? Eur Respir J 2017 Scagnolari C;Midulla F;Nenna R;Papoff P;Antonelli G;Pierangeli A View More
28356381 Rhinovirus species/genotypes and interferon-lambda: subtypes, receptor and polymorphisms - missing pieces of the puzzle of childhood asthma? Eur Respir J 2017 Bergauer A;Sopel N;Kross B;Vuorinen T;Xepapadaki P;Weiss ST;Blau A;Sharma H;Kraus C;Springel R;Rauh M;Mittler S;Graser A;Zimmermann T;Melichar VO;Kiefer A;Kowalski ML;Sobanska A;Jartti T;Lukkarinen H;Papadopoulos NG;Finotto S View More
28555543 Broad-spectrum inhibition of common respiratory RNA viruses by a pyrimidine synthesis inhibitor with involvement of the host antiviral response. J Gen Virol 2017 Cheung NN;Lai KK;Dai J;Kok KH;Chen H;Chan KH;Yuen KY;Kao RYT View More
28581456 Epigenetic silencing of IRF1 dysregulates type III interferon responses to respiratory virus infection in epithelial to mesenchymal transition. Nat Microbiol 2017 Yang J;Tian B;Sun H;Garofalo RP;Brasier AR View More
28606988 Recurrent rhinovirus infections in a child with inherited MDA5 deficiency. J Exp Med 2017 Lamborn IT;Jing H;Zhang Y;Drutman SB;Abbott JK;Munir S;Bade S;Murdock HM;Santos CP;Brock LG;Masutani E;Fordjour EY;McElwee JJ;Hughes JD;Nichols DP;Belkadi A;Oler AJ;Happel CS;Matthews HF;Abel L;Collins PL;Subbarao K;Gelfand EW;Ciancanelli MJ;Casanova JL;Su HC View More
28827284 Rhinovirus Infection of ORMDL3 Transgenic Mice Is Associated with Reduced Rhinovirus Viral Load and Airway Inflammation. J Immunol 2017 Song DJ;Miller M;Beppu A;Rosenthal P;Das S;Karta M;Vuong C;Mehta AK;Croft M;Broide DH View More
28931654 Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs. Sci Transl Med 2017 Brown MC;Holl EK;Boczkowski D;Dobrikova E;Mosaheb M;Chandramohan V;Bigner DD;Gromeier M;Nair SK View More
29228279 In Vitro Model of Fully Differentiated Human Nasal Epithelial Cells Infected With Rhinovirus Reveals Epithelium-Initiated Immune Responses. J Infect Dis 2018 Tan KS;Ong HH;Yan Y;Liu J;Li C;Ong YK;Thong KT;Choi HW;Wang DY;Chow VT View More
29319193 House dust mite impairs antiviral response in asthma exacerbation models through its effects on TLR3. Allergy 2018 Akbarshahi H;Menzel M;Ramu S;Mahmutovic Persson I;Bjermer L;Uller L View More
29425849 Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses. J Allergy Clin Immunol 2018 van der Vlugt LEPM;Eger K;Muller C;Ninaber DK;Zarcone MC;Amatngalim GD;Bracher F;von Mutius E;Smits HH;Hiemstra PS View More
30512082 Airway Cells Make Trade-off When Fighting the Cold Virus. JAMA 2018 Hampton T View More
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31430424 Are rhinoviruses implicated in the pathogenesis of sinusitis and chronic rhinosinusitis exacerbations? A comprehensive review. Int Forum Allergy Rhinol 2019 Basharat U;Aiche MM;Kim MM;Sohal M;Chang EH View More
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31548332 Rhinovirus-Induced SIRT-1 via TLR2 Regulates Subsequent Type I and Type III IFN Responses in Airway Epithelial Cells. J Immunol 2019 Xander N;Reddy Vari H;Eskandar R;Li W;Bolla S;Marchetti N;Sajjan US View More
31557636 Increased type 2 inflammation post rhinovirus infection in patients with moderate asthma. Cytokine 2020 Southworth T;Pattwell C;Khan N;Mowbray SF;Strieter RM;Erpenbeck VJ;Singh D View More
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31849956 Oxidative Stress Attenuates TLR3 Responsiveness and Impairs Anti-viral Mechanisms in Bronchial Epithelial Cells From COPD and Asthma Patients. Front Immunol 2019 Menzel M;Ramu S;Calven J;Olejnicka B;Sverrild A;Porsbjerg C;Tufvesson E;Bjermer L;Akbarshahi H;Uller L View More
31874655 [Expression of interferon-lambda1 in respiratory epithelial cells in children with human rhinovirus infection]. Zhongguo Dang Dai Er Ke Za Zhi 2019 Lin XJ;Zhong LL;Xie YP;Deng ZP View More
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32581261 Interferon-Dependent and Respiratory Virus-Specific Interference in Dual Infections of Airway Epithelia. Sci Rep 2020 Essaidi-Laziosi M;Geiser J;Huang S;Constant S;Kaiser L;Tapparel C View More
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33303556 TLR7/8 regulates type I and type III interferon signalling in rhinovirus 1b-induced allergic asthma. Eur Respir J 2021 Krug J;Kiefer A;Koelle J;Vuorinen T;Xepapadaki P;Stanic B;Chiriac MT;Akdis M;Zimmermann T;Papadopoulos NG;Finotto S View More
33432184 A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection. Nat Genet 2021 Blume C;Jackson CL;Spalluto CM;Legebeke J;Nazlamova L;Conforti F;Perotin JM;Frank M;Butler J;Crispin M;Coles J;Thompson J;Ridley RA;Dean LSN;Loxham M;Reikine S;Azim A;Tariq K;Johnston DA;Skipp PJ;Djukanovic R;Baralle D;McCormick CJ;Davies DE;Lucas JS;Wheway G;Mennella V View More
33590936 Genetic and epigenetic factors associated with increased severity of Covid-19. Cell Biol Int 2021 Yildirim Z;Sahin OS;Yazar S;Bozok Cetintas V View More
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