Title | The role of interferon in virus infections and antibody formation. | ||
Author | Stanton, G J; Johnson, H M; Baron, S | ||
Journal | Pathobiol Annu | Publication Year/Month | 1978 |
PMID | 214736 | PMCID | -N/A- |
Virus-type interferon is capable of suppressing the antibody response both in vivo and in vitro. Interferon induced by antigen or mitogen (immune interferon), primarily in T-lymphocytes, also appears capable of suppressing the antibody response. Cyclic AMP has a regulatory effect on the induction of both virus-type and immune interferon. The immunosuppressive effects of virus-type and immune interferon may differ at the cellular or subcellular level.