PMID Title Journal Publication Year Author View in RVdb
10794684 Substituted benzamide inhibitors of human rhinovirus 3C protease: structure-based design, synthesis, and biological evaluation. J Med Chem 2000 Reich SH;Johnson T;Wallace MB;Kephart SE;Fuhrman SA;Worland ST;Matthews DA;Hendrickson TF;Chan F;Meador J 3rd;Ferre RA;Brown EL;DeLisle DM;Patick AK;Binford SL;Ford CE View More
11591501 Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2001 Webber SE;Marakovits JT;Dragovich PS;Prins TJ;Zhou R;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Srinivasan B;Moran T;Ford CE;Brothers MA;Harr JE;Meador JW 3rd;Ferre RA;Worland ST View More
13678411 Imidazo[1,2-b]pyridazines, novel nucleus with potent and broad spectrum activity against human picornaviruses: design, synthesis, and biological evaluation. J Med Chem 2003 Hamdouchi C;Sanchez-Martinez C;Gruber J;Del Prado M;Lopez J;Rubio A;Heinz BA View More
16130524 Synthesis and anti-rhinovirus properties of fluoro-substituted flavonoids. Antivir Chem Chemother 2005 Conti C;Mastromarino P;Goldoni P;Portalone G;Desideri N View More
17305557 Human rhinovirus 3C protease as a potential target for the development of antiviral agents. Curr Protein Pept Sci 2007 Wanga QM;Chen SH View More
18046960 Isothiazole derivatives as antiviral agents. Antivir Chem Chemother 2007 Garozzo A;Cutri CC;Pannecouque C;Castro A;Guerrera F;De Clercq E View More
18840470 New pleconaril and [(biphenyloxy)propyl]isoxazole derivatives with substitutions in the central ring exhibit antiviral activity against pleconaril-resistant coxsackievirus B3. Antiviral Res 2009 Schmidtke M;Wutzler P;Zieger R;Riabova OB;Makarov VA View More
19464175 Structure-activity relationships of heteroaromatic esters as human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2009 Im I;Lee ES;Choi SJ;Lee JY;Kim YC View More
21930871 Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus. Antimicrob Agents Chemother 2012 Hsu JT;Yeh JY;Lin TJ;Li ML;Wu MS;Hsieh CF;Chou YC;Tang WF;Lau KS;Hung HC;Fang MY;Ko S;Hsieh HP;Horng JT View More
22088306 Design, synthesis and in vitro evaluation of novel chroman-4-one, chroman, and 2H-chromene derivatives as human rhinovirus capsid-binding inhibitors. Bioorg Med Chem 2011 Conti C;Proietti Monaco L;Desideri N View More
22202806 Synthesis of 1,4-disubstituted mono and bis-triazolocarbo-acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine by Cu(I)-catalyzed click azide-alkyne cycloaddition. Molecules 2011 Krim J;Taourirte M;Engels JW View More
23726345 Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus. Bioorg Med Chem Lett 2013 Decor A;Grand-Maitre C;Hucke O;O'Meara J;Kuhn C;Constantineau-Forget L;Brochu C;Malenfant E;Bertrand-Laperle M;Bordeleau J;Ghiro E;Pesant M;Fazal G;Gorys V;Little M;Boucher C;Bordeleau S;Turcotte P;Guo T;Garneau M;Spickler C;Gauthier A View More
24360829 Synthesis and anti-rhinovirus activity of novel 3-[2-(pyridinyl)vinyl]substituted -2H-chromenes and -4H-chromen-4-ones. Bioorg Med Chem 2014 Conti C;Proietti Monaco L;Desideri N View More
24973816 Synthesis of new compounds with promising antiviral properties against group A and B Human Rhinoviruses. Bioorg Med Chem 2014 Bernard AM;Cabiddu MG;De Montis S;Mura R;Pompei R View More
26055709 The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. J Biol Chem 2015 Wood ER;Bledsoe R;Chai J;Daka P;Deng H;Ding Y;Harris-Gurley S;Kryn LH;Nartey E;Nichols J;Nolte RT;Prabhu N;Rise C;Sheahan T;Shotwell JB;Smith D;Tai V;Taylor JD;Tomberlin G;Wang L;Wisely B;You S;Xia B;Dickson H View More
26071135 Exploration of the anti-enterovirus activity of a series of pleconaril/pirodavir-like compounds. Antivir Chem Chemother 2015 Bernard A;Lacroix C;Cabiddu MG;Neyts J;Leyssen P;Pompei R View More
26659560 Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Syncytial Virus and Other Respiratory Viruses. PLoS One 2015 Ohol YM;Wang Z;Kemble G;Duke G View More
27090557 Purine analogs as phosphatidylinositol 4-kinase IIIbeta inhibitors. Bioorg Med Chem Lett 2016 Sala M;Kogler M;Plackova P;Mejdrova I;Hrebabecky H;Prochazkova E;Strunin D;Lee G;Birkus G;Weber J;Mertlikova-Kaiserova H;Nencka R View More
27265257 Design and structure-activity relationships of novel inhibitors of human rhinovirus 3C protease. Bioorg Med Chem Lett 2016 Kawatkar SP;Gagnon M;Hoesch V;Tiong-Yip C;Johnson K;Ek M;Nilsson E;Lister T;Olsson L;Patel J;Yu Q View More
28581749 A Novel Series of Highly Potent Small Molecule Inhibitors of Rhinovirus Replication. J Med Chem 2017 Kim J;Jung YK;Kim C;Shin JS;Scheers E;Lee JY;Han SB;Lee CK;Neyts J;Ha JD;Jung YS View More
29433930 Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2018 Namoto K;Sirockin F;Sellner H;Wiesmann C;Villard F;Moreau RJ;Valeur E;Paulding SC;Schleeger S;Schipp K;Loup J;Andrews L;Swale R;Robinson M;Farady CJ View More
29866517 Identification of quinone analogues as potential inhibitors of picornavirus 3C protease in vitro. Bioorg Med Chem Lett 2018 Jung E;Lee JY;Kim HJ;Ryu CK;Lee KI;Kim M;Lee CK;Go YY View More
2989517 Isoxazoles with antipicornavirus activity. J Med Chem 1985 Diana GD;McKinlay MA;Brisson CJ;Zalay ES;Miralles JV;Salvador UJ View More
30844608 New 4-phenylcoumarin derivatives as potent 3C protease inhibitors: Design, synthesis, anti-HAV effect and molecular modeling. Eur J Med Chem 2019 Kassem AF;Batran RZ;Abbas EMH;Elseginy SA;Shaheen MNF;Elmahdy EM View More
32234539 Synthesis and antiviral effect of novel fluoxetine analogues as enterovirus 2C inhibitors. Antiviral Res 2020 Manganaro R;Zonsics B;Bauer L;Lorenzo Lopez M;Donselaar T;Zwaagstra M;Saporito F;Ferla S;Strating JRPM;Coutard B;Hurdiss DL;van Kuppeveld FJM;Brancale A View More
32716466 A light- and heat-driven glycal diazidation approach to nitrogenous carbohydrate derivatives with antiviral activity. Org Biomol Chem 2020 He H;Cao R;Cao R;Liu XY;Li W;Yu D;Li Y;Liu M;Wu Y;Wu P;Yang JS;Yan Y;Yang J;Zheng ZB;Zhong W;Qin Y View More
32949635 A synthetic STING agonist inhibits the replication of human parainfluenza virus 3 and rhinovirus 16 through distinct mechanisms. Antiviral Res 2020 Zhu Q;Hu H;Liu H;Shen H;Yan Z;Gao L View More
33872498 Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2. J Med Chem 2022 Dai W;Jochmans D;Xie H;Yang H;Li J;Su H;Chang D;Wang J;Peng J;Zhu L;Nian Y;Hilgenfeld R;Jiang H;Chen K;Zhang L;Xu Y;Neyts J;Liu H View More
4339771 Azapurine nucleosides. 3. Synthesis of 7-( -D-ribofuranosyl)imidazo(4,5-d)-v-triazin-4-one(2-azainosine) and related derivatives. J Med Chem 1972 Kawana M;Ivanovics GA;Rousseau RJ;Robins RK View More
4365201 Potential antidiabetics. 9. Biological activity of some pyrazoles. J Med Chem 1971 Garg HG;Prakash C View More
4370230 Nucleoside peptides. 6. Synthesis of certain N-(5-amino-1-(beta-D-ribofuranosyl)imidazole-4-carbonyl)amino acids related to naturally occurring intermediates in the purine biosynthetic pathway. J Med Chem 1974 Srivastava PC;Mancuso RW;Rousseau RJ;Robins RK View More
8648640 Synthesis and activity of piperazine-containing antirhinoviral agents and crystal structure of SDZ 880-061 bound to human rhinovirus 14. J Mol Biol 1996 Oren DA;Zhang A;Nesvadba H;Rosenwirth B;Arnold E View More
8978838 Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease. J Med Chem 1996 Webber SE;Tikhe J;Worland ST;Fuhrman SA;Hendrickson TF;Matthews DA;Love RA;Patick AK;Meador JW;Ferre RA;Brown EL;DeLisle DM;Ford CE;Binford SL View More
9667969 Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements. J Med Chem 1998 Webber SE;Okano K;Little TL;Reich SH;Xin Y;Fuhrman SA;Matthews DA;Love RA;Hendrickson TF;Patick AK;Meador JW 3rd;Ferre RA;Brown EL;Ford CE;Binford SL;Worland ST View More
9667970 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies. J Med Chem 1998 Dragovich PS;Webber SE;Babine RE;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Reich SH;Prins TJ;Marakovits JT;Littlefield ES;Zhou R;Tikhe J;Ford CE;Wallace MB;Meador JW 3rd;Ferre RA;Brown EL;Binford SL;Harr JE;DeLisle DM;Worland ST View More
9667971 Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 2. Peptide structure-activity studies. J Med Chem 1998 Dragovich PS;Webber SE;Babine RE;Fuhrman SA;Patick AK;Matthews DA;Reich SH;Marakovits JT;Prins TJ;Zhou R;Tikhe J;Littlefield ES;Bleckman TM;Wallace MB;Little TL;Ford CE;Meador JW 3rd;Ferre RA;Brown EL;Binford SL;DeLisle DM;Worland ST View More
9865389 Anti-picornavirus activity of synthetic flavon-3-yl esters. Antivir Chem Chemother 1998 Conti C;Mastromarino P;Sgro R;Desideri N View More
9875381 Approaches to antiviral chemotherapy for acute respiratory infections. Antivir Chem Chemother 1998 Shigeta S View More