PMID Title Journal Publication Year Author View in RVdb
10771083 Anti-rhinovirus activity of 3-methylthio-5-aryl-4-isothiazolecarbonitrile derivatives. Antiviral Res 2000 Garozzo A;Cutri CC;Castro A;Tempera G;Guerrera F;Sarva MC;Geremia E View More
10950388 Antiviral therapy for enteroviruses and rhinoviruses. Antivir Chem Chemother 2000 Rotbart HA View More
11302940 Liquid chromatography-mass spectrometry and liquid chromatography-NMR characterization of in vitro metabolites of a potent and irreversible peptidomimetic inhibitor of rhinovirus 3C protease. Drug Metab Dispos 2001 Zhang KE;Hee B;Lee CA;Liang B;Potts BC View More
11900346 Peptidyl diazomethyl ketones inhibit the human rhinovirus 3C protease: effect on virus yield by partial block of P3 polyprotein processing. Antivir Chem Chemother 2001 Murray MA;Janc JW;Venkatraman S;Babe LM View More
12103435 Synthesis of new 3-methylthio-5-aryl-4-isothiazolecarbonitriles with broad antiviral spectrum. Antiviral Res 2002 Cutri CC;Garozzo A;Siracusa MA;Castro A;Tempera G;Sarva MC;Guerrera F View More
1318383 Binding of an antiviral agent to a sensitive and a resistant human rhinovirus. Computer simulation studies with sampling of amino acid side-chain conformation. I. Mapping the rotamers of residue 188 of viral protein 1. J Mol Biol 1992 Wade RC;McCammon JA View More
1335079 Antirhinoviral activity of heterocyclic analogs of Win 54954. J Med Chem 1992 Bailey TR;Diana GD;Kowalczyk PJ;Akullian V;Eissenstat MA;Cutcliffe D;Mallamo JP;Carabateas PM;Pevear DC View More
14582848 Synthesis and evaluation of antirhinovirus activity of 3-hydroxy and 3-methoxy 2-styrylchromones. Antivir Chem Chemother 2003 Desideri N;Mastromarino P;Conti C View More
15168795 An optical thin film assay incorporating rhinovirus protease inhibitors as detector reagents. Antiviral Res 2004 Ettinger A;Ostroff R;Rhihanek M;Dragovich PS;Zalman LS;Patick AK;Prins TJ;Fuhrman SA;Brown EL;Worland ST;Polisky B View More
15168800 Mode of action of 2-furylmercury chloride, an anti-rhinovirus compound. Antiviral Res 2004 Verheyden B;Andries K;Rombaut B View More
15743897 Novel [(biphenyloxy)propyl]isoxazole derivatives for inhibition of human rhinovirus 2 and coxsackievirus B3 replication. J Antimicrob Chemother 2005 Makarov VA;Riabova OB;Granik VG;Wutzler P;Schmidtke M View More
15943481 BRUTUS: optimization of a grid-based similarity function for rigid-body molecular superposition. 1. Alignment and virtual screening applications. J Med Chem 2005 Tervo AJ;Ronkko T;Nyronen TH;Poso A View More
16130524 Synthesis and anti-rhinovirus properties of fluoro-substituted flavonoids. Antivir Chem Chemother 2005 Conti C;Mastromarino P;Goldoni P;Portalone G;Desideri N View More
1668301 Enantiomeric separation of substituted flavanoids by LC-DAD. J Pharm Biomed Anal 1991 Quaglia MG;Desideri N;Bossu E;Melchiorre P;Conti C View More
1699132 Structural and serological evidence for a novel mechanism of antigenic variation in foot-and-mouth disease virus. Nature 1990 Parry N;Fox G;Rowlands D;Brown F;Fry E;Acharya R;Logan D;Stuart D View More
17045322 Understanding human rhinovirus infections in terms of QSAR. Virology 2007 Verma RP;Hansch C View More
17665898 Quantitative structure-activity relationship studies of [(biphenyloxy)propyl]isoxazole derivatives. Inhibitors of human rhinovirus 2 replication. J Med Chem 2007 Kuz'min VE;Artemenko AG;Muratov EN;Volineckaya IL;Makarov VA;Riabova OB;Wutzler P;Schmidtke M View More
18046960 Isothiazole derivatives as antiviral agents. Antivir Chem Chemother 2007 Garozzo A;Cutri CC;Pannecouque C;Castro A;Guerrera F;De Clercq E View More
1846916 Synthesis and antirhinovirus activity of 8-substituted analogues of 6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine. J Med Chem 1991 Kelley JL;Linn JA;Selway JW View More
18583140 Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents. Bioorg Med Chem 2008 Kuo CJ;Shie JJ;Fang JM;Yen GR;Hsu JT;Liu HG;Tseng SN;Chang SC;Lee CY;Shih SR;Liang PH View More
1965654 Structure and in vitro antiviral activity of sesquiterpene glycosides from Calendula arvensis. J Nat Prod 1990 De Tommasi N;Pizza C;Conti C;Orsi N;Stein ML View More
2006420 The three-dimensional structure of canine parvovirus and its functional implications. Science 1991 Tsao J;Chapman MS;Agbandje M;Keller W;Smith K;Wu H;Luo M;Smith TJ;Rossmann MG;Compans RW;et al. View More
20200313 In situ assembly of macromolecular complexes triggered by light. Proc Natl Acad Sci U S A 2010 Grunwald C;Schulze K;Reichel A;Weiss VU;Blaas D;Piehler J;Wiesmuller KH;Tampe R View More
21401523 Protein-cation interactions: structural and thermodynamic aspects. Curr Protein Pept Sci 2011 Arias-Moreno X;Abian O;Vega S;Sancho J;Velazquez-Campoy A View More
2163455 Synthesis, antitumor activity, and antiviral activity of 3-substituted 3-deazacytidines and 3-substituted 3-deazauridines. J Med Chem 1990 McNamara DJ;Cook PD;Allen LB;Kehoe MJ;Holland CS;Teepe AG View More
21936817 Recent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery. Biochem Soc Trans 2011 Ramajayam R;Tan KP;Liang PH View More
22332366 [Synthesis of A-secomethylenamino- and substituted amidoximotriterpenoids]. Bioorg Khim 2011 Kazakova OB;Giniiatullina GV;Tolstikov GA View More
23170079 Anti-human rhinoviral activity of polybromocatechol compounds isolated from the rhodophyta, Neorhodomela aculeata. Mar Drugs 2012 Park SH;Song JH;Kim T;Shin WS;Park GM;Lee S;Kim YJ;Choi P;Kim H;Kim HS;Kwon DH;Choi HJ;Ham J View More
23726345 Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus. Bioorg Med Chem Lett 2013 Decor A;Grand-Maitre C;Hucke O;O'Meara J;Kuhn C;Constantineau-Forget L;Brochu C;Malenfant E;Bertrand-Laperle M;Bordeleau J;Ghiro E;Pesant M;Fazal G;Gorys V;Little M;Boucher C;Bordeleau S;Turcotte P;Guo T;Garneau M;Spickler C;Gauthier A View More
23896472 A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIbeta. Antimicrob Agents Chemother 2013 van der Schaar HM;Leyssen P;Thibaut HJ;de Palma A;van der Linden L;Lanke KH;Lacroix C;Verbeken E;Conrath K;Macleod AM;Mitchell DR;Palmer NJ;van de Poel H;Andrews M;Neyts J;van Kuppeveld FJ View More
24346589 Synthesis of the 2-methylene analogue of the HRV 3C protease inhibitor thysanone (2-carbathysanone). Org Biomol Chem 2014 Schunemann K;Furkert DP;Choi EC;Connelly S;Fraser JD;Sperry J;Brimble MA View More
2542566 Genetic and molecular analyses of spontaneous mutants of human rhinovirus 14 that are resistant to an antiviral compound. J Virol 1989 Heinz BA;Rueckert RR;Shepard DA;Dutko FJ;McKinlay MA;Fancher M;Rossmann MG;Badger J;Smith TJ View More
2555523 Crystal structure of human rhinovirus serotype 1A (HRV1A). J Mol Biol 1989 Kim SS;Smith TJ;Chapman MS;Rossmann MC;Pevear DC;Dutko FJ;Felock PJ;Diana GD;McKinlay MA View More
2558377 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses. Proteins 1989 Badger J;Minor I;Oliveira MA;Smith TJ;Rossmann MG View More
26372075 Synthesis and antiviral activity of maleopimaric and quinopimaric acids\' derivatives. Bioorg Med Chem 2015 Tretyakova EV;Smirnova IE;Salimova EV;Odinokov VN View More
27007360 A New Megastigmane Sesquiterpenoid from Zanthoxylum Schinifolium Sieb. et Zucc. Molecules 2016 Hu L;Wang K;Wang Z;Liu J;Wang K;Zhang J;Luo Z;Xue Y;Zhang Y;Zhang Y View More
27090557 Purine analogs as phosphatidylinositol 4-kinase IIIbeta inhibitors. Bioorg Med Chem Lett 2016 Sala M;Kogler M;Plackova P;Mejdrova I;Hrebabecky H;Prochazkova E;Strunin D;Lee G;Birkus G;Weber J;Mertlikova-Kaiserova H;Nencka R View More
27265257 Design and structure-activity relationships of novel inhibitors of human rhinovirus 3C protease. Bioorg Med Chem Lett 2016 Kawatkar SP;Gagnon M;Hoesch V;Tiong-Yip C;Johnson K;Ek M;Nilsson E;Lister T;Olsson L;Patel J;Yu Q View More
27647011 Antiviral activities of compounds from aerial parts of Salvia plebeia R. Br. J Ethnopharmacol 2016 Bang S;Quy Ha TK;Lee C;Li W;Oh WK;Shim SH View More
28004945 Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIbeta (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology. J Med Chem 2017 Mejdrova I;Chalupska D;Plackova P;Muller C;Sala M;Klima M;Baumlova A;Hrebabecky H;Prochazkova E;Dejmek M;Strunin D;Weber J;Lee G;Matousova M;Mertlikova-Kaiserova H;Ziebuhr J;Birkus G;Boura E;Nencka R View More
2845659 Prediction of three-dimensional models for foot-and-mouth disease virus and hepatitis A virus. Virology 1988 Luo M;Rossmann MG;Palmenberg AC View More
2856083 The use of molecular-replacement phases for the refinement of the human rhinovirus 14 structure. Acta Crystallogr A 1988 Arnold E;Rossmann MG View More
28581749 A Novel Series of Highly Potent Small Molecule Inhibitors of Rhinovirus Replication. J Med Chem 2017 Kim J;Jung YK;Kim C;Shin JS;Scheers E;Lee JY;Han SB;Lee CK;Neyts J;Ha JD;Jung YS View More
28778471 Design, synthesis and evaluation of 2,2-dimethyl-1,3-dioxolane derivatives as human rhinovirus 3C protease inhibitors. Bioorg Med Chem Lett 2017 Zhang Q;Cao R;Liu A;Lei S;Li Y;Yang J;Li S;Xiao J View More
28914420 Labdane-type diterpenoids from Vitex limonifolia and their antivirus activities. J Nat Med 2018 Ban NK;Thoa NTK;Linh TM;Trang DT;Van Kiem P;Nhiem NX;Tai BH;Van Minh C;Song JH;Ko HJ;Kim SH View More
29039946 Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders. J Nat Prod 2017 Fois B;Bianco G;Sonar VP;Distinto S;Maccioni E;Meleddu R;Melis C;Marras L;Pompei R;Floris C;Caboni P;Cottiglia F View More
29562753 Nucleosides for the treatment of respiratory RNA virus infections. Antivir Chem Chemother 2018 Jordan PC;Stevens SK;Deval J View More
29760414 Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem 2018 Mousnier A;Bell AS;Swieboda DP;Morales-Sanfrutos J;Perez-Dorado I;Brannigan JA;Newman J;Ritzefeld M;Hutton JA;Guedan A;Asfor AS;Robinson SW;Hopkins-Navratilova I;Wilkinson AJ;Johnston SL;Leatherbarrow RJ;Tuthill TJ;Solari R;Tate EW View More
29866517 Identification of quinone analogues as potential inhibitors of picornavirus 3C protease in vitro. Bioorg Med Chem Lett 2018 Jung E;Lee JY;Kim HJ;Ryu CK;Lee KI;Kim M;Lee CK;Go YY View More
30153009 Structure-Based Drug Design of Potent Pyrazole Derivatives against Rhinovirus Replication. J Med Chem 2018 Da Costa L;Scheers E;Coluccia A;Casulli A;Roche M;Di Giorgio C;Neyts J;Terme T;Cirilli R;La Regina G;Silvestri R;Mirabelli C;Vanelle P View More
30153588 Unusual ent-atisane type diterpenoids with 2-oxopropyl skeleton from the roots of Euphorbia ebracteolata and their antiviral activity against human rhinovirus 3 and enterovirus 71. Bioorg Chem 2018 Wang B;Wei Y;Zhao X;Tian X;Ning J;Zhang B;Deng S;Li D;Ma X;Wang C View More
30646829 Good and bad molecular fingerprints for human rhinovirus 3C protease inhibition: identification, validation, and application in designing of new inhibitors through Monte Carlo-based QSAR study. J Biomol Struct Dyn 2020 Jain S;Amin SA;Adhikari N;Jha T;Gayen S View More
30844608 New 4-phenylcoumarin derivatives as potent 3C protease inhibitors: Design, synthesis, anti-HAV effect and molecular modeling. Eur J Med Chem 2019 Kassem AF;Batran RZ;Abbas EMH;Elseginy SA;Shaheen MNF;Elmahdy EM View More
31203807 Thiazole Compounds as Antiviral Agents: An Update. Med Chem 2020 Singh IP;Gupta S;Kumar S View More
31226653 Back to the future: Advances in development of broad-spectrum capsid-binding inhibitors of enteroviruses. Eur J Med Chem 2019 Egorova A;Ekins S;Schmidtke M;Makarov V View More
31462495 Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site. Proc Natl Acad Sci U S A 2019 Wald J;Pasin M;Richter M;Walther C;Mathai N;Kirchmair J;Makarov VA;Goessweiner-Mohr N;Marlovits TC;Zanella I;Real-Hohn A;Verdaguer N;Blaas D;Schmidtke M View More
31808979 Discovery of N-pyridoyl-Delta(2) -pyrazolines as Hsp90 inhibitors. Arch Pharm (Weinheim) 2020 Kadasi S;Yerroju R;Gaddam S;Pullanagiri N;Chary M;Pingili D;Raj S;Raghavendra NM View More
31881489 Novel pleconaril derivatives: Influence of substituents in the isoxazole and phenyl rings on the antiviral activity against enteroviruses. Eur J Med Chem 2020 Egorova A;Kazakova E;Jahn B;Ekins S;Makarov V;Schmidtke M View More
33872498 Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2. J Med Chem 2022 Dai W;Jochmans D;Xie H;Yang H;Li J;Su H;Chang D;Wang J;Peng J;Zhu L;Nian Y;Hilgenfeld R;Jiang H;Chen K;Zhang L;Xu Y;Neyts J;Liu H View More
33932782 Sub-structure-based screening and molecular docking studies of potential enteroviruses inhibitors. Comput Biol Chem 2021 James SA;Yam WK View More
34077853 A CDR-based approach to generate covalent inhibitory antibody for human rhinovirus protease. Bioorg Med Chem 2021 Cheng Y;Wu J;Han Y;Xu J;Da Y;Zhao Q;Guo G;Zhou Y;Chen Y;Liu J;Chen H;Jiang X;Cai X View More
36749598 Crotofolane Diterpenoids and Other Constituents Isolated from Croton kilwae. J Nat Prod 2023 Mahambo ET;Uwamariya C;Miah M;Clementino LDC;Alvarez LCS;Di Santo Meztler GP;Trybala E;Said J;Wieske LHE;Ward JS;Rissanen K;Munissi JJE;Costa FTM;Sunnerhagen P;Bergstrom T;Nyandoro SS;Erdelyi M View More
7515772 Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein. Cell 1994 Matthews DA;Smith WW;Ferre RA;Condon B;Budahazi G;Sisson W;Villafranca JE;Janson CA;McElroy HE;Gribskov CL;et al. View More
7820548 Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design. Curr Biol 1994 Grant RA;Hiremath CN;Filman DJ;Syed R;Andries K;Hogle JM View More
7919786 Protein structure--based drug design. Annu Rev Biophys Biomol Struct 1994 Whittle PJ;Blundell TL View More
8009848 Human rhinovirus 14 complexed with fragments of active antiviral compounds. Virology 1994 Bibler-Muckelbauer JK;Kremer MJ;Rossmann MG;Diana GD;Dutko FJ;Pevear DC;McKinlay MA View More
8246217 On the mechanism of HRV-14 antiviral compounds: "slow growth" as a conformational search procedure. J Med Chem 1993 Guha-Biswas M;Holder M;Pettitt BM View More
8384042 Mapping the surface properties of macromolecules. Protein Sci 1993 Chapman MS View More
8386772 Structure determination of antiviral compound SCH 38057 complexed with human rhinovirus 14. J Mol Biol 1993 Zhang A;Nanni RG;Li T;Arnold GF;Oren DA;Jacobo-Molina A;Williams RL;Kamer G;Rubenstein DA;Li Y;et al. View More
8397301 The use of an algorithmic method for small molecule superimpositions in the design of antiviral agents. J Comput Aided Mol Des 1993 Diana G;Jaeger EP;Peterson ML;Treasurywala AM View More
8583283 Studies on photoinactivation by various phthalocyanines of a free or replicating non-enveloped virus. J Photochem Photobiol B 1995 Gaspard S;Tempete C;Werner GH View More
8612574 Structure of a neutralizing antibody bound bivalently to human rhinovirus 2. EMBO J 1996 Hewat EA;Blaas D View More
8834767 Intercellular adhesion molecule-1. J Mol Med (Berl) 1996 van de Stolpe A;van der Saag PT View More
8978838 Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease. J Med Chem 1996 Webber SE;Tikhe J;Worland ST;Fuhrman SA;Hendrickson TF;Matthews DA;Love RA;Patick AK;Meador JW;Ferre RA;Brown EL;DeLisle DM;Ford CE;Binford SL View More
9079380 Structure-based design of peptide presentation on a viral surface: the crystal structure of a plant/animal virus chimera at 2.8 A resolution. Fold Des 1996 Lin T;Porta C;Lomonossoff G;Johnson JE View More
9341923 Synthesis and antiviral activity of C2 analogs of enviroxime: an exploration of the role of critical functionality. J Med Chem 1997 Victor F;Loncharich R;Tang J;Spitzer WA View More
9865389 Anti-picornavirus activity of synthetic flavon-3-yl esters. Antivir Chem Chemother 1998 Conti C;Mastromarino P;Sgro R;Desideri N View More