PMID Title Journal Publication Year Author View in RVdb
11302940 Liquid chromatography-mass spectrometry and liquid chromatography-NMR characterization of in vitro metabolites of a potent and irreversible peptidomimetic inhibitor of rhinovirus 3C protease. Drug Metab Dispos 2001 Zhang KE;Hee B;Lee CA;Liang B;Potts BC View More
15921461 Human rhinovirus 3C protease: generation of pharmacophore models for peptidic and nonpeptidic inhibitors and their application in virtual screening. J Chem Inf Model 2005 Steindl T;Laggner C;Langer T View More
21936817 Recent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery. Biochem Soc Trans 2011 Ramajayam R;Tan KP;Liang PH View More
23388726 3C protease of enterovirus 68: structure-based design of Michael acceptor inhibitors and their broad-spectrum antiviral effects against picornaviruses. J Virol 2013 Tan J;George S;Kusov Y;Perbandt M;Anemuller S;Mesters JR;Norder H;Coutard B;Lacroix C;Leyssen P;Neyts J;Hilgenfeld R View More
23549610 The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles\' heel": current effective inhibitor targeting a 3C-like protease. Protein Cell 2013 Ren Z;Yan L;Zhang N;Guo Y;Yang C;Lou Z;Rao Z View More
26055377 The enterovirus 3C protease inhibitor SG85 efficiently blocks rhinovirus replication and is not cross-resistant with rupintrivir. Antimicrob Agents Chemother 2015 Lacroix C;George S;Leyssen P;Hilgenfeld R;Neyts J View More
27645381 Antiviral activities of peptide-based covalent inhibitors of the Enterovirus 71 3C protease. Sci Rep 2016 Tan YW;Ang MJ;Lau QY;Poulsen A;Ng FM;Then SW;Peng J;Hill J;Hong WJ;Chia CS;Chu JJ View More
30352199 Development of a homogeneous time-resolved fluorescence assay for detection of viral double-stranded RNA. Anal Biochem 2019 Fujita M;Adachi K;Nagasawa M View More
30646829 Good and bad molecular fingerprints for human rhinovirus 3C protease inhibition: identification, validation, and application in designing of new inhibitors through Monte Carlo-based QSAR study. J Biomol Struct Dyn 2020 Jain S;Amin SA;Adhikari N;Jha T;Gayen S View More
33515606 Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development. Antiviral Res 2021 Liu C;Boland S;Scholle MD;Bardiot D;Marchand A;Chaltin P;Blatt LM;Beigelman L;Symons JA;Raboisson P;Gurard-Levin ZA;Vandyck K;Deval J View More
33641023 Structure-activity relationship (SAR) and molecular dynamics study of withaferin-A fragment derivatives as potential therapeutic lead against main protease (M(pro)) of SARS-CoV-2. J Mol Model 2021 Ghosh A;Chakraborty M;Chandra A;Alam MP View More
34960671 RIPK1 Is Cleaved by 3C Protease of Rhinovirus A and B Strains and Minor and Major Groups. Viruses 2021 Croft SN;Walker EJ;Ghildyal R View More
35278580 Label-free duplex SAMDI-MS screen reveals novel SARS-CoV-2 3CLpro inhibitors. Antiviral Res 2022 Scholle MD;O'Kane PT;Dib S;Gurard-Levin ZA View More
7794931 Peptide aldehyde inhibitors of hepatitis A virus 3C proteinase. Biochemistry 1995 Malcolm BA;Lowe C;Shechosky S;McKay RT;Yang CC;Shah VJ;Simon RJ;Vederas JC;Santi DV View More
7919786 Protein structure--based drug design. Annu Rev Biophys Biomol Struct 1994 Whittle PJ;Blundell TL View More
8698636 Novel triterpene sulfates from Fusarium compactum using a rhinovirus 3C protease inhibitor screen. J Antibiot (Tokyo) 1996 Brill GM;Kati WM;Montgomery D;Karwowski JP;Humphrey PE;Jackson M;Clement JJ;Kadam S;Chen RH;McAlpine JB View More
9989947 Inhibition of 3C protease from human rhinovirus strain 1B by peptidyl bromomethylketonehydrazides. Arch Biochem Biophys 1999 Kati WM;Sham HL;McCall JO;Montgomery DA;Wang GT;Rosenbrook W;Miesbauer L;Buko A;Norbeck DW View More