PMID Title Journal Publication Year Author View in RVdb
10534191 Lack of induction by rhinoviruses of systemic type I interferon production or enhanced MxA protein expression during the common cold. Eur J Clin Microbiol Infect Dis 1999 Makela MJ;Halminen M;Ruuskanen O;Puhakka T;Pirhonen J;Julkunen I;Ilonen J View More
11142632 Spectrum of virus inhibition by consensus interferon YM643. Antivir Chem Chemother 2000 Yasuda S;Huffman JH;Smee DF;Sidwell RW;Miyata K View More
16275487 Recombinant interferon alpha treatment decreases heart rate variability indices and impairs exercise tolerance in patients with chronic hepatitis. Biomed Pharmacother 2005 Takase B;Hamabe A;Uehata A;Hujioka T;Kondo T;Matsui T;Ohsuzu F;Ishihara M View More
16289761 New treatment regimes for virus-induced exacerbations of asthma. Pulm Pharmacol Ther 2006 Edwards MR;Kebadze T;Johnson MW;Johnston SL View More
16641293 Human rhinovirus attenuates the type I interferon response by disrupting activation of interferon regulatory factor 3. J Virol 2006 Peng T;Kotla S;Bumgarner RE;Gustin KE View More
17020930 Human rhinovirus induces robust IP-10 release by monocytic cells, which is independent of viral replication but linked to type I interferon receptor ligation and STAT1 activation. J Leukoc Biol 2006 Korpi-Steiner NL;Bates ME;Lee WM;Hall DJ;Bertics PJ View More
1723372 The use of interferon-alpha in virus infections. Drugs 1991 Finter NB;Chapman S;Dowd P;Johnston JM;Manna V;Sarantis N;Sheron N;Scott G;Phua S;Tatum PB View More
1750016 Prophylactic intranasal alpha 2 interferon and viral exacerbations of chronic respiratory disease. Thorax 1991 Wiselka MJ;Nicholson KG;Kent J;Cookson JB;Tyrrell DA View More
18234348 Understanding the mechanisms of viral induced asthma: new therapeutic directions. Pharmacol Ther 2008 Hansbro NG;Horvat JC;Wark PA;Hansbro PM View More
18272195 Attenuation of the type I interferon response in cells infected with human rhinovirus. Virology 2008 Kotla S;Peng T;Bumgarner RE;Gustin KE View More
19168696 Transforming growth factor-beta enhances rhinovirus infection by diminishing early innate responses. Am J Respir Cell Mol Biol 2009 Thomas BJ;Lindsay M;Dagher H;Freezer NJ;Li D;Ghildyal R;Bardin PG View More
19211759 Proteinase 2Apro is essential for enterovirus replication in type I interferon-treated cells. J Virol 2009 Morrison JM;Racaniello VR View More
19734213 The ssRNA genome of human rhinovirus induces a type I IFN response but fails to induce maturation in human monocyte-derived dendritic cells. J Immunol 2009 Schrauf C;Kirchberger S;Majdic O;Seyerl M;Zlabinger GJ;Stuhlmeier KM;Sachet M;Seipelt J;Stockl J View More
21224721 Human rhinovirus recognition in non-immune cells is mediated by Toll-like receptors and MDA-5, which trigger a synergetic pro-inflammatory immune response. Virulence 2011 Triantafilou K;Vakakis E;Richer EA;Evans GL;Villiers JP;Triantafilou M View More
21971992 The type I interferon response during viral infections: a "SWOT" analysis. Rev Med Virol 2012 Gaajetaan GR;Bruggeman CA;Stassen FR View More
22213737 Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells. Thorax 2012 Vareille M;Kieninger E;Alves MP;Kopf BS;Moller A;Geiser T;Johnston SL;Edwards MR;Regamey N View More
23154939 Asthma exacerbations: a molecular dichotomy between antiviral and pro-inflammatory responses revealed. EMBO Mol Med 2012 Andreakos E View More
23165884 Defining critical roles for NF-kappaB p65 and type I interferon in innate immunity to rhinovirus. EMBO Mol Med 2012 Bartlett NW;Slater L;Glanville N;Haas JJ;Caramori G;Casolari P;Clarke DL;Message SD;Aniscenko J;Kebadze T;Zhu J;Mallia P;Mizgerd JP;Belvisi M;Papi A;Kotenko SV;Johnston SL;Edwards MR View More
24428709 Modulation of airway epithelial antiviral immunity by fungal exposure. Am J Respir Cell Mol Biol 2014 Zhu L;Lee B;Zhao F;Zhou X;Chin V;Ling SC;Chen Y View More
24472849 IL-15 complexes induce NK- and T-cell responses independent of type I IFN signaling during rhinovirus infection. Mucosal Immunol 2014 Jayaraman A;Jackson DJ;Message SD;Pearson RM;Aniscenko J;Caramori G;Mallia P;Papi A;Shamji B;Edwards M;Westwick J;Hansel T;Stanciu LA;Johnston SL;Bartlett NW View More
24636264 Viral infections in asthma and COPD. Respir Investig 2014 Matsumoto K;Inoue H View More
2543280 Ineffectiveness of postexposure prophylaxis of rhinovirus infection with low-dose intranasal alpha 2b interferon in families. Antimicrob Agents Chemother 1989 Monto AS;Schwartz SA;Albrecht JK View More
2545792 Comparative susceptibility of respiratory viruses to recombinant interferons-alpha 2b and -beta. J Interferon Res 1989 Sperber SJ;Hayden FG View More
25459580 Asthma: the interplay between viral infections and allergic diseases. Immunol Allergy Clin North Am 2015 Rowe RK;Gill MA View More
2551976 Ineffectiveness of recombinant interferon-beta serine nasal drops for prophylaxis of natural colds. J Infect Dis 1989 Sperber SJ;Levine PA;Sorrentino JV;Riker DK;Hayden FG View More
2552975 Use of alpha-2-interferon nasal spray for prophylactic reduction of rhinovirus-induced infection in mission-critical groups. Aviat Space Environ Med 1989 Morey WA;Blackwell OG View More
27836899 TRAIL signaling is proinflammatory and proviral in a murine model of rhinovirus 1B infection. Am J Physiol Lung Cell Mol Physiol 2017 Girkin JL;Hatchwell LM;Collison AM;Starkey MR;Hansbro PM;Yagita H;Foster PS;Mattes J View More
28122977 Impact of Type I Interferon on the Safety and Immunogenicity of an Experimental Live-Attenuated Herpes Simplex Virus 1 Vaccine in Mice. J Virol 2017 Royer DJ;Carr MM;Chucair-Elliott AJ;Halford WP;Carr DJJ View More
28192616 Association of ORMDL3 with rhinovirus-induced endoplasmic reticulum stress and type I Interferon responses in human leucocytes. Clin Exp Allergy 2017 Liu YP;Rajamanikham V;Baron M;Patel S;Mathur SK;Schwantes EA;Ober C;Jackson DJ;Gern JE;Lemanske RF Jr;Smith JA View More
28228588 Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication. J Virol 2017 Guedan A;Swieboda D;Charles M;Toussaint M;Johnston SL;Asfor A;Panjwani A;Tuthill TJ;Danahay H;Raynham T;Mousnier A;Solari R View More
2831814 Demonstration of dose-response relationship in seasonal prophylaxis of respiratory infections with alpha-2b interferon. Antimicrob Agents Chemother 1988 Monto AS;Albrecht JK;Schwartz SA View More
2834996 Intranasal recombinant alfa-2b interferon treatment of naturally occurring common colds. Antimicrob Agents Chemother 1988 Hayden FG;Kaiser DL;Albrecht JK View More
2839579 Tolerance and efficacy of intranasal administration of recombinant beta serine interferon in healthy adults. J Infect Dis 1988 Sperber SJ;Levine PA;Innes DJ;Mills SE;Hayden FG View More
2852485 Intranasal tolerance and histopathologic effects of a novel synthetic interferon, rIFN-alpha Con1. Antiviral Res 1988 Hayden FG;Innes DJ Jr;Mills SE;Levine PA View More
28576493 The suppression of innate immune response by human rhinovirus C. Biochem Biophys Res Commun 2017 Pang LL;Yuan XH;Shao CS;Li MZ;Wang Y;Wang HM;Xie GC;Xie ZP;Yuan Y;Zhou DM;Sun XM;Zhang Q;Xin Y;Li DD;Duan ZJ View More
29228279 In Vitro Model of Fully Differentiated Human Nasal Epithelial Cells Infected With Rhinovirus Reveals Epithelium-Initiated Immune Responses. J Infect Dis 2018 Tan KS;Ong HH;Yan Y;Liu J;Li C;Ong YK;Thong KT;Choi HW;Wang DY;Chow VT View More
29486764 Impaired type I interferon regulation in the blood transcriptome of recurrent asthma exacerbations. BMC Med Genomics 2018 Gomez JL;Diaz MP;Nino G;Britto CJ View More
2982972 Intranasal interferon-alpha 2 prophylaxis of natural respiratory virus infection. J Infect Dis 1985 Douglas RM;Albrecht JK;Miles HB;Moore BW;Read R;Worswick DA;Woodward AJ View More
2996687 Rhinovirus colds. Br Med Bull 1985 Phillpotts RJ;Tyrrell DA View More
2997387 Tolerance of one-month intranasal interferon. J Med Virol 1985 Scott GM;Onwubalili JK;Robinson JA;Dore C;Secher DS;Cantell K View More
29997212 Engineered Oncolytic Poliovirus PVSRIPO Subverts MDA5-Dependent Innate Immune Responses in Cancer Cells. J Virol 2018 Walton RW;Brown MC;Sacco MT;Gromeier M View More
3001518 Prophylactic efficacy of intranasal alpha 2-interferon against rhinovirus infections in the family setting. N Engl J Med 1986 Douglas RM;Moore BW;Miles HB;Davies LM;Graham NM;Ryan P;Worswick DA;Albrecht JK View More
3001519 Prevention of natural colds by contact prophylaxis with intranasal alpha 2-interferon. N Engl J Med 1986 Hayden FG;Albrecht JK;Kaiser DL;Gwaltney JM Jr View More
3011917 Intranasal interferon-alpha 2b for seasonal prophylaxis of respiratory infection. J Infect Dis 1986 Monto AS;Shope TC;Schwartz SA;Albrecht JK View More
3014018 Interferon-beta ser as prophylaxis against experimental rhinovirus infection in volunteers. J Interferon Res 1986 Higgins PG;Al-Nakib W;Willman J;Tyrrell DA View More
3016111 Prevention of experimental coronavirus colds with intranasal alpha-2b interferon. J Infect Dis 1986 Turner RB;Felton A;Kosak K;Kelsey DK;Meschievitz CK View More
3017203 Synergism between anti-rhinovirus antivirals: various human interferons and a number of synthetic compounds. Antiviral Res 1986 Ahmad AL;Tyrrell DA View More
3025154 The efficacy and tolerance of intranasal interferons: studies at the Common Cold Unit. J Antimicrob Chemother 1986 Tyrrell DA View More
3028312 [Rhinovirus and acute respiratory infections in infants]. Arch Fr Pediatr 1986 Freymuth F;Quibriac M;Petitjean J;Pierre C;Duhamel JF;Denis A;Legoas C View More
30296526 Interferon-induced epithelial response to rhinovirus 16 in asthma relates to inflammation and FEV1. J Allergy Clin Immunol 2019 Ravi A;Koster J;Dijkhuis A;Bal SM;Sabogal Pineros YS;Bonta PI;Majoor CJ;Sterk PJ;Lutter R View More
31319869 MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling. Cell Commun Signal 2019 Baturcam E;Vollmer S;Schluter H;Maciewicz RA;Kurian N;Vaarala O;Ludwig S;Cunoosamy DM View More
31693592 New immunodeficiency syndromes that help us understand the IFN-mediated antiviral immune response. Curr Opin Pediatr 2019 Jing H;Su HC View More
31988324 Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity. Nat Commun 2020 Mosaheb MM;Dobrikova EY;Brown MC;Yang Y;Cable J;Okada H;Nair SK;Bigner DD;Ashley DM;Gromeier M View More
3215290 A study of intranasally administered interferon A (rIFN-alpha 2A) for the seasonal prophylaxis of natural viral infections of the upper respiratory tract in healthy volunteers. Epidemiol Infect 1988 Tannock GA;Gillett SM;Gillett RS;Barry RD;Hensley MJ;Herd R;Reid AL;Saunders NA View More
3232968 Failure to demonstrate synergy between interferon-alpha and a synthetic antiviral, enviroxime, in rhinovirus infections in volunteers. Antiviral Res 1988 Higgins PG;Barrow GI;al-Nakib W;Tyrrell DA;DeLong DC;Lenox-Smith I View More
32383224 IgE-mediated regulation of IL-10 and type I IFN enhances rhinovirus-induced Th2 differentiation by primary human monocytes. Eur J Immunol 2020 Rowe RK;Pyle DM;Farrar JD;Gill MA View More
3303918 Influenza B in households: virus shedding without symptoms or antibody response. Am J Epidemiol 1987 Foy HM;Cooney MK;Allan ID;Albrecht JK View More
33194777 Natural Killer Cells and Host Defense Against Human Rhinoviruses Is Partially Dependent on Type I IFN Signaling. Front Cell Infect Microbiol 2020 van der Heide SL;Xi Y;Upham JW View More
33303556 TLR7/8 regulates type I and type III interferon signalling in rhinovirus 1b-induced allergic asthma. Eur Respir J 2021 Krug J;Kiefer A;Koelle J;Vuorinen T;Xepapadaki P;Stanic B;Chiriac MT;Akdis M;Zimmermann T;Papadopoulos NG;Finotto S View More
33359650 Glucocorticoids impair type I IFN signalling and enhance rhinovirus replication. Eur J Pharmacol 2021 Marcellini A;Swieboda D;Guedan A;Farrow SN;Casolari P;Contoli M;Johnston SL;Papi A;Solari R View More
33444702 Inhibition of coronavirus infection by a synthetic STING agonist in primary human airway system. Antiviral Res 2021 Zhu Q;Zhang Y;Wang L;Yao X;Wu D;Cheng J;Pan X;Liu H;Yan Z;Gao L View More
34160242 Rhinovirus Reduces the Severity of Subsequent Respiratory Viral Infections by Interferon-Dependent and -Independent Mechanisms. mSphere 2021 Van Leuven JT;Gonzalez AJ;Ijezie EC;Wixom AQ;Clary JL;Naranjo MN;Ridenhour BJ;Miller CR;Miura TA View More
34686207 Surfaceome CRISPR screen identifies OLFML3 as a rhinovirus-inducible IFN antagonist. Genome Biol 2021 Mei H;Zha Z;Wang W;Xie Y;Huang Y;Li W;Wei D;Zhang X;Qu J;Liu J View More
35116044 Editorial: Type I and Type III Interferon Immune Responses in Asthma. Front Immunol 2021 Finotto S;Jartti T;Johnston SL View More
3524441 Intranasal interferon (rIFN-alpha A, Ro 22-8181) for contact prophylaxis against common cold: a randomized, double-blind and placebo-controlled field study. Antiviral Res 1986 Herzog C;Berger R;Fernex M;Friesecke K;Havas L;Just M;Dubach UC View More
35265536 Pseudomonas aeruginosa Affects Airway Epithelial Response and Barrier Function During Rhinovirus Infection. Front Cell Infect Microbiol 2022 Endres A;Hugel C;Boland H;Hogardt M;Schubert R;Jonigk D;Braubach P;Rohde G;Bellinghausen C View More
36860857 Hydrogen peroxide attenuates rhinovirus-induced anti-viral interferon secretion in sinonasal epithelial cells. Front Immunol 2023 Lee SH;Han MS;Lee TH;Lee DB;Park JH;Lee SH;Kim TH View More
36895568 Emerging role for interferons in respiratory viral infections and childhood asthma. Front Immunol 2023 Bosco A View More
37087523 Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19. Nat Commun 2023 Radzikowska U;Eljaszewicz A;Tan G;Stocker N;Heider A;Westermann P;Steiner S;Dreher A;Wawrzyniak P;Ruckert B;Rodriguez-Coira J;Zhakparov D;Huang M;Jakiela B;Sanak M;Moniuszko M;O'Mahony L;Jutel M;Kebadze T;Jackson DJ;Edwards MR;Thiel V;Johnston SL;Akdis CA;Sokolowska M View More
37857661 Obesity dysregulates the pulmonary antiviral immune response. Nat Commun 2023 Almond M;Farne HA;Jackson MM;Jha A;Katsoulis O;Pitts O;Tunstall T;Regis E;Dunning J;Byrne AJ;Mallia P;Kon OM;Saunders KA;Simpson KD;Snelgrove RJ;Openshaw PJM;Edwards MR;Barclay WS;Heaney LM;Johnston SL;Singanayagam A View More
4081525 Prevention from naturally acquired viral respiratory infection by interferon nasal spray. Rhinology 1985 Saito H;Takenaka H;Yoshida S;Tsubokawa T;Ogata A;Imanishi F;Imanishi J View More
6089652 Intranasal interferon-alpha 2 for prevention of natural rhinovirus colds. Antimicrob Agents Chemother 1984 Farr BM;Gwaltney JM Jr;Adams KF;Hayden FG View More
6094684 Intranasal lymphoblastoid interferon ("Wellferon") prophylaxis against rhinovirus and influenza virus in volunteers. J Interferon Res 1984 Phillpotts RJ;Higgins PG;Willman JS;Tyrrell DA;Freestone DS;Shepherd WM View More
6299242 Antibody to human leucocyte interferon may enhance the frequency of rhinovirus isolation. Arch Virol 1983 Phillpotts RJ View More
6307140 Anti-interferon antibody increases rhinovirus isolation rates from nasal wash specimens containing interferon-alpha 2. Antiviral Res 1983 Hayden FG;Gwaltney JM Jr View More
6311914 Intranasal interferon alpha 2 for prevention of rhinovirus infection and illness. J Infect Dis 1983 Hayden FG;Gwaltney JM Jr View More
6312877 An effective dosage regimen for prophylaxis against rhinovirus infection by intranasal administration of HuIFN-alpha 2. Antiviral Res 1983 Phillpotts RJ;Scott GM;Higgins PG;Wallace J;Tyrrell DA;Gauci CL View More
6323591 Cell and virus sensitivity studies with recombinant human alpha interferons. J Interferon Res 1983 Kramer MJ;Dennin R;Kramer C;Jones G;Connell E;Rolon N;Gruarin A;Kale R;Trown PW View More
6381610 Intranasal interferon-alpha 2 treatment of experimental rhinoviral colds. J Infect Dis 1984 Hayden FG;Gwaltney JM Jr View More
6381611 Intranasally applied recombinant leukocyte A interferon in normal volunteers. II. Determination of minimal effective and tolerable dose. J Infect Dis 1984 Samo TC;Greenberg SB;Palmer JM;Couch RB;Harmon MW;Johnson PE View More
6400034 The clinical application of fibroblast interferon--an overview. Med Oncol Tumor Pharmacother 1984 Billiau A View More
6619578 Efficacy and tolerance of intranasally applied recombinant leukocyte A interferon in normal volunteers. J Infect Dis 1983 Samo TC;Greenberg SB;Couch RB;Quarles J;Johnson PE;Hook S;Harmon MW View More
6742821 Pharmacokinetics of intranasally applied medication during a cold. Antiviral Res 1984 Phillpotts RJ;Davies HW;Willman J;Tyrrell DA;Higgins PG View More
6763365 Trials of interferon in respiratory infections in man. Tex Rep Biol Med 1981 Greenberg SB;Harmon MW;Tyrrell DA;Scott GM View More