PMID Title Journal Publication Year Author View in RVdb
10098667 Design, synthesis, and evaluation of azapeptides as substrates and inhibitors for human rhinovirus 3C protease. Bioorg Med Chem Lett 1999 Venkatraman S;Kong J;Nimkar S;Wang QM;Aube J;Hanzlik RP View More
10523291 The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis. EMBO J 1999 Petersen JF;Cherney MM;Liebig HD;Skern T;Kuechler E;James MN View More
10716921 Distinct cellular receptor interactions in poliovirus and rhinoviruses. EMBO J 2000 Xing L;Tjarnlund K;Lindqvist B;Kaplan GG;Feigelstock D;Cheng RH;Casasnovas JM View More
11007981 Characterization of the active site thiol group of rhinovirus 2A proteinase. FEBS Lett 2000 Sarkany Z;Skern T;Polgar L View More
11414203 MBP fusion protein with a viral protease cleavage site: one-step cleavage/purification of insoluble proteins. Biotechniques 2001 Alexandrov A;Dutta K;Pascal SM View More
12367717 Biochemical characterization of rhinovirus RNA-dependent RNA polymerase. Antiviral Res 2002 Hung M;Gibbs CS;Tsiang M View More
12515488 Virus-ligand interactions: identification and characterization of ligand binding by NMR spectroscopy. J Am Chem Soc 2003 Benie AJ;Moser R;Bauml E;Blaas D;Peters T View More
12525179 The unusual catalytic triad of poliovirus protease 3C. Biochemistry 2003 Sarkany Z;Polgar L View More
1316450 Determinants of substrate recognition by poliovirus 2A proteinase. J Virol 1992 Hellen CU;Lee CK;Wimmer E View More
1331062 Cleavage specificity on synthetic peptide substrates of human rhinovirus 2 proteinase 2A. J Biol Chem 1992 Sommergruber W;Ahorn H;Zophel A;Maurer-Fogy I;Fessl F;Schnorrenberg G;Liebig HD;Blaas D;Kuechler E;Skern T View More
14530446 RNA cleaving \'10-23\' DNAzymes with enhanced stability and activity. Nucleic Acids Res 2003 Schubert S;Gul DC;Grunert HP;Zeichhardt H;Erdmann VA;Kurreck J View More
15016848 Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro. J Virol 2004 Gradi A;Foeger N;Strong R;Svitkin YV;Sonenberg N;Skern T;Belsham GJ View More
16052286 Cleavage activity of the sapovirus 3C-like protease in Escherichia coli. Arch Virol 2005 Oka T;Katayama K;Ogawa S;Hansman GS;Kageyama T;Miyamura T;Takeda N View More
1654789 Development of synthetic peptide substrates for the poliovirus 3C proteinase. Arch Biochem Biophys 1991 Weidner JR;Dunn BM View More
17007846 Defining residues involved in human rhinovirus 2A proteinase substrate recognition. FEBS Lett 2006 Sousa C;Schmid EM;Skern T View More
17472347 Attachment of VLDL receptors to an icosahedral virus along the 5-fold symmetry axis: multiple binding modes evidenced by fluorescence correlation spectroscopy. Biochemistry 2007 Wruss J;Runzler D;Steiger C;Chiba P;Kohler G;Blaas D View More
17944485 NMR solution structures of the apo and peptide-inhibited human rhinovirus 3C protease (Serotype 14): structural and dynamic comparison. Biochemistry 2007 Bjorndahl TC;Andrew LC;Semenchenko V;Wishart DS View More
1847268 Substrate requirements of a human rhinoviral 2A proteinase. Virology 1991 Skern T;Sommergruber W;Auer H;Volkmann P;Zorn M;Liebig HD;Fessl F;Blaas D;Kuechler E View More
18583140 Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents. Bioorg Med Chem 2008 Kuo CJ;Shie JJ;Fang JM;Yen GR;Hsu JT;Liu HG;Tseng SN;Chang SC;Lee CY;Shih SR;Liang PH View More
21408223 Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity. PLoS One 2011 Rozovics JM;Virgen-Slane R;Semler BL View More
2160953 Substrate requirements of human rhinovirus 3C protease for peptide cleavage in vitro. J Biol Chem 1990 Cordingley MG;Callahan PL;Sardana VV;Garsky VM;Colonno RJ View More
21835805 Differential processing of nuclear pore complex proteins by rhinovirus 2A proteases from different species and serotypes. J Virol 2011 Watters K;Palmenberg AC View More
21871965 An overview of enzymatic reagents for the removal of affinity tags. Protein Expr Purif 2011 Waugh DS View More
22072773 Ex vivo and in vivo inhibition of human rhinovirus replication by a new pseudosubstrate of viral 2A protease. J Virol 2012 Falah N;Violot S;Decimo D;Berri F;Foucault-Grunenwald ML;Ohlmann T;Schuffenecker I;Morfin F;Lina B;Riteau B;Cortay JC View More
22763202 A simple solid phase, peptide-based fluorescent assay for the efficient and universal screening of HRV 3C protease inhibitors. Bioorg Med Chem Lett 2012 Schunemann K;Connelly S;Kowalczyk R;Sperry J;Wilson IA;Fraser JD;Brimble MA View More
23395976 Differential temperature dependence of tobacco etch virus and rhinovirus 3C proteases. Anal Biochem 2013 Raran-Kurussi S;Tozser J;Cherry S;Tropea JE;Waugh DS View More
23580429 Specificity of human rhinovirus 2A(pro) is determined by combined spatial properties of four cleavage site residues. J Gen Virol 2013 Neubauer D;Aumayr M;Gosler I;Skern T View More
24026848 An open conformation determined by a structural switch for 2A protease from coxsackievirus A16. Protein Cell 2013 Sun Y;Wang X;Yuan S;Dang M;Li X;Zhang XC;Rao Z View More
24649897 A new fusion protein platform for quantitatively measuring activity of multiple proteases. Microb Cell Fact 2014 Zhou C;Yan Y;Fang J;Cheng B;Fan J View More
2545915 Chimeric picornavirus polyproteins demonstrate a common 3C proteinase substrate specificity. J Virol 1989 Dewalt PG;Lawson MA;Colonno RJ;Semler BL View More
2555433 Hydrolysis of a series of synthetic peptide substrates by the human rhinovirus 14 3C proteinase, cloned and expressed in Escherichia coli. J Gen Virol 1989 Orr DC;Long AC;Kay J;Dunn BM;Cameron JM View More
2555540 Cleavage of small peptides in vitro by human rhinovirus 14 3C protease expressed in Escherichia coli. J Virol 1989 Cordingley MG;Register RB;Callahan PL;Garsky VM;Colonno RJ View More
2556299 A consensus sequence for substrate hydrolysis by rhinovirus 3C proteinase. FEBS Lett 1989 Long AC;Orr DC;Cameron JM;Dunn BM;Kay J View More
27093053 Activity of the Human Rhinovirus 3C Protease Studied in Various Buffers, Additives and Detergents Solutions for Recombinant Protein Production. PLoS One 2016 Ullah R;Shah MA;Tufail S;Ismat F;Imran M;Iqbal M;Mirza O;Rhaman M View More
2851319 Human rhinovirus 3C protease: cloning and expression of an active form in Escherichia coli. Biochemistry 1988 Libby RT;Cosman D;Cooney MK;Merriam JE;March CJ;Hopp TP View More
29633974 Structural view of the 2A protease from human rhinovirus C15. Acta Crystallogr F Struct Biol Commun 2018 Ling H;Yang P;Hou H;Sun Y View More
2987843 Human rhinovirus 2: complete nucleotide sequence and proteolytic processing signals in the capsid protein region. Nucleic Acids Res 1985 Skern T;Sommergruber W;Blaas D;Gruendler P;Fraundorfer F;Pieler C;Fogy I;Kuechler E View More
30802413 A General Guide for the Optimization of Enzyme Assay Conditions Using the Design of Experiments Approach. SLAS Discov 2019 Onyeogaziri FC;Papaneophytou C View More
31613083 Quantitative Analysis of the Substrate Specificity of Human Rhinovirus 3C Protease and Exploration of Its Substrate Recognition Mechanisms. ACS Chem Biol 2020 Fan X;Li X;Zhou Y;Mei M;Liu P;Zhao J;Peng W;Jiang ZB;Yang S;Iverson BL;Zhang G;Yi L View More
34315103 Defining substrate selection by rhinoviral 2A proteinase through its crystal structure with the inhibitor zVAM.fmk. Virology 2021 Deutschmann-Olek KM;Yue WW;Bezerra GA;Skern T View More
7515772 Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein. Cell 1994 Matthews DA;Smith WW;Ferre RA;Condon B;Budahazi G;Sisson W;Villafranca JE;Janson CA;McElroy HE;Gribskov CL;et al. View More
7782313 Sequence and structural determinants of the interaction between the 5\'-noncoding region of picornavirus RNA and rhinovirus protease 3C. J Biol Chem 1995 Walker PA;Leong LE;Porter AG View More
8057448 Foot-and-mouth disease virus leader proteinase: purification of the Lb form and determination of its cleavage site on eIF-4 gamma. J Virol 1994 Kirchweger R;Ziegler E;Lamphear BJ;Waters D;Liebig HD;Sommergruber W;Sobrino F;Hohenadl C;Blaas D;Rhoads RE;et al. View More
8245010 Human rhinovirus-14 protease 3C (3Cpro) binds specifically to the 5\'-noncoding region of the viral RNA. Evidence that 3Cpro has different domains for the RNA binding and proteolytic activities. J Biol Chem 1993 Leong LE;Walker PA;Porter AG View More
8291255 2A proteinases of coxsackie- and rhinovirus cleave peptides derived from eIF-4 gamma via a common recognition motif. Virology 1994 Sommergruber W;Ahorn H;Klump H;Seipelt J;Zoephel A;Fessl F;Krystek E;Blaas D;Kuechler E;Liebig HD;et al. View More
8338854 Purification of two picornaviral 2A proteinases: interaction with eIF-4 gamma and influence on in vitro translation. Biochemistry 1993 Liebig HD;Ziegler E;Yan R;Hartmuth K;Klump H;Kowalski H;Blaas D;Sommergruber W;Frasel L;Lamphear B;et al. View More
8392608 Inhibition of proteolytic activity of poliovirus and rhinovirus 2A proteinases by elastase-specific inhibitors. J Virol 1993 Molla A;Hellen CU;Wimmer E View More
8520469 The picornaviral 3C proteinases: cysteine nucleophiles in serine proteinase folds. Protein Sci 1995 Malcolm BA View More
8535153 Purification of recombinant human rhinovirus 14 3C protease expressed in Escherichia coli. Protein Expr Purif 1995 Birch GM;Black T;Malcolm SK;Lai MT;Zimmerman RE;Jaskunas SR View More
8787922 Simple in vitro translation assay to analyze inhibitors of rhinovirus proteases. Antimicrob Agents Chemother 1996 Heinz BA;Tang J;Labus JM;Chadwell FW;Kaldor SW;Hammond M View More
8970966 The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase. J Virol 1996 Haghighat A;Svitkin Y;Novoa I;Kuechler E;Skern T;Sonenberg N View More
8972564 Mengo virus 3C proteinase: recombinant expression, intergenus substrate cleavage and localization in vivo. Virus Genes 1996 Hall DJ;Palmenberg AC View More
9207196 Cleavage specificity of human rhinovirus-2 2A protease for peptide substrates. Biochem Biophys Res Commun 1997 Wang QM;Sommergruber W;Johnson RB View More
9328292 Expression and purification of recombinant rhinovirus 14 3CD proteinase and its comparison to the 3C proteinase. Arch Biochem Biophys 1997 Davis GJ;Wang QM;Cox GA;Johnson RB;Wakulchik M;Dotson CA;Villarreal EC View More
9570321 Utilization of a mammalian cell-based RNA binding assay to characterize the RNA binding properties of picornavirus 3C proteinases. RNA 1998 Blair WS;Parsley TB;Bogerd HP;Towner JS;Semler BL;Cullen BR View More
9681985 Development of in vitro peptide substrates for human rhinovirus-14 2A protease. Arch Biochem Biophys 1998 Wang QM;Johnson RB;Sommergruber W;Shepherd TA View More
9847377 Cleavage of Poly(A)-binding protein by coxsackievirus 2A protease in vitro and in vivo: another mechanism for host protein synthesis shutoff? J Virol 1999 Kerekatte V;Keiper BD;Badorff C;Cai A;Knowlton KU;Rhoads RE View More
9989947 Inhibition of 3C protease from human rhinovirus strain 1B by peptidyl bromomethylketonehydrazides. Arch Biochem Biophys 1999 Kati WM;Sham HL;McCall JO;Montgomery DA;Wang GT;Rosenbrook W;Miesbauer L;Buko A;Norbeck DW View More