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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. |
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Dragovich PS;Prins TJ;Zhou R;Fuhrman SA;Patick AK;Matthews DA;Ford CE;Meador JW 3rd;Ferre RA;Worland ST |
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10197965
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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements. |
J Med Chem |
1999 |
Dragovich PS;Prins TJ;Zhou R;Webber SE;Marakovits JT;Fuhrman SA;Patick AK;Matthews DA;Lee CA;Ford CE;Burke BJ;Rejto PA;Hendrickson TF;Tuntland T;Brown EL;Meador JW 3rd;Ferre RA;Harr JE;Kosa MB;Worland ST |
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Liquid chromatography-mass spectrometry and liquid chromatography-NMR characterization of in vitro metabolites of a potent and irreversible peptidomimetic inhibitor of rhinovirus 3C protease. |
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2001 |
Zhang KE;Hee B;Lee CA;Liang B;Potts BC |
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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. Part 7: structure-activity studies of bicyclic 2-pyridone-containing peptidomimetics. |
Bioorg Med Chem Lett |
2002 |
Dragovich PS;Prins TJ;Zhou R;Johnson TO;Brown EL;Maldonado FC;Fuhrman SA;Zalman LS;Patick AK;Matthews DA;Hou X;Meador JW;Ferre RA;Worland ST |
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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 6. Structure-activity studies of orally bioavailable, 2-pyridone-containing peptidomimetics. |
J Med Chem |
2002 |
Dragovich PS;Prins TJ;Zhou R;Brown EL;Maldonado FC;Fuhrman SA;Zalman LS;Tuntland T;Lee CA;Patick AK;Matthews DA;Hendrickson TF;Kosa MB;Liu B;Batugo MR;Gleeson JP;Sakata SK;Chen L;Guzman MC;Meador JW 3rd;Ferre RA;Worland ST |
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Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP. |
Genes Dev |
1997 |
Freiman RN;Herr W |
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