| Title | Complete genome analysis of a rare human G3P[9] rotavirus posing as an AU-1 like strain. | ||
| Author | Theamboonlers, Apiradee; Maiklang, Ornwalan; Thongmee, Thanunrat; Chieochansin, Thaweesak; Vuthitanachot, Viboonsuk; Poovorawan, Yong | ||
| Journal | Springerplus | Publication Year/Month | 2013 |
| PMID | 24255863 | PMCID | PMC3824699 |
| Affiliation | 1.Center of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University and Hospital, Bangkok, 10330 Thailand. | ||
BACKGROUND: We performed phylogenetic and sequence analysis by Basic Local Alignment Search Tool (BLAST) of a complete Human Rotavirus (HRV) genome isolated from a hospitalized child with acute gastroenteritis in Thailand. FINDINGS: The results indicated an uncommon strain characterized by multiple re-assortments in the VP3, VP4, VP6, NSP1, NSP4 and NSP5 genes. The uncommon strain is genotype G3-P[9]-I3-R3-C3-M3-A3-N3-T3-E3-H6, which displays aspects of the AU-1, FRV-1 and corresponds to the feline/canine prototype G3P[9] strain. CONCLUSIONS: The results suggested that nearly all the eleven gene segments of G3P[9] RVA strain CU365 might have originated from feline/canine RVAs (Rotavirus A).