| Title | Selection of a screening panel of rhinoviral serotypes. | ||
| Author | Tomkinson, Nick; Wenlock, Mark; McCrae, Christopher | ||
| Journal | Bioorg Med Chem Lett | Publication Year/Month | 2012-Dec |
| PMID | 23122823 | PMCID | -N/A- |
| Affiliation | 1.AstraZeneca R&D Alderley Park, Cheshire SK10 4TF, UK. nick.tomkinson@astrazeneca.com. | ||
A novel methodology for the selection of a representative primary and secondary screening panel of rhinoviral serotypes for the purposes of identifying potential antiviral agents is presented. This methodology focuses on the active-sites of the rhinoviral proteins but does not invoke historical SAR data, thereby avoiding compound bias.