In this study, numerical experiments are conducted to examine the robustness of using cascade to describe the multifractal heart rate variability (HRV) by perturbing the hierarchical time scale structure and the multiplicative rule of the cascade. It is shown that a rigid structure of the multiple time scales is not essential for the multifractal scaling in healthy HRV. So long as there exists a tree structure for the multiplication to take place, a multifractal HRV and related properties can be captured by using the cascade. But the perturbation of the multiplicative rule can lead to a qualitative change. In particular, a multifractal to monofractal HRV transition can result after the product law is perturbed to an additive one at the fast time scale. We suggest that this explains the similar HRV scaling transition in the parasympathetic nervous system blockade.