VP4/2-based RV Typing
1. VP4/VP2 sequences are predictive of HRV species and type and can be used for type identification in epidemiological studies.
2. Due to the inherent limitations of the VP4/2 region in RV typing, we recommend using the VP4/2-based RV Typing as a predictive tool or as a supplementary method to VP1-based typing results. When VP1 sequences are available, we strongly advocate for the prioritization of VP1-based RV Typing.
3. Since the RVC58 currently lacks available VP4/2 sequence, we recommend conducting a comprehensive assessment when typing RVC specie, incorporating the results of VP1-based RV typing.
