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Human rhinovirus induces robust IP-10 release by monocytic cells, which is independent of viral replication but linked to type I interferon receptor ligation and STAT1 activation. |
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Attenuated expression of interferon-beta and interferon-lambda1 by human alternatively activated macrophages. |
Hum Immunol |
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Macrophage activation state determines the response to rhinovirus infection in a mouse model of allergic asthma. |
Respir Res |
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Toll-like receptor 2-expressing macrophages are required and sufficient for rhinovirus-induced airway inflammation. |
J Allergy Clin Immunol |
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Han M;Chung Y;Young Hong J;Rajput C;Lei J;Hinde JL;Chen Q;Weng SP;Bentley JK;Hershenson MB |
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Enhanced allergic responsiveness after early childhood infection with respiratory viruses: Are long-lived alternatively activated macrophages the missing link? |
Pathog Dis |
2016 |
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Rhinovirus infection induces distinct transcriptome profiles in polarized human macrophages. |
Physiol Genomics |
2018 |
Rajput C;Walsh MP;Eder BN;Metitiri EE;Popova AP;Hershenson MB |
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Engystol reduces onset of experimental respiratory syncytial virus-induced respiratory inflammation in mice by modulating macrophage phagocytic capacity. |
PLoS One |
2018 |
Wronski S;Dannenmaier J;Schild S;Macke O;Muller L;Burmeister Y;Seilheimer B;Muller M |
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Rhinovirus enters but does not replicate inside monocytes and airway macrophages. |
J Immunol |
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