PMID Title Journal Publication Year Author View in RVdb
10500114 Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes. Proc Natl Acad Sci U S A 1999 Matthews DA;Dragovich PS;Webber SE;Fuhrman SA;Patick AK;Zalman LS;Hendrickson TF;Love RA;Prins TJ;Marakovits JT;Zhou R;Tikhe J;Ford CE;Meador JW;Ferre RA;Brown EL;Binford SL;Brothers MA;DeLisle DM;Worland ST View More
11159387 Molecular dynamics simulations of human rhinovirus and an antiviral compound. Biophys J 2001 Speelman B;Brooks BR;Post CB View More
11302940 Liquid chromatography-mass spectrometry and liquid chromatography-NMR characterization of in vitro metabolites of a potent and irreversible peptidomimetic inhibitor of rhinovirus 3C protease. Drug Metab Dispos 2001 Zhang KE;Hee B;Lee CA;Liang B;Potts BC View More
12515488 Virus-ligand interactions: identification and characterization of ligand binding by NMR spectroscopy. J Am Chem Soc 2003 Benie AJ;Moser R;Bauml E;Blaas D;Peters T View More
12746549 Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. Science 2003 Anand K;Ziebuhr J;Wadhwani P;Mesters JR;Hilgenfeld R View More
21795339 Enterovirus 71 and coxsackievirus A16 3C proteases: binding to rupintrivir and their substrates and anti-hand, foot, and mouth disease virus drug design. J Virol 2011 Lu G;Qi J;Chen Z;Xu X;Gao F;Lin D;Qian W;Liu H;Jiang H;Yan J;Gao GF View More
21835784 Structural basis for antiviral inhibition of the main protease, 3C, from human enterovirus 93. J Virol 2011 Costenaro L;Kaczmarska Z;Arnan C;Janowski R;Coutard B;Sola M;Gorbalenya AE;Norder H;Canard B;Coll M View More
23549610 The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles\' heel": current effective inhibitor targeting a 3C-like protease. Protein Cell 2013 Ren Z;Yan L;Zhang N;Guo Y;Yang C;Lou Z;Rao Z View More
25792507 Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2-P4 study. J Enzyme Inhib Med Chem 2016 Ang MJ;Lau QY;Ng FM;Then SW;Poulsen A;Cheong YK;Ngoh ZX;Tan YW;Peng J;Keller TH;Hill J;Chu JJ;Chia CS View More
34506130 Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode. Biochemistry 2021 Lockbaum GJ;Henes M;Lee JM;Timm J;Nalivaika EA;Thompson PR;Kurt Yilmaz N;Schiffer CA View More
34960671 RIPK1 Is Cleaved by 3C Protease of Rhinovirus A and B Strains and Minor and Major Groups. Viruses 2021 Croft SN;Walker EJ;Ghildyal R View More
7500332 A novel basis of capsid stabilization by antiviral compounds. J Mol Biol 1995 Phelps DK;Post CB View More
7629816 [(Biaryloxy)alkyl]isoxazoles: picornavirus inhibitors. J Med Chem 1995 Guiles JW;Diana GD;Pevear DC View More
7731021 Picornavirus inhibitors: trifluoromethyl substitution provides a global protective effect against hepatic metabolism. J Med Chem 1995 Diana GD;Rudewicz P;Pevear DC;Nitz TJ;Aldous SC;Aldous DJ;Robinson DT;Draper T;Dutko FJ;Aldi C;et al. View More
8057290 Oxadiazoles as ester bioisosteric replacements in compounds related to disoxaril. Antirhinovirus activity. J Med Chem 1994 Diana GD;Volkots DL;Nitz TJ;Bailey TR;Long MA;Vescio N;Aldous S;Pevear DC;Dutko FJ View More
8939746 Human rhinovirus 3 at 3.0 A resolution. Structure 1996 Zhao R;Pevear DC;Kremer MJ;Giranda VL;Kofron JA;Kuhn RJ;Rossmann MG View More
9122218 The pentamer channel stiffening model for drug action on human rhinovirus HRV-1A. Proc Natl Acad Sci U S A 1997 Vaidehi N;Goddard WA 3rd View More
9512706 Influence of an antiviral compound on the temperature dependence of viral protein flexibility and packing: a molecular dynamics study. J Mol Biol 1998 Phelps DK;Rossky PJ;Post CB View More