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Preparing an oncolytic poliovirus recombinant for clinical application against glioblastoma multiforme. |
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Enhanced oncolysis mediated by Coxsackievirus A21 in combination with doxorubicin hydrochloride. |
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Neuroattenuation of vesicular stomatitis virus through picornaviral internal ribosome entry sites. |
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Oncolytic polio virotherapy of cancer. |
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Mitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated translation and viral oncolysis. |
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Brown MC;Dobrikov MI;Gromeier M |
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Cytotoxic and immunogenic mechanisms of recombinant oncolytic poliovirus. |
Curr Opin Virol |
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Brown MC;Gromeier M |
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Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs. |
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2017 |
Brown MC;Holl EK;Boczkowski D;Dobrikova E;Mosaheb M;Chandramohan V;Bigner DD;Gromeier M;Nair SK |
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Engineered Oncolytic Poliovirus PVSRIPO Subverts MDA5-Dependent Innate Immune Responses in Cancer Cells. |
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Walton RW;Brown MC;Sacco MT;Gromeier M |
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Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma. |
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2021 |
Beasley GM;Nair SK;Farrow NE;Landa K;Selim MA;Wiggs CA;Jung SH;Bigner DD;True Kelly A;Gromeier M;Salama AK |
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Oncolytic Virotherapy Treatment of Breast Cancer: Barriers and Recent Advances. |
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Kwan A;Winder N;Muthana M |
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Oncolytic Viral Therapy for Malignant Glioma and Their Application in Clinical Practice. |
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Shoaf ML;Desjardins A |
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