| Title | Recent structural solutions for antibody neutralization of viruses. | ||
| Author | Stewart, P L; Nemerow, G R | ||
| Journal | Trends Microbiol | Publication Year/Month | 1997-Jun |
| PMID | 9211643 | PMCID | -N/A- |
| Affiliation | 1.Dept of Molecular and Medical Pharmacology, UCLA School of Medicine 90095-1770, USA. pstewart@mail.nuc.ucla.edu. | ||
Structural studies of virus-antibody interactions can offer insights into mechanisms of virus neutralization and immune escape. Crystallography and cryoelectron microscopy can reveal the structural relationship between receptor-binding sites and neutralization epitopes, as well as whether molecular rearrangements occur upon antibody binding.