| Title | Detection of rhinovirus in sinus brushings of patients with acute community-acquired sinusitis by reverse transcription-PCR. | ||
| Author | Pitkaranta, A; Arruda, E; Malmberg, H; Hayden, F G | ||
| Journal | J Clin Microbiol | Publication Year/Month | 1997-Jul |
| PMID | 9196195 | PMCID | PMC229843 |
| Affiliation | 1.Department of Internal Medicine, University of Virginia, Charlottesville 22908, USA. | ||
Of 20 adults with acute community-acquired sinusitis (ACAS), rhinovirus was detected in specimens from 10 (50%) patients, including maxillary aspirates from 8 (40%) patients and nasal swabs from 9 (45%) patients, by reverse transcription-PCR (RT-PCR). Human coronavirus was detected by RT-PCR in nasal swabs from 3 of 20 patients but in no sinus secretions. These findings suggest that rhinovirus is an important cause of ACAS and that viral invasion of the sinus cavity itself may be a common event during the disease.