| Title | Method for detection of picornavirus capsid binders with soluble intercellular adhesion molecule 1. | ||
| Author | Last-Barney, K; Marlin, S D; Pal, K; Cahill-Feehan, C; McNally, E J; Jeanfavre, D D; Merluzzi, V J | ||
| Journal | Antimicrob Agents Chemother | Publication Year/Month | 1993-Aug |
| PMID | 8105750 | PMCID | PMC188044 |
| Affiliation | 1.Department of Immunology, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut 06877. | ||
A method utilizing immobilized major group rhinoviruses and biotinylated soluble intercellular adhesion molecule 1 has been developed for the detection of capsid binders. Binding measurements indicate a loss in relative affinity of biotinylated soluble intercellular adhesion molecule 1 for rhinoviruses by capsid binders. This method and a new class of capsid binders are discussed.