| Title | Enhancement of human rotavirus infectivity in a monkey kidney cell line by human expressed breast milk. | ||
| Author | Totterdell, B M; MacLeod, J; Chrystie, I L; Banatvala, J E | ||
| Journal | J Med Virol | Publication Year/Month | 1982 |
| PMID | 6286865 | PMCID | -N/A- |
Eight of forty (20%) human expressed breast milks enhanced the infectivity of human rotavirus (HRV) when assayed by immunofluorescence in a monkey kidney cell line (LLC-MK2). This enhancement was demonstrated with two HRV strains, one derived from a fecal specimen of a child with acute gastroenteritis, the other a tissue culture adapted strain. The phenomenon could have important implications in the pathogenesis of HRV infections and in future vaccine programs.