Title Effects of Preoperative Sarcopenia-Related Parameters on Cardiac Autonomic Function in Women with Obesity Following Bariatric Surgery: A One-Year Prospective Study.
Author Crispim Carvalho, Nara Nobrega; Baccin Martins, Vinicius Jose; da Nobrega, Vinicius Almeida; de Arruda Neta, Adelia da Costa Pereira; Cavalcante da Fonseca, Luis Antonio; Bandeira, Francisco; de Brito Alves, Jose Luiz
Journal Nutrients Publication Year/Month 2023-Jun
PMID 37375560 PMCID PMC10301886
Affiliation + expend 1.Department of Nutrition, Health Sciences Center, Federal University of Paraiba, Joao Pessoa 58010-780, Brazil.

OBJECTIVES: Investigate changes in blood pressure (BP) and heart rate variability (HRV) in women with and without sarcopenia-related parameters who underwent bariatric surgery (BS) during a one-year follow-up. SUBJECTS AND METHODS: Women were separated into obesity (OB, n = 20) and women with obesity displaying sarcopenia-related parameters (SOP, n = 14) and evaluated before BS and 3, 6, and 12 months after BS. SOP was defined as low handgrip strength (HS) and/or low appendicular skeletal mass adjusted for weight (ASM/wt x 100, %) in the lowest quartile of the sample. ASM/wt x 100, % and HS were significantly lower in SOP than OB over a one-year follow-up of BS (p < 0.05). RESULTS: There was a reduction in diastolic BP, heart rate (HR), SDHR, LF, and the LF/HF ratio (p < 0.05) and an increase in the HF band in both groups during the follow-up period (p < 0.05). SOP women had reduced root mean square differences of successive RR intervals (RMSSD) and HF band and an increased LF band and SD2/SD1 ratio compared to the OB group during the one-year follow-up (p < 0.05). ASM/wt x 100, % was negatively associated with the LF band (r = -0.24, p = 0.00) and positively associated with the HF band (r = 0.22, p = 0.01). Conversely, HS had no association with LF (r = -0.14, p = 0.09) and HF (r = 0.11, p = 0.19). ASM/wt x 100, % and HS were negatively associated with the LF/HF ratio (p < 0.05). CONCLUSIONS: Women who underwent BS had an improved HRV over a one-year follow-up. However, the improvement in HRV variables was less pronounced in women with low muscle mass and/or HS during the follow-up period.

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