Title COVID-19, Influenza, and Other Acute Respiratory Viral Infections: Etiology, Immunopathogenesis, Diagnosis, and Treatment. Part I. COVID-19 and Influenza.
Author Ilyicheva, T N; Netesov, S V; Gureyev, V N
Journal Mol Gen Microbiol Virol Publication Year/Month 2022
PMID 35936505 PMCID PMC9342941
Affiliation 1.Novosibirsk State University, 630090 Novosibirsk, Russia. GRID: grid.4605.7. ISNI: 0000000121896553;Vector State Research Center of Virology and Biotechnology, 630559 Koltsovo, Russia.

The paper briefly reviews pathogens causing acute respiratory viral infections (ARVIs), including influenza viruses; coronaviruses, including SARS-CoV-2; parainfluenza viruses, adenoviruses, pneumoviruses, and specifically respiratory syncytial virus and metapneumoviruses, enteroviruses, rhinoviruses, and bocaviruses. This review presents modern data on the structure and replication of viruses, epidemiology, and immunopathogenesis of diseases and on diagnostics, preventive vaccination, and antiviral drugs for the treatment of ARVIs. Special attention is paid to the SARS-CoV-2 virus caused COVID-19 pandemic with analyses of similarities and differences between COVID-19 and other ARVIs, first of all, influenza virus. Topical issues regarding ARVI vaccination and the search for new broad-spectrum antiviral drugs are discussed.

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