| Title | SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population? | ||
| Author | Pereira, Maria Fernanda Badue; Suguita, Priscila; Litvinov, Nadia; Farhat, Sylvia Costa Lima; Paula, Camila Sanson Yoshino de; Lazari, Carolina Dos Santos; Bede, Pedro Vale; Framil, Juliana Valeria de Souza; Bueno, Catarina; Branas, Priscila Cristina Abduch Adas; Guimaraes, Irina Monteiro da Costa; Leite, Marcia Marques; Navega, Ana Carolina Barsaglini; Nanbu, Danilo Yamamoto; Schvartsman, Claudio; Pinho, Joao Renato Rebello; Silva, Clovis Artur Almeida; Marques, Heloisa Helena de Sousa; Eisencraft, Adriana Pasmanik; Rossi, Alfio Jr; Delgado, Artur Figueiredo; Leal, Gabriela Nunes; Gibelli, Maria Augusta Cicaroni; Palmeira, Patricia; Sakita, Neusa Keico; Santos, Emilly Henrique Dos; Rocha, Mussya Cisotto; Kanunfre, Kelly Aparecida; Okay, Thelma Suely; Carneiro-Sampaio, Magda; Carvalho, Werther Brunow de | ||
| Journal | Rev Inst Med Trop Sao Paulo | Publication Year/Month | 2022 |
| PMID | 35648987 | PMCID | PMC9134860 |
| Affiliation + expend | 1.Universidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas, Instituto da Crianca e do Adolescente, Departamento de Pediatria, Unidade de Infectologia Pediatrica, Sao Paulo, Sao Paulo, Brazil. | ||
This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for other respiratory pathogens (ORP). Patients with laboratory-confirmed COVID-19 or ORP were included. We evaluated 76 pediatric COVID-19 infections and 157 other respiratory virus infections. Rhinovirus occurred in 132/157 (84%). COVID-19 patients who were significantly older, had more fevers, headaches and pneumonia than those with ORP. The median white blood cell count was lower in patients with SARS-CoV-2 than in those with ORP (6,470 versus 8,170; p=0.02). COVID-19 patients had significantly worse symptoms than those with ORP.