Title Disruption of the Cortical-Vagal Communication Network in Parkinson\'s Disease.
Author Pardo-Rodriguez, MariNieves; Bojorges-Valdez, Erik; Yanez-Suarez, Oscar
Journal Annu Int Conf IEEE Eng Med Biol Soc Publication Year/Month 2021-Nov
PMID 34892448 PMCID -N/A-

Parkinson\'s disease (PD) is a neuropathy characterized by motor disorders, but it has also been associated with the presence of autonomic alterations as a result of degradation of the dopaminergic system. Studying the relation between Band Power time series (BPts) and Heart Rate Variability (HRV), has been proposed as a tool to explore the bidirectional communication pathways between cortex and autonomic control. This work presents a primer analysis on study brain <--> heart interaction on a databse of PD patients under two conditions: without and after levadopa (L-dopa) intake. Additionally a healthy control population was also analyzed, and used as comparison level between both conditions. Results show PD affects pathways by reducing the number of connections, specially association of beta and power and the second faster component of HRV seems to be more sensitive to L-dopa administration.

  • Copyright © 2023
    National Institute of Pathogen Biology, CAMS & PUMC, Bejing, China
    All rights reserved.