| Title | Binding and entering: COVID finds a new home. | ||
| Author | Vu, Michelle N; Menachery, Vineet D | ||
| Journal | PLoS Pathog | Publication Year/Month | 2021-Aug |
| PMID | 34460863 | PMCID | PMC8404997 |
| Affiliation + expend | 1.Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America. | ||
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged as a virus with a pathogenicity closer to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and a transmissibility similar to common cold coronaviruses (CoVs). In this review, we briefly discuss the features of the receptor-binding domain (RBD) and protease cleavage of the SARS-CoV-2 spike protein that enable SARS-CoV-2 to be a pandemic virus.