| Title | Heart rate characteristics monitoring and reduction in mortality or neurodevelopmental impairment in extremely low birthweight infants with sepsis. | ||
| Author | King, William E; Carlo, Waldemar A; O'Shea, T Michael; Schelonka, Robert L | ||
| Journal | Early Hum Dev | Publication Year/Month | 2021-Aug |
| PMID | 34247026 | PMCID | -N/A- |
| Affiliation + expend | 1.Medical Predictive Science Corporation, 1233 Cedars Court Suite 201, Charlottesville, VA 22903, United States of America. Electronic address: wking@heroscore.com. | ||
We questioned whether a heart rate characteristics (HRC) sepsis risk score displayed to clinicians would modify 18-22 month neurodevelopmental outcomes for extremely low birthweight infants who develop sepsis. Infants allocated to HRC display with sepsis had a 12% absolute reduction in the composite outcome of death or neurodevelopmental impairment. TRIAL REGISTRATION: NCT00307333.