Title Identification of SARS-CoV-2 and additional respiratory pathogens cases under the investigation of COVID-19 initial phase in a Brazilian reference laboratory.
Author Matos, Aline da Rocha; Motta, Fernando Couto; Caetano, Braulia Costa; Ogrzewalska, Maria; Garcia, Cristiana Couto; Lopes, Jonathan Christian Oliveira; Miranda, Milene; Livorati, Miriam Teresinha Furlam Prando; Abreu, Andre; Brown, David; Siqueira, Marilda Mendonca
Journal Mem Inst Oswaldo Cruz Publication Year/Month 2020
PMID 32965332 PMCID PMC7508282
Affiliation + expend 1.Fundacao Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratorio de Virus Respiratorios e do Sarampo, Rio de Janeiro, RJ, Brasil.

Coronavirus disease 2019 (COVID-19) surveillance, in Brazil, initiated shortly after its description, in China. Our aim was to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and additional pathogens in samples from the initial phase of the outbreak in Brazil, from late February to late March. From 707 samples analysed, 29 (4.1%) were SARS-CoV-2 positive. Fever and cough were their most prevalent symptoms. Co-detection of rhinovirus was observed in 2 (6.9%) cases. Additional pathogens were identified in 66.1% of the SARS-CoV-2 negative cases, mainly rhinovirus and influenza A(H1N1)pdm09. Thus, we emphasise the importance of differential diagnosis in COVID-19 suspected cases.

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