AIM: The purpose of the study is to assess the characteristics of heart risk variability in patients with non - alcoholic fatty liver disease (NAFLD). MATERIALS AND METHODS: The study included 103 patients. All patients were divided into three groups. The first group is 34 healthy patients. The second group - 34 patients with a diagnosis of coronary artery disease; exertional angina II-III FC. The third group - 35 patients diagnosed with NAFLD and type 2 diabetes. An assessment of abdominal circumference, body mass index, ALT, AST, XC, HDL, LDL, TG, glucose and the level of glycated hemoglobin (HbA1c), liver ultrasound and daily ECG monitoring with the determination of HRV were evaluated. Evaluated HRV using statistical analysis: avNN, ms; pNN 50%; SDNNidx, ms; SDNN, ms; SDNNidx, ms; RMSSD, ms. HRV characteristics were evaluated: VLF, LF, HF, LF/HF. RESULTS: Compared with the first group, the increase in cholesterol in patients in the second group was noted by 38.8%, in the third group - by 43.7%, TG - by 34.6 and 41.95%. In patients with NAFLD + DM of the second type, SDNN and SDNNidx decreased in comparison with the healthy patients by 15% (p.