AIM: To develop the algorithm of prognosis and prevention of climatic maladaptation in healthy young people with peculiarities of the autonomic nervous system (VNS) during off-season and treatment the identified disturbances with reflexotherapy. MATERIAL AND METHODS: VNS functions were assessed in load conditions in 145 people in the beginning and in the end of a rest at the Black Sea coast. The Vein\'s questionnaire, active orthoclinostatic test (AOT), and heart rate variability (HRV) analysis and ECG recording were used. Spielberger-Khanin test was administered to assess anxiety. Autonomic disorders caused by climatic maladaptation were treated with reflexotherapy. RESULTS: AOT has shown VNS dysfunctions in 67.7% of subjects, HRV analysis in 54.3%, and the Vein questionnaire in 96.55%. There was no significant difference between the results of AOT and HRV analysis, while the Vein questionnaire results exceeded them both (Pearson chi(2), p<0.05), being 1,4 times greater than the HRV analysis result. This higher percentage is explained by the high level of subjects\' trait anxiety. CONCLUSION: The practical value of the Vein questionnaire for the diagnosis, choice and assessment of treatment is confirmed.