| Title | Real-time heart rate variability analysis as a means of hypercapnia detection. | ||
| Author | Dituri, Joseph; Siddiqi, Farhan; Frisina, Robert | ||
| Journal | Undersea Hyperb Med | Publication Year/Month | 2019-Jun-Jul-Aug - Third |
| PMID | 31509906 | PMCID | -N/A- |
| Affiliation + expend | 1.International Board of Undersea Medicine, Medical Engineering, University of South Florida, Tampa, Florida U.S. | ||
We hypothesized that heart rate variability (HRV) can be used as a physiological monitor of exposures to hypercapnia. HRV was analyzed in 15 male subjects breathing air and then air plus 4%, 5% or 6% carbon dioxide (CO2). A progressive elevation in randomness of HRV best depicted as a divergence of data on Poincar e plots of self-similarity occurred as CO2 increased, and resolved when returning sd to ambient conditions. Results indicate that HRV may be useful as a prompt (???2 minute) early warning of hypercapnia that occurs prior to overt symptomatology.