| Title | Respiratory Virus Epidemiology Among US Infants With Severe Bronchiolitis: Analysis of 2 Multicenter, Multiyear Cohort Studies. | ||
| Author | Hasegawa, Kohei; Goto, Tadahiro; Hirayama, Atsushi; Laham, Federico R; Mansbach, Jonathan M; Piedra, Pedro A; Camargo, Carlos A Jr | ||
| Journal | Pediatr Infect Dis J | Publication Year/Month | 2019-Aug |
| PMID | 31306402 | PMCID | PMC6636850 |
| Affiliation + expend | 1.From the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. | ||
In 2 multicenter cohort studies of 2912 infants hospitalized for bronchiolitis during 2007-2014, the 5 most common pathogens were RSV (76.5%), rhinovirus (23.8%), coronavirus (6.9%), adenovirus (6.4%) and human metapneumovirus (6.0%). Hospitalization months significantly differed for these common pathogens (P </= 0.01), except for coronavirus (P = 0.30). There was a significant heterogeneity in temporal patterns by region in RSV-A and -B (both P < 0.001).