OBJECTIVE: The aim of the study was to investigate the effect of physicians\' supportive communication on analogue patients\' (APs) heart rate variability (HRV) and recall, while watching a video of palliative treatment being explained to a female patient. METHODS: Sixty healthy women, acting as APs, were randomly assigned to watch one of two versions (standard vs. affective) of a scripted video-vignette of a bad news consultation to a female patient. The physician\'s communication differed only in the delivery of four supportive comments. Empathy, support and engagement perception were assessed by three questions. APs\' HR was recorded during video-observation and recall was assessed immediately after. HRV was determined through measures defined in time and frequency domains. RESULTS: Data of 54 APs (27鈥?鈥?7) were included. The group with supportive communication perceived the physician as more empathic and supportive. Intra- and Inter-group comparisons suggested a greater sense of stress in the standard communication group. Recall did not differ in the two groups. CONCLUSION AND PRACTICE IMPLICATIONS: Findings show that the use of supportive expressions contribute to the perception of the physician as more empathic, potentially buffer patients\' arousal after a bad news announcement, but does not confirm a positive impact on general recall.