OBJECTIVE: Introduction: Today there is no data on the relationship between body mass index (BMI), total body fat (TBF), visceral fat content (VFC), and the nonfat mass (NFM) content with ANS indices. The aim:To reveal the relationship between the indicators of the functional state of the ANS and body composition. PATIENTS AND METHODS: Materials and methods: The subject of this study were 34 young women with age from 18 to 25. The weight and the indices of body composition were measured by bodyanalizator Tanita BC-601. The functional state of the ANS was measured by "CARDIOLAB". RESULTS: Results: The results show the dependence of the components of the body mass on the activity of the ANS. It has been established that girls with an anxiety disorder, which manifests themselves in the form of lowering the cardiac rhythm variability (HRV) and parasympathetic activity, as well as the simultaneous growth of activity of sympathetic nervous regulation and central neurohumoral influences, is characterized by an increase in BMI, TBF and VFC, and a decrease in NFM. CONCLUSION: Conclusions:Changes in HRV should be considered as potential markers of metabolic disturbances, with the subsequent occurrence of obesity. The estimation of the functional state of the ANS according to the data of the HRV in case of disturbance of the ratio of the constituents of the body mass components will allow to optimize medical approaches for normalization of the vegetative tone and body weight with its composition parameters.