Title Heart Rate Variability Markers as Correlates of Survival in Recipients of Hematopoietic Cell Transplantation.
Author Scheiber, Caroline; Johnston, Laura; Packer, Mary; Gevirtz, Richard; Edwards, Katharine S; Palesh, Oxana
Journal Oncol Nurs Forum Publication Year/Month 2018-Mar
PMID 29466350 PMCID -N/A-
Affiliation + expend 1.Stanford University.

OBJECTIVES: To assess pre-/post-transplantation changes in autonomic tone, as measured by heart rate variability (HRV), among patients undergoing hematopoietic cell transplantation (HCT) and to look at those changes as they relate to post-transplantation survival rates. 鈥? SAMPLE & SETTING: Data were derived from a sample of 27 English-speaking patients undergoing allogeneic or autologous HCT at Stanford University. 鈥? METHODS & VARIABLES: A survival analysis using the Kaplan-Meier estimator was employed to explore whether increased HRV would enhance survival probabilities over time among patients undergoing HCT.鈥? RESULTS: An increased probability of survival was significantly related to increases in two HRV indexes. IMPLICATIONS FOR NURSING: HRV may be a useful predictor of mortality among patients undergoing HCT. Interventions deliverable by nurses could be used to enhance HRV for patients identified as being at risk for early mortality.

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