| Title | A case series on the potential effect of omega-3-fatty acid supplementation on 24-h heart rate variability and its circadian variation in children with attention deficit (hyperactivity) disorder. | ||
| Author | Buchhorn, Reiner; Koenig, Julian; Jarczok, Marc N; Eichholz, Hanna; Willaschek, Christian; Thayer, Julian F; Kaess, Michael | ||
| Journal | Atten Defic Hyperact Disord | Publication Year/Month | 2018-Jun |
| PMID | 28975530 | PMCID | -N/A- |
| Affiliation + expend | 1.Department of Paediatrics, Klinik fur Kinder- und Jugendmedizin, Caritas Krankenhaus, Uhlandstr. 7, 97980, Bad Mergentheim, Germany. reiner.buchhorn@ckbm.de. | ||
Attention deficit disorder with and without hyperactivity (ADHD) in children is associated with decreased 24-h heart rate variability (HRV). Previous research has shown that supplementation of omega-3-fatty acid increases HRV. Here, we aimed to investigate whether the supplementation of omega-3-fatty acids would increase 24-h HRV in an uncontrolled case series of children with ADHD. HRV was recorded in 18 children and adolescents (age 13.35 +/- 2.8 years) before and after omega-3 supplementation. Preliminary results indicate that omega-3 supplementation in children with AD(H)D may reduce mean heart rate and increase its variability. Future studies would do well to implement randomized, placebo-controlled designs with greater methodological rigor.