| Title | The nucleotide sequence of human rhinovirus 1B: molecular relationships within the rhinovirus genus. | ||
| Author | Hughes, P J; North, C; Jellis, C H; Minor, P D; Stanway, G | ||
| Journal | J Gen Virol | Publication Year/Month | 1988-Jan |
| PMID | 2826669 | PMCID | -N/A- |
| Affiliation | 1.Department of Biology, University of Essex, Colchester, U.K. | ||
We have determined the complete nucleotide sequence of human rhinovirus 1B and made comparisons with other rhinoviruses. Extensive homology was found with serotypes 2 and 89 but the similarity to serotype 14 was considerably less. Rhinovirus-specific characteristics have been noted, in particular the length of the 5\' non-coding region and the pattern of codon usage, and these may be sufficient to define the rhinoviruses as a distinct genus rather than being considered as members of the enteroviruses as has been suggested previously.