| Title | Disseminated rhinovirus C8 infection with infectious virus in blood and fatal outcome in a child with repeated episodes of bronchiolitis. | ||
| Author | Lupo, Julien; Schuffenecker, Isabelle; Morel-Baccard, Christine; Bardet, Julie; Payen, Valerie; Kaiser, Laurent; Constant, Samuel; Lobrinus, Johannes Alexander; Lin-Marq, Nathalie; Lina, Bruno; Morand, Patrice; Tapparel, Caroline | ||
| Journal | J Clin Microbiol | Publication Year/Month | 2015-May |
| PMID | 25694520 | PMCID | PMC4400751 |
| Affiliation + expend | 1.Laboratory of Virology, University Hospital of Grenoble, Grenoble, France Unit of Virus Host Cell Interactions UMI 3265 UJF-EMBL-CNRS, Grenoble, France jlupo@chu-grenoble.fr. | ||
We report a fatal case of acute lower respiratory tract disease with human rhinovirus C (HRV-C) as the unique cause in a 19-month-old girl with a history of repeated episodes of bronchiolitis. HRV-C type 8 nucleic acids were observed in respiratory, stool, and cerebrospinal fluid samples, and infectious virions were isolated from patient serum after inoculation onto reconstituted airway epithelia.