| Title | High respiratory virus oropharyngeal carriage rate during Kingella kingae osteoarticular infections in children. | ||
| Author | Basmaci, Romain; Bonacorsi, Stephane; Ilharreborde, Brice; Doit, Catherine; Lorrot, Mathie; Kahil, Mahmoud; Visseaux, Benoit; Houhou, Nadhira; Bidet, Philippe | ||
| Journal | Future Microbiol | Publication Year/Month | 2015 |
| PMID | 25598333 | PMCID | -N/A- |
| Affiliation | 1.INSERM, IAME, UMR 1137, F-75018 Paris, France. | ||
AIM: Kingella kingae osteoarticular (KKO) infections are frequently associated with upper respiratory tract infections. However, no comparative studies detecting respiratory viruses had ever been performed between KKO and non-KKO (NKO). PATIENTS & METHODS: Eighteen viruses were searched by FilmArray((R)) Respiratory Panel (BioFire Diagnostics, UT, USA) in the oropharynx of 6-to-48-month-children admitted for KKO and NKO in 2013. RESULTS: At least one virus was detected in the oropharynx of 19/21 (90.5%) KKO and 3/8 (37.5%) NKO cases (p = 0.008). In KKO group, human rhinovirus was predominant (12/21; 57.1%), especially during winter (7/11; 63.6%) despite its low concomitant circulation (<10%). Human rhinovirus was found in 2/8 (25%) in NKO group. CONCLUSION: Higher prevalence of respiratory virus in oropharynx was observed in KKO than NKO, strengthening their putative role in KKO pathophysiology.