Title Assessing complexity of heart rate variability in people with spinal cord injury using local scale exponents.
Author Liao, Fuyuan; Brooks, Ian; Hsieh, Chang-Wei; Rice, Ian M; Jankowska, Maria M; Jan, Yih-Kuen
Journal Annu Int Conf IEEE Eng Med Biol Soc Publication Year/Month 2014
PMID 25571456 PMCID PMC4302051

Detrended fluctuation analysis (DFA) has been widely used to study dynamics of heart rate variability (HRV), which provides a quantitative parameter, the scaling exponent a, to represent the correlation properties of RR interval series. However, it has been demonstrated that HRV exhibits complex behavior that cannot be fully described by a single exponent. This study aimed to investigate whether local scale exponent alpha(t) with t being the time scale can reveal new features of HRV that cannot be reflected by DFA coefficients. To accurately estimate alpha(t), we developed an approach for correcting a(t) at small scales and verified the approach using simulated signals. We studied HRV in 12 subjects with spinal cord injury and 14 able-bodied controls during sitting and prone postures. The results showed that alpha(t) provides complementary views of HRV, suggesting that it may be used to evaluate the effects of SCI-induced autonomic damage on HRV.

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