| Title | Typing of human rhinoviruses based on sequence variations in the 5\' non-coding region. | ||
| Author | Torgersen, H; Skern, T; Blaas, D | ||
| Journal | J Gen Virol | Publication Year/Month | 1989-Nov |
| PMID | 2555441 | PMCID | -N/A- |
| Affiliation | 1.Institut fur Biochemie, Universitat Wien, Vienna, Austria. | ||
Unambiguous assignment of restriction enzyme patterns to six individual serotypes of human rhinovirus was accomplished after amplification of a 380 bp DNA fragment derived from the 5\' non-coding region. This was possible even though serotypes 1A and 1B and serotypes 2 and 49 differed only at 10 and 15 positions respectively. The method utilizes the conserved and variable components of this part of the genome and provides the basis for a simple and rapid method for typing of human rhinoviruses.