Title A novel method to estimate changes in stress-induced salivary alpha-amylase using heart rate variability and respiratory rate, as measured in a non-contact manner using a single radar attached to the back of a chair.
Author Matsui, Takemi; Katayose, Satoshi
Journal J Med Eng Technol Publication Year/Month 2014-Aug
PMID 24936962 PMCID -N/A-
Affiliation 1.Department of Management Systems Engineering, Tokyo Metropolitan University , 6-6 Asahigaoka, Hino, Tokyo , Japan.

The authors have developed a non-contact system which estimates changes in salivary alpha-amylase (sAA ratio) induced by stress. Before and after stressful sound exposure, a single 24 GHz compact radar which is attached to the back of a chair measures the low frequency (LF) component of heart rate variability and respiratory rate, alpha-amylase in the subjects\' buccal secretions was measured by using an alpha-amylase assay kit. Using multiple regression analysis, sAA ratio was estimated using stress-induced LF change (LF ratio) and stress-induced respiratory rate change (respiratory rate ratio). Twelve healthy subjects were tested (12 males, 22 +/- 2 years), who were exposed to audio stimuli with a composite tone of 2120 Hz and 2130 Hz sine waves at a sound pressure level of 95 dB after a silent period through a headphone. The result showed that sAA ratio estimated using multiple regression analysis significantly correlated with measured sAA ratio (R = 0.76, p < 0.01). This indicates that the system may serve for a stress management in the future.

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