Title | [Early steps of picornavirus infection]. | ||
Author | Koike, Satoshi | ||
Journal | Uirusu | Publication Year/Month | 2011-Dec |
PMID | 22916565 | PMCID | -N/A- |
Affiliation | 1.Neurovirology Project, Tokyo Metropolitan Institute of Medical Science. koike-st@igakuken.or.jp. |
Picornaviridae is a large family of viruses that cause a variety of infectious diseases in humans and animals. It includes important viruses such as poliovirus, hepatisis A virus and foot and mouth disease virus. Early steps of infection play important roles in determining the host range and the target organs for each virus. Here, I review the recent advances in the studies of cellular receptors for picornaviruses, mechanisms of cell entry and viral uncoating.