Title [Early steps of picornavirus infection].
Author Koike, Satoshi
Journal Uirusu Publication Year/Month 2011-Dec
PMID 22916565 PMCID -N/A-
Affiliation 1.Neurovirology Project, Tokyo Metropolitan Institute of Medical Science. koike-st@igakuken.or.jp.

Picornaviridae is a large family of viruses that cause a variety of infectious diseases in humans and animals. It includes important viruses such as poliovirus, hepatisis A virus and foot and mouth disease virus. Early steps of infection play important roles in determining the host range and the target organs for each virus. Here, I review the recent advances in the studies of cellular receptors for picornaviruses, mechanisms of cell entry and viral uncoating.

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